Results 71 to 80 of about 16,602 (194)

Incidence of Hepatitis B Virus Reactivation in Patients Treated With Immunosuppressive and Chemotherapeutic Agents

Alimentary Pharmacology &Therapeutics, EarlyView.
HBV reactivation incidence varied across immunosuppressive and chemotherapeutic agents. Clinically meaningful HBV reactivation was also observed in patients receiving corticosteroids and conventional immunosuppressive therapies. ABSTRACT Background Data on the incidence of hepatitis B virus reactivation (HBVr) remain limited. In Japan, patients who are
Kazuhiko Ikeuchi, Makoto Saito, Kazuya Okushin, Toshiyuki Kishida, Akira Kado, Kyoji Moriya, Kazuhiko Koike, Takeya Tsutsumi, Hiroshi Yotsuyanagi   +8 more
wiley   +1 more source

Hypericin Suppresses Liver Cancer Through Autophagic Degradation of AKT and Eliciting Antitumor Immune Response

Cancer Science, EarlyView.
Hypericin induces autophagic AKT degradation by promoting AKT‐HSPA5 interaction in an S473 phosphorylation‐dependent manner, suppressing HCC growth. It enhances CD8+ T cell‐mediated antitumor immunity and synergizes with anti‐PD‐L1 therapy, showing favorable safety for HCC treatment. ABSTRACT Hepatocellular carcinoma (HCC) is the most prevalent primary
Sien Ma, Qianqian Xu, Mengjuan Zhu, Xianming Ge, Jian Xu, Yan Pan, Mengli Wang, Yuting Zhu, Aoxuan Xu, Hanmeng Liu, GuangHai Xiang, Weipeng Gong, Bao Zhao   +12 more
wiley   +1 more source

A concise review of updated global guidelines for the management of hepatocellular carcinoma: 2017-2024 [PDF]

Journal of Liver Cancer
Many guidelines for hepatocellular carcinoma (HCC) have been published and are regularly updated worldwide. HCC management involves a broad range of treatment options and requires multidisciplinary care, resulting in significant heterogeneity in ...
Hyunjae Shin, Su Jong Yu
doaj   +1 more source

Biliary Abnormality on Imaging During Lenvatinib Plus Hepatic Arterial Infusion Chemotherapy With Cisplatin for Hepatocellular Carcinoma: A Pilot Descriptive Study

Hepatology Research, EarlyView.
ABSTRACT Aim To evaluate the frequency, imaging characteristics, associated factors, and clinical significance of biliary abnormalities on imaging in patients receiving lenvatinib (LEN) plus cisplatin hepatic arterial infusion chemotherapy (HAIC) for hepatocellular carcinoma (HCC).
Hirohito Osanai, Kazuto Kozaka, Takashi Matsubara, Norihide Yoneda, Takahiro Ogi, Kenichiro Okumura, Atsushi Takamatsu, Azusa Kitao, Shintaro Yagi, Taro Yamashita, Satoshi Kobayashi   +10 more
wiley   +1 more source

Dynamic Images for Prediction of Therapeutic Efficacy of Hepatocellular Carcinoma Treated with Transcatheter Oily Chemoembolization

Journal of the Korean Radiological Society, 2000
Purpose: To predict the therapeutic efficacy of transcatheter oily chemoembolization(TOCE) in the treatment Materials and Methods: We reviewed the findings of 24 dynamic CT or MR scans examined for the purpose of diagnosis before TOCE, and follow-up CT scans obtained after this procedure.
Tae Yong Moon, Chang Won Kim, Hoon Sik Jung, Suck Hong Lee   +3 more
openaire   +1 more source

Targeting Spatiotemporal Heterogeneity of oncomiRNAs: A New Frontier in Cancer Therapy

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background miRNAs are short RNA transcripts that modulate gene expression after transcription and have emerged as pivotal regulators of cancer biology. A subset, termed oncomiRNAs, functions as oncogenes or tumor suppressors, influencing key cellular events such as cell growth, programmed cell death, neovascularization, tissue invasion, and ...
T. Jeethy Ram, Muralee Damodaran
wiley   +1 more source

ATP7A Orchestrates Tumor Progression and Cuproptosis in Hepatocellular Carcinoma via the LINC02038‐miR‐506‐3p Regulatory Circuit

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
In hepatocellular carcinoma (HCC), upregulated LINC02038 acts as a competing endogenous RNA (ceRNA) that sponges tumor‐suppressive miR‐506‐3p, leading to derepression of ATP7A expression. Elevated ATP7A subsequently promotes HCC cell proliferation, migration, and invasion, while simultaneously modulating cuproptosis sensitivity. ABSTRACT Hepatocellular
Zhe Liu, Weixi Shan, Wenyu Zhou, Meiying Long, Long Yang   +4 more
wiley   +1 more source

Management of Satellite Lesions in Hepatocellular Carcinoma: An Updated Review

Journal of Surgical Oncology, Volume 134, Issue 2, Page 157-165, August 2026.
ABSTRACT Satellite lesions, defined as microscopic or small macroscopic tumor nodules within 2 cm of a primary hepatocellular carcinoma (HCC), represent early intrahepatic dissemination and are strongly associated with aggressive tumor biology.
Andy Tran, Mohammed O. Suraju, Ihuoma Tasie, Abdelrahman K. Abdalla, Hassan Aziz   +4 more
wiley   +1 more source

Therapeutic Effect of Transarterial Chemoembolization in Hepatocellular Carcinoma [PDF]

The Ewha Medical Journal, 1991
Jeong Soo Suh, Il Hwan Moon
openaire   +1 more source

Elevated SLC1A5 associated with poor prognosis and therapeutic resistance to transarterial chemoembolization in hepatocellular carcinoma

Journal of Translational Medicine
Abstract Background Hepatocellular carcinoma (HCC) is a common malignant tumor, and glutamine is vital for tumor cells. The role of glutamine transporter SLC1A5 in tumor progression and transarterial chemoembolization (TACE) efficacy is under study.
Guixiong Zhang, Yitai Xiao, Jizhou Tan, Hang Liu, Wenzhe Fan, Jiaping Li   +5 more
openaire   +3 more sources