Results 221 to 230 of about 240,302 (314)

C-C chemokine receptor type 5 activation stimulates adipocyte differentiation through ERK-dependent pathway. [PDF]

Int J Med Sci
Chen LK, Chen CW, Wu SY, Liu SY, Wu LY, Chang CJ, Sy LB, Juan CC.   +7 more
europepmc   +1 more source

Chemokines and chemokine receptors coordinate the inflammatory immune response in human cutaneous leishmaniasis

, 2010
Ana Paula Campanelli, Cláudia Brodskyn, Viviane Boaventura, Claire Silva, Ana Maria Ferreira Roselino, Jackson M. L. Costa, Ana Cristina R. Saldanha, Luiz Antônio Rodrigues de Freitas, Camila I. de Oliveira, Manoel Barral‐Netto, João S. Silva, Aldina Barral   +11 more
openalex   +2 more sources

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Multicystic Interstitial Lung Disease Due to a Novel Biallelic C-C Chemokine Receptor Type 2 Variant. [PDF]

Pediatr Pulmonol
Herkner M, Rapp C, Graeber SY, Marx C, Rambuscheck C, Reu-Hofer S, Emiralioglu N, Kiper N, Gilea AI, Notaroberto I, Baruffini E, Temmesfeld-Wollbrück B, Klein C, Wen H, Stahl M, Griese M, Gothe F.   +16 more
europepmc   +1 more source

Regulatable C-X-C chemokine receptor type 4 in iPSC-derived NK cells improves bone marrow chemotaxis and targeting resident tumor

Xiangjun He, Lin-Qin Wang, Wen Zeng, Yiyun Wang, Nian Chen, Peng Yang, Aijun Ti, Qi Zhang, Yuxuan Shao, Mengyan Wang, Zihan Huang, Xueyan Zhang, Mengqi Xu, Lingmin Liang, Xinye Wang, Xiaohui Ding, Tingting Zhu, Peng Zhang, Ziyi Pan, Fei Yang, Yixuan Zhou, Guolong Mo, Jiabiao Hu, Yanan Yue, Jiapan Hu, Yujie Deng, Tony W. Ho, George M. Church, Yongxian Hu, He Huang, Luhan Yang   +30 more
openalex   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Atypical activation and molecular glue-like dimerization mechanism of an intrinsically-biased chemokine receptor

Banerjee N, Ganguly M, Reyaz A, Mishra S, Dalal A, Guo X, Qiu X, Meyrath M, Palmer CB, Guo H, Song S, Sinha S, Roy N, Mukherjee D, Tiwari D, Yadav MK, Chevigne A, Robinson CV, Chen X, Banerjee R, Shukla AK.   +20 more
europepmc   +1 more source

Hsa-miR-100-5p promotes the development and progression of gastric cancer through targeted atypical chemokine receptor 3. [PDF]

Int J Clin Exp Pathol
Wang XL, Jiang JC, Song JY, Ni JY, Song L, Xiao JZ, Fu D, Chen ZY, Cao YF.   +8 more
europepmc   +1 more source

Chemokine Receptor Ccr6 Deficiency Alters Hepatic Inflammatory Cell Recruitment and Promotes Liver Inflammation and Fibrosis

, 2015
Silvia Affò, Daniel Rodrigo‐Torres, Delia Blaya, Oriol Morales‐Ibanez, Mar Coll, Cristina Millán, José Altamirano, Vicente Arroyo, Joan Caballería, Ramón Bataller, Pere Ginès, Pau Sancho‐Bru   +11 more
openalex   +2 more sources

Safety and Efficacy of Adoptive Transfer of Stem Cell Memory Enriched Virus Specific T Cells against CMV and EBV

Advanced Science, EarlyView.
This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao, Xu‐Ying Pei, Yuan‐Yuan Zhang, Juan Xie, Jing‐Wei Tu, Zhuo‐Jun Liu, Yi‐Yang Ding, Chen‐Hua Yan, Yu‐Hong Chen, Yu Wang, Lan‐Ping Xu, Xiao‐Hui Zhang, Xiao‐Jun Huang, Xiang‐Yu Zhao   +13 more
wiley   +1 more source