Results 61 to 70 of about 72,257 (309)

Development of an interfering peptide M1-20 with potent anti-cancer effects by targeting FOXM1

Cell Death and Disease, 2023
Disrupting protein–protein interactions (PPIs) has emerged as a promising strategy for cancer drug development. Interfering peptides disrupting PPIs can be rationally designed based on the structures of natural sequences mediating these interactions ...
Huitong Bu, Xianling Lan, Haojie Cheng, Chaozhu Pei, Min Ouyang, Yan Chen, Xiaoqin Huang, Li Yu, Yongjun Tan   +8 more
doaj   +1 more source

Accelerate Mass Transport of Proton and Carbon Sources by Super‐Hygroscopic and Porous Nanosheets for Continuous CO2‐To‐Ethylene Upgrade

Advanced Science, EarlyView.
The conceptual diagram of the Tillandsia and a localized enlargement of its leaves. Abstract Gas‐water/catalyst triple‐phase interface and the microenvironment play critical roles in the reaction kinetics and production rate of electrochemical carbon dioxide reduction reactions (CO2RR), which steer concerted proton‐electron transfer steps.
Silong Dong, Guobin Wen, Xinyu Yang, Xiaowen Zhang, Shuxuan Liu, Haoyang Xiong, Yinyi Liu, Kai Zong, Hao Li, Yifan Li, Yi Cui, Bohua Ren, Xin Wang, Mingliang Jin, Zhongwei Chen   +14 more
wiley   +1 more source

Self-Organizing Maps for Exploration of Partially Observed Data and Imputation of Missing Values [PDF]

Chemometrics and Intelligent Laboratory Systems, 2022, 2022
The self-organizing map is an unsupervised neural network which is widely used for data visualisation and clustering in the field of chemometrics. The classical Kohonen algorithm that computes self-organizing maps is suitable only for complete data without any missing values. However, in many applications, partially observed data are the norm.
arxiv  

A synergistic strategy to develop photostable and bright dyes with long Stokes shift for nanoscopy

Nature Communications, 2022
Super-resolution microscopy is a powerful tool for cellular studies but requires bright and stable fluorescent probes. Here, the authors report on a strategy to introduce quinoxaline motifs to conventional probes to make them brighter, more photostable ...
Gangwei Jiang, Tian-Bing Ren, Elisa D’Este, Mengyi Xiong, Bin Xiong, Kai Johnsson, Xiao-Bing Zhang, Lu Wang, Lin Yuan   +8 more
doaj   +1 more source

Lignans: A Chemometric Analysis [PDF]

Molecules, 2018
The physicochemical properties of classical lignans, neolignans, flavonolignans and carbohydrate-lignan conjugates (CLCs) were analysed to assess their ADMET profiles and establish if these compounds are lead-like/drug-like and thus have potential to be or act as leads in the development of future therapeutics.
openaire   +3 more sources

Novel Phosphazenium Tetrafluoroborate Dopant Enables Efficient and Thermally Stable n‐Doped Organic Semiconductors

Advanced Electronic Materials, EarlyView.
A novel n‐dopant, phosphazenium tetrafluoroborate (P2BF4), is introduced for efficient n‐doping in N2200, P(PzDPP‐CT2) and other organic semiconductors (OSCs). P2BF4‐doped OSC films exhibit exceptional thermal stability, maintaining electrical conductivity after heating at > 150 °C for 24 h. This stability allows organic thermoelectric devices based on
Huan Wei, Jing Guo, Heng Liu, Tong Wu, Ping‐An Chen, Chuanding Dong, Shu‐Jen Wang, Stefan Schumacher, Yugang Bai, Ting Lei, Suhao Wang, Yuanyuan Hu   +11 more
wiley   +1 more source

A Robust Functional Partial Least Squares for Scalar-on-Multiple-Function Regression [PDF]

arXiv, 2022
The scalar-on-function regression model has become a popular analysis tool to explore the relationship between a scalar response and multiple functional predictors. Most of the existing approaches to estimate this model are based on the least-squares estimator, which can be seriously affected by outliers in empirical datasets. When outliers are present
arxiv  

A Review on Chemometrics and Climate Change: Insights from Malaysia Case Study

Applied Environmental Research
Climate change consider as main issues and concerns in Malaysia over the decade. Chemometrics techniques have been used in many climate change issues to address the limitations of climate change monitoring studies.
Ismafatin Nabilah Ismail, Mohd Khairul Amri Kamarudin, Wan Nor Azilawanie Tun Ismail, Noorjima Abd Wahab, Ahmad Shakir Mohd Saudi, Mohd Ekhwan Toriman, Firdaus Mohamad Hamzah, Septi Ariadi   +7 more
doaj   +1 more source

Joint selection of wavenumber regions for midir and raman spectra and variables in pls regression using genetic algorithms [PDF]

, 2012
This work fits into the context of cassava processing. Production and consumption of this product is steadily increasing worldwide and especially in tropical regions where, after harvest, cassava starch is extracted according to an empirical process ...
Delarbre, Jean-Louis, Dufour, Dominique, Grosmaire, Lidwine, Maldonado Alvardo, Pedro Gustavo, Reynes, Christelle, Sabatier, Robert, Tran, Thierry   +6 more
core  

A data-driven functional projection approach for the selection of feature ranges in spectra with ICA or cluster analysis [PDF]

, 2008
Prediction problems from spectra are largely encountered in chemometry. In addition to accurate predictions, it is often needed to extract information about which wavelengths in the spectra contribute in an effective way to the quality of the prediction.
Alsberg, Alsberg, Alsberg, Barnes, Benoudjit, C. Krier, Caelen, D. François, F. Rossi, Geladi, Kraskov, M. Verleysen, Mevik, Moody, Pelckmans, R Development Core Team, Ralf, Rossi, Rossi, Rossi, Suykens, Van Dijk, Walczak   +22 more
core   +5 more sources