Results 181 to 190 of about 10,698 (195)
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Evidence of direct interactions between the CC-chemokines CCL3, CCL4 and CCL5 and Leishmania promastigotes.

Molecular and Biochemical Parasitology, 2006
Parasites of the genus Leishmania are very successful parasites, possessing multiple host evasive machineries and unique molecules that aid in their survival. It is presumed that a freshly inoculated parasite needs to survive in the hostile extracellular environment for several hours before it is internalized by a macrophage [1,2].
K. Roychoudhury   +6 more
semanticscholar   +3 more sources

Molecular variants of Leishmania (Viannia) braziliensis trigger distinct patterns of cytokines and chemokines expression in golden hamster.

Molecular Immunology, 2019
Cutaneous leishmaniasis (CL) mainly caused by Leishmania braziliensis is a chronic inflammatory disease widely spread in Brazil. Genetic variant strains of this parasite have been associated with atypical clinical manifestations of CL in an endemic area in Brazil. Furthermore, these strains have presented distinct biological behaviors in golden hamster,
F. Rêgo   +3 more
semanticscholar   +3 more sources

In situ cytokines (IL-4, IL-10, IL-12, IFN-γ) and chemokines (MCP-1, MIP-1α) gene expression in human Leishmania (Leishmania) Mexicana infection.

Cytokine, 2014
Crucial to the defense against Leishmania is the ability of the host to mount a cell-mediated immune response capable of controlling and/or eliminating the parasite. The composition of the cell populations recruited in the early phase of the infection seems to be essential for defining the infection outcomes.
G. Valencia-Pacheco   +6 more
semanticscholar   +3 more sources

Chemokines, natural killer cells and granulocytes in the early course of Leishmania major infection in mice

Medical Microbiology and Immunology, 2001
In the present study the early recruitment of leukocytes into the infected skin and into the draining lymph node (LN) was investigated after subcutaneous infection of mice with Leishmania major promastigotes. Flow cytometric analysis of cells recovered from the infected skin revealed that GR-1+ granulocytes were present as early as 10 h after infection,
K. Müller   +6 more
semanticscholar   +3 more sources

S188 Leishmania major induces secretion of inflammatory cytokines and chemokines by keratinocytes via a TLR2 pathway

International Journal of Antimicrobial Agents, 2007
C. Ronet   +4 more
semanticscholar   +2 more sources

Role of Chemokines in the Pathogenesis of Visceral Leishmaniasis.

Current Medicinal Chemistry, 2022
Visceral leishmaniasis (VL; also known as kala-azar), caused by the protozoan parasite Leishmania donovani is characterized by the inability of the host to generate an effective immune response. The manifestations of the disease depends on involvement of
Ramesh Kumar, M. Bhatia, K. Pai
semanticscholar   +1 more source

Modulation of gene expression profile of cytokines and chemokines following infection with avirulent and virulent Leishmania mexicana

Journal of Pure & Applied Sciences, 2018
الاصابة باللشمانيا الجلدية تحدث نتيجة للاصابة بأنواع من الطفيليات تعود لجنس Leishmania mexicana complex بأنواعها المختلفة، والتي تؤدي الى ظهور تقرحات على جلد الشخص في مكان الاصابة.
Khdija Suleman Mohamed   +1 more
semanticscholar   +1 more source

Reduced expression of the chemokine receptor CCR1 in human macrophages and U-937 cells in vitro infected with Leishmania infantum

Clinical and Experimental Medicine, 2004
Chemokines exert their actions through G-proteinlinked receptors, which are expressed to variable extents by different cell types. In accordance with the chemokine classification, these receptors are designated as CXC, CC, XC, and CX(3)C, followed by R and a number.
PANARO, Maria Antonietta   +7 more
openaire   +3 more sources

A strategic conflict between two sides: host immune cells vs. viral symbiont of Leishmania spp. in cutaneous Leishmaniasis

Brazilian Journal of Health Review
Leishmaniasis comprises a group of neglected tropical diseases that primarily affect regions in the Americas, the Mediterranean basin, the Middle East and central Asia, according to the World Health Organization (WHO).
Ailton Alvaro da Silva   +7 more
semanticscholar   +1 more source

GK1 Improves the Immune Response Induced by Dendritic Cells of BALB/c Mice Infected with Leishmania mexicana Promastigotes

Acta Parasitologica, 2019
Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs), and their capacity to activate the immune response has been widely used in immunotherapies against different diseases, predominantly cancer.
L. Gutiérrez-Kobeh   +1 more
semanticscholar   +1 more source

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