Results 1 to 10 of about 492,856 (153)

Ultrafast synthesis of α-aminophosphonates using ternary deep eutectic solvent in water [PDF]

open access: yesScientific Reports
A remarkably rapid synthesis of α-aminophosphonate medicinally privileged scaffold is developed using a ternary deep eutectic solvent (TDES) of urea/SnCl2/HCl catalyst.
Najmedin Azizi   +3 more
doaj   +2 more sources

Old and Modern Antibiotic Structures with Potential for Today’s Infections

open access: yesADMET and DMPK, 2022
Due to the lack of new antibiotics with efficacy against the ESKAPE and other resistant microbes, coupled to the demise of major pharmaceutical company antibiotic discovery programs, due to a number of factors but mainly ROI calculations and the lack of ...
David Newman
doaj   +1 more source

Comparison of the Conventional and Mechanochemical Syntheses of Cyclodextrin Derivatives

open access: yesMolecules, 2023
Many scientists are working hard to find green alternatives to classical synthetic methods. Today, state-of-the-art ultrasonic and grinding techniques already drive the production of organic compounds on an industrial scale.
László Jicsinszky   +3 more
doaj   +1 more source

Early synthetic textile dyes of the late 19th century from the “Primo Levi” Chemistry Museum (Rome): A multi-technique analytical investigation

open access: yesJournal of Cultural Heritage, 2023
In the present work a historical collection of early synthetic dyes belonging to an Italian museum was investigated through different analytical techniques: Fourier-transform Infrared (FTIR), UV-visible, Raman and surface-enhanced Raman (SERS) spectroscopies, CHN elemental analysis, electron-spray ionization mass spectrometry (ESI-MS) and X-ray ...
Margherita Longoni   +3 more
openaire   +3 more sources

Benzo[1,2,3]dithiazole Compounds: A History of Synthesis and Their Renewed Applicability in Materials and Synthetic Chemistry, Originating from the Herz Reaction

open access: yesReactions, 2021
The benzo[1,2,3]dithiazole is a unique heteroaromatic functionality whose conjugated profile instils some fascinating electronic properties. This has been historically recognized in the design and manufacture of organic dyes early last century. Although,
Alexander J. Nicholls, Ian R. Baxendale
doaj   +1 more source

Fuelling the Digital Chemistry Revolution with Language Models

open access: yesCHIMIA, 2023
The RXN for Chemistry project, initiated by IBM Research Europe – Zurich in 2017, aimed to develop a series of digital assets using machine learning techniques to promote the use of data-driven methodologies in synthetic organic chemistry.
Antonio Cardinale   +12 more
doaj   +1 more source

Development of Advanced Macrosphelides: Potent Anticancer Agents

open access: yesMolecules, 2015
Synthetic approaches to macrosphelide derivatives, based on medicinal chemistry, are summarized. This review contains conventional medicinal chemistry approaches, combinatorial chemistry, fluorous tagging techniques and affinity chromatography ...
Seung-Mann Paek
doaj   +1 more source

Time-resolved fluorescence observation of di-tyrosine formation in horseradish peroxidase upon ultrasound treatment leading to enzyme inactivation [PDF]

open access: yes, 2016
The application of ultrasound to a solution can induce cavitional phenomena and generate high localised temperatures and pressures. These are dependent of the frequency used and have enabled ultrasound application in areas such as synthetic, green and ...
Bremner, David H.   +4 more
core   +2 more sources

Poly(triazolyl methacrylate) glycopolymers as potential targeted unimolecular nanocarriers [PDF]

open access: yes, 2019
© The Royal Society of Chemistry 2019.Synthetic glycopolymers are increasingly investigated as multivalent ligands for a range of biological and biomedical applications.
Fernandez-Trillo, F.   +12 more
core   +4 more sources

Síntese de cristais líquidos derivados do nitroazobenzeno: uma proposta de síntese multi-etapas aplicada às aulas de química orgânica experimental

open access: yesQuímica Nova, 2014
We describe a synthetic route consisting of five steps from aniline to obtain liquid crystal compounds derived from nitroazobenzene. Syntheses were performed during the second half of the semester in organic chemistry laboratory classes.
Rodrigo Cristiano   +3 more
doaj   +1 more source

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