Results 111 to 120 of about 62,056 (139)

The allergy‐associated chemokine receptors CCR3 and CCR5 can be inactivated by the modified chemokine NNY‐CCL11

Allergy, 2006
Background: CC chemokine ligand 11 (CCL11) is the outstanding member of all described CC chemokine receptor 3 (CCR3) ligands and is shown to be selective for this receptor. However, it also activates CCR5 but only in the micromolar range. Thein vivoactivity of CCL11 is expected to be temporally restricted, as it is degraded by specific proteases such ...
J, Manns, S, Rieder, S, Escher, B, Eilers, W-G, Forssmann, J, Elsner, U, Forssmann   +6 more
openaire   +3 more sources

The chemokines CCL11, CCL20, CCL21, and CCL24 are preferentially expressed in polarized human secondary lymphoid follicles

The Journal of Pathology, 2004
AbstractChemokines regulate cellular trafficking to and from lymphoid follicles. Here, the distribution pattern of four CCL chemokines is defined by in situ hybridization in human lymphoid follicles from tonsils and lymph nodes (LNs) of newborns and adults. Cells expressing CCL11 (eotaxin) and CCL20 (Exodus) were preferentially located within follicles,
Buri, Caroline, Gutersohn, Andreas, Hauser, Chantal, Kappeler, Andreas, Müller, Christoph   +4 more
openaire   +5 more sources

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Differentiation of Patients with Leprosy from Non-Infected Individuals by the Chemokine Eotaxin/CCL11

American Journal of Tropical Medicine and Hygiene, 2007
Diagnosis of leprosy is usually made clinically and there are no tests available for the routine laboratory diagnosis of the disease. The aim of this study was to investigate the potential role of chemokines as biologic markers of disease activity. We used an enzyme-linked immunosorbent assay to measure chemokines in plasma of patients with leprosy (LE)
Vanessa Mendonça, Mauro M Teixeira
exaly   +3 more sources

Serum Levels of the CC Chemokines CCL2, CCL5, and CCL11 in Food Allergic Children with Different Clinical Manifestations

Inflammation, 2012
Food allergies (FA) are frequent in 8 % of children under 3 years old and approximately 2 % of adults. Chemokine are involved in various allergies such as FA. The present study was aimed to determine CCL2, CCL5, and CCL11 levels in FA. The study population of this cross-sectional study contained 63 patients suffering from FA and 100 healthy controls ...
Hossein Khorramdelazad, Houshang Rafatpanah, Reza Vazirinejad   +2 more
exaly   +3 more sources

Clinical utility of circulating matrix metalloproteinase-7 (MMP-7), CC chemokine ligand 18 (CCL18) and CC chemokine ligand 11 (CCL11) as markers for diagnosis of epithelial ovarian cancer

Medical Oncology, 2009
Ovarian cancer remains a highly lethal disease. The aim of the present study was to evaluate the usefulness of measuring serum matrix metalloproteinase-7 (MMP-7), CC chemokine ligand 18 (CCL18) and CC chemokine ligand 11 (CCL11) in comparison with serum cancer antigen 125 (CA 125) for diagnosis of epithelial ovarian cancer (EOC). This study included 51
Samir Zohny
exaly   +3 more sources

Abstract 18998: Deletion of the Duffy Antigen Receptor for Chemokines Impairs Blood Flow Recovery in the Mouse Hindlimb Ischemia Model: Role of CCL11

Circulation, 2023
Introduction: Peripheral Artery Disease (PAD) is characterized by obstruction of the arteries in the lower extremities. Impaired angiogenesis plays a major role in the progression of PAD. Pro-angiogenic and anti-angiogenic chemokines are modulated by binding to the Duffy antigen receptor for chemokines (DARC), a non-signaling ...
Ghaith Aboud, Ragheb Harb, David Kim, Brandee Goo, Mourad OGBI, Praneet Veerapaneni, Ronnie Chouhaita, Philip Coffey, Richard Lee, Yali Hou, Avirup Guha, Hong Shi, Masuko Ushio-Fukai, Brian H Annex, Ha Won Kim, Neal L Weintraub   +15 more
openaire   +1 more source

Blackcurrant anthocyanins modulate CCL11 secretion and suppress allergic airway inflammation

Molecular Nutrition and Food Research, 2017
CCL11, a chemokine, is linked to the early development of airways eosinophilia in allergic asthma. Therefore, CCL11 production is a target for abrogating eosinophilic-driven airway inflammation.
Tafadzwa Nyanhanda, Odette Shaw, Roger Hurst   +2 more
exaly   +2 more sources

Expression of chemokines CCL5 and CCL11 by smooth muscle tumor cells of the uterus and its possible role in the recruitment of mast cells

Gynecologic Oncology, 2007
Smooth muscle tumors of uterus have been reported to contain considerable number of mast cells, especially cellular leiomyoma. However, to our knowledge the mechanism by which mast cells increased in them is not known. The purpose of this study was to reveal the different mast cell subsets in smooth muscle tumors of uterus and to investigate the ...
Xue-Qiong, Zhu, Jie-Qiang, Lv, Yi, Lin, Mei, Xiang, Bao-Hui, Gao, Yi-Fu, Shi   +5 more
openaire   +2 more sources

Emerging Roles of C-C Motif Ligand 11 (CCL11) in Cancers and Liver Diseases: Mechanisms and Therapeutic Implications

International Journal of Molecular Sciences
C-C motif ligand 11 (CCL11) is a multifunctional chemokine that regulates immunity, angiogenesis, and tissue remodeling. In addition to its allergic inflammation role, CCL11 exhibits context-dependent dual functions in relation to cancer progression.
Kwan Man, Ng Kt
exaly   +2 more sources

The C-C motif chemokine ligands CCL5, CCL11, and CCL24 induce the migration of circulating fibrocytes from patients with severe asthma

Mucosal Immunology, 2013
The C-C motif chemokine ligand 5 (CCL5), CCL11, and CCL24 are involved in the pathogenesis of asthma, and their function is mainly associated with the airway recruitment of eosinophils. This study tested their ability to induce the migration of circulating fibrocytes, which may contribute to the development of irreversible airflow obstruction in severe
M, Isgrò, L, Bianchetti, M A, Marini, A, Bellini, M, Schmidt, S, Mattoli   +5 more
openaire   +2 more sources