Results 281 to 290 of about 189,065 (308)
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The Chemokines CXCL10 and XCL1 Recruit Human Annulus Fibrosus Cells
Spine, 2012Human annulus fibrosus tissue and cells were analyzed for the presence of chemokine receptors and the migratory effect of selected chemokines.To investigate spontaneous repair mechanisms and underlying cell recruitment in response to annular tears and degenerative defects.Resorption of herniated disc tissue and the attempt to close annulus tears with ...
Aldemar A, Hegewald +7 more
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Serum α-Chemokine CXCL10 and β-Chemokine CCL2 Levels in HCV-Positive Cryoglobulinemia
2011Chemokines are a group of low-molecular-weight peptides that induce the recruitment of leukocytes to sites of inflammation. Among the four major families, CXC chemokines, with CXCL10 as the prototype, display a strong chemo-attractant activity for Th1 lymphocytes and is a reliable marker of Th1-immune mediated diseases.
ANTONELLI, ALESSANDRO +7 more
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The CXCR3 Binding Chemokine IP-10/CXCL10: Structure and Receptor Interactions
Biochemistry, 2002The structure of IP-10 was solved by NMR spectroscopy and represents the first structure from the class of agonists toward the receptor CXCR3. CXCR3 binding chemokines are unique in their ability to bind receptors from both the CC and CXC classes of chemokine receptors.
Valerie, Booth +4 more
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Inflammatory Bowel Diseases, 2005
Background: Colitis in interleukin (IL)‐10−/− mice is a CD4+ T helper 1 (TH1)‐mediated disease characterized by intermittent, transmural inflammation reminiscent of human Crohn's disease.
J. Hyun +11 more
semanticscholar +1 more source
Background: Colitis in interleukin (IL)‐10−/− mice is a CD4+ T helper 1 (TH1)‐mediated disease characterized by intermittent, transmural inflammation reminiscent of human Crohn's disease.
J. Hyun +11 more
semanticscholar +1 more source
European Journal of Neurology, 2001
Studies of chemokines in cerebrospinal fluid (CSF) of patients with active multiple sclerosis (MS) have indicated that specific chemokines may have important roles in disease pathogenesis. We previously reported that CSF concentrations of CXCL10 (previously known as IP‐10) were elevated in MS patients in relapse, whilst levels of CCL2 (MCP‐1) were ...
Sørensen, Torben Lykke +4 more
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Studies of chemokines in cerebrospinal fluid (CSF) of patients with active multiple sclerosis (MS) have indicated that specific chemokines may have important roles in disease pathogenesis. We previously reported that CSF concentrations of CXCL10 (previously known as IP‐10) were elevated in MS patients in relapse, whilst levels of CCL2 (MCP‐1) were ...
Sørensen, Torben Lykke +4 more
openaire +2 more sources
Chemokines in Vitiligo Pathogenesis: CXCL10 and 12.
The Journal of clinical and aesthetic dermatologyVitiligo is a common pigmentary disease that affects 0.5% to 1% of the global population. The main manifestation of vitiligo is skin depigmentation, which significantly influences appearance and brings enormous psychological stress for patients. C-X-C motif chemokine ligand 9 (CXCL9), CXCL10 , CXCL11 and CXCL12 are linked to the Th1 pattern and have ...
Khaled, Gharib +2 more
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The role of chemokines CXCL10 and CXCL12 in the pathogenesis of vitiligo
Zagazig University Medical Journal, 2020Hend GadAlla +2 more
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