Results 61 to 70 of about 78,717 (275)
Process Performance Analysis in Large-Scale Systems Integrating Different Sources of Information
, 2012 Process auditing using historical data can identify causes for poor performance and reveal opportunities to improve process operation. To date, the data used has been limited to process measurements; however other sources hold complementary information ...
Bauer +19 more
core +1 more source
General (hetero)polyaryl amine synthesis via multicomponent cycloaromatization of amines
Nature Communications(Hetero)polyaryl amines are extensively prevalent in pharmaceuticals, fine chemicals, and materials but the intricate and varied nature of their structures severely restricts their synthesis. Here, we present a selective multicomponent cycloaromatization
Lebin Su +13 more
doaj +1 more source
A comprehensive review on the applications of chemometrics in analytical chemistry
Journal of Applied Pharmaceutical ResearchBackground: This article presents a review of the various applications of chemometrics in analytical chemistry. Chemometrics is essential to analytical chemistry because it provides sophisticated methods for extracting, analyzing, and interpreting ...
Projesh Saha +3 more
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ADME-Space: a new tool for medicinal chemists to explore ADME properties
Scientific Reports, 2017 We introduce a new chemical space for drugs and drug-like molecules, exclusively based on their in silico ADME behaviour. This ADME-Space is based on self-organizing map (SOM) applied to 26,000 molecules. Twenty accurate QSPR models, describing important
Giovanni Bocci +5 more
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Biotechnology and Bioengineering, EarlyView.ABSTRACT The competition in the biopharmaceutical market is increasing due to the market entry of biosimilars and rising costs in research and development of new drugs. Hence, continuous manufacturing gained significant attention due to its potential in reducing production cycle times and costs, as well as the possibility of real‐time release testing ...
Mariana Carvalho +4 more
wiley +1 more source
Metabolomics : a tool for studying plant biology [PDF]
, 2005 In recent years new technologies have allowed gene expression, protein and metabolite profiles in different tissues and developmental stages to be monitored.
Gullberg, Jonas
core
Regularized Partial Least Squares with an Application to NMR Spectroscopy [PDF]
, 2012 High-dimensional data common in genomics, proteomics, and chemometrics often contains complicated correlation structures. Recently, partial least squares (PLS) and Sparse PLS methods have gained attention in these areas as dimension reduction techniques ...
Allen, Genevera I. +3 more
core +2 more sources
Aggregate, 2023 Due to both the requirements of repeated complex organic synthesis and tedious biochemical verification experiments for the screening of new photosensitizers, the development of a satisfactory photosensitizer with excellent photosensitivity and highly ...
Yingcai Hu +5 more
doaj +1 more source
Biotechnology Progress, EarlyView.Abstract Artificial intelligence and automation are no longer just buzzwords in the biopharmaceutical industry. The manufacturing of a class of biologics, comprising monoclonal antibodies, cell therapies, and gene therapies, is far more complex than that of traditional small molecule drugs.
Shyam Panjwani, Hao Wei, John Mason
wiley +1 more source
Exploration, 2023 The acidic characteristic of the tumor site is one of the most well‐known features and provides a series of opportunities for cancer‐specific theranostic strategies.
Xu Li +5 more
doaj +1 more source