Results 51 to 60 of about 10,698 (195)

Functional diversity of chemokines and chemokine receptors in response to viral infection of the central nervous system. [PDF]

open access: yes, 2006
Encounters with neurotropic viruses result in varied outcomes ranging from encephalitis, paralytic poliomyelitis or other serious consequences to relatively benign infection.
A. Meyer   +108 more
core   +1 more source

Neutrophil-derived CCL3 is essential for the rapid recruitment of dendritic cells to the site of Leishmania major inoculation in resistant mice. [PDF]

open access: yesPLoS Pathogens, 2010
Neutrophils are rapidly and massively recruited to sites of microbial infection, where they can influence the recruitment of dendritic cells. Here, we have analyzed the role of neutrophil released chemokines in the early recruitment of dendritic cells ...
Mélanie Charmoy   +7 more
doaj   +1 more source

Role of IL-33 in inflammation and disease [PDF]

open access: yes, 2011
Interleukin (IL)-33 is a new member of the IL-1 superfamily of cytokines that is expressed by mainly stromal cells, such as epithelial and endothelial cells, and its expression is upregulated following pro-inflammatory stimulation.
Miller, Ashley M.
core   +3 more sources

Repeated exposure to Lutzomyia intermedia sand fly saliva induces local expression of interferon-inducible genes both at the site of injection in mice and in human blood. [PDF]

open access: yes, 2014
During a blood meal, Lutzomyia intermedia sand flies transmit Leishmania braziliensis, a parasite causing tegumentary leishmaniasis. In experimental leishmaniasis, pre-exposure to saliva of most blood-feeding sand flies results in parasite establishment ...
Barral, A.   +7 more
core   +13 more sources

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence-Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis. [PDF]

open access: yesVet Dermatol
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Saridomichelakis MN   +9 more
europepmc   +2 more sources

Pathogen Strategies to Evade Innate Immune Response: A Signaling Point of View [PDF]

open access: yes, 2012
An effective host defense against pathogens requires appropriate recognition of the invading microorganism by immune cells, conducing to an inflammatory process that involves recruitment of leukocytes to the site of infection, activation of ...
Cruz, Maria Teresa   +2 more
core   +2 more sources

Immunity to Lutzomyia intermedia saliva modulates the inflammatory environment induced by Leishmania braziliensis. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2010
BACKGROUND: During blood feeding, sand flies inject Leishmania parasites in the presence of saliva. The types and functions of cells present at the first host-parasite contact are critical to the outcome on infection and sand fly saliva has been shown to
Tatiana R de Moura   +10 more
doaj   +1 more source

Increased CCL-5 (RANTES) Gene Expression in the Choroid Plexus of Dogs with Canine Leishmaniosis

open access: yesAnimals, 2023
Visceral canine leishmaniasis (CanL) can cause several clinical manifestations, including neurological lesions. Few reports have characterized the lesions observed in the central nervous system (CNS) during CanL; however, its pathogenesis remains unclear.
José Eduardo dos Santos Silva   +7 more
doaj   +1 more source

The effects of nitric oxide on the immune system during Trypanosoma cruzi infection [PDF]

open access: yes, 2009
Trypanosoma cruzi infection triggers substantial production of nitric oxide (NO), which has been shown to have protective and toxic effects on the host's immune system.
GUEDES, Paulo MM   +4 more
core   +3 more sources

Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection [PDF]

open access: yes, 2020
Bovine African Trypanosomosis is an infectious parasitic disease affecting livestock productivity and thereby impairing the economic development of Sub-Saharan Africa. The most important trypanosome species implicated is T.
Brys, Lea   +6 more
core   +1 more source

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