Results 61 to 70 of about 29,943 (226)

Evaluating the Health Economic Impacts of Baloxavir Marboxil and Oseltamivir for the Treatment of Influenza in Adult Outpatients in Hong Kong: A Cost‐Effectiveness Analysis

Influenza and Other Respiratory Viruses, Volume 20, Issue 3, March 2026.
ABSTRACT Background Baloxavir marboxil, an antiviral used only in private hospitals in Hong Kong since February 2019 for treating influenza, is recognized for its efficacy against strains resistant to standard antiviral agents, providing an alternative to neuraminidase inhibitors such as oseltamivir.
Ruohan Chen, Zengyang Shao, Kaiming Bi, Benjamin John Cowling, Zhanwei Du   +4 more
wiley   +1 more source

Schistosomiasis Chemotherapy, Chemoprevention, and Vaccines: History, Progress, and Priorities

Immunity, Inflammation and Disease
Background Schistosomiasis is a major human disease of public health importance. Freshwater snails serving as intermediary hosts and human interaction with surface water tainted by feces or urine are both necessary components of the transmission cycle ...
Alaa Oqalaa E. Alibrahim, Walaa A. Elkholy, Mona M. El‐Derbawy, Noha F. Zahran, Athanasios Alexiou, Marios Papadakis, Gaber El‐Saber Batiha   +6 more
doaj   +1 more source

Whole-blood transcriptomic signatures induced during immunization by chloroquine prophylaxis and Plasmodium falciparum sporozoites [PDF]

, 2019
A highly effective vaccine that confers sterile protection to malaria is urgently needed. Immunization under chemoprophylaxis with sporozoites (CPS) consistently confers high levels of protection in the Controlled Human Malaria infection (CHMI) model. To
Bijker, Else M., Crompton, Peter D., Haks, Mariëlle C., Lorenzi, Hernan, Ottenhoff, Tom H. M., Sauerwein, Robert W., Schats, Remko, Tran, Tuan M., Venepally, Pratap, Visser, Leo   +9 more
core   +2 more sources

Long‐term outcome after allogeneic stem cell transplantation for GATA2 deficiency: An analysis of 67 adults and children from France and Belgium

British Journal of Haematology, Volume 208, Issue 1, Page 250-258, January 2026.
The overall survival of patients receiving an allogeneic haematopoietic stem cell transplant (HSCT) for GATA2 deficiency was significantly better if they were transplanted recently, with a bone marrow or cord blood graft and if the transplant was performed before the onset of excess blast. Excess blast before HSCT was the only factor associated with an
Flore Sicre de Fontbrune, Florian Chevillon, Mony Fahd, Kristell Desseaux, Xavier Poiré, Edouard Forcade, Arthur Sterin, Bénédicte Neven, Virginie Gandemer, Sylvain Thepot, Alice Garnier, Bruno Lioure, Ambroise Marcais, Stephanie Nguyen‐Quoc, Suzanne Tavitian, Laure Vincent, Jean Donadieu, Matthieu Resche Riggon, Sylvie Chevret, Marlene Pasquet, Regis Peffault de Latour   +20 more
wiley   +1 more source

Malaria chemoprophylaxis and the serologic response to measles and diphtheria-tetanus-whole-cell pertussis vaccines

Malaria Journal, 2005
Background Acute malaria has been associated with a decreased antibody response to tetanus and diphtheria toxoids, meningococcal, salmonella, and Hib vaccines.
Saliou Pierre, Lobel Hans O, Collins William E, Meade Bruce D, Manclark Charles R, Breman Joel G, Rosen Jennifer B, Roberts Jacquelin M, Campaoré Pierre, Miller Mark A   +9 more
doaj   +1 more source

PoolSeq Genome‐Wide Association Studies and Microbial Signature Analyses Identify Novel Candidates Associated With Pyrethroid Resistance Evolution in Anopheles funestus in Cameroon

Molecular Ecology, Volume 35, Issue 1, January 2026.
ABSTRACT Intensification of insecticide resistance in malaria vectors is undermining efforts to sustain control strategies. The evolutionary features underlying such exacerbation in major vector such as Anopheles funestus are only partially understood.
Mahamat Gadji, Jonas A. Kengne‐Ouafo, Magellan Tchouakui, Murielle J. Wondji, Leon M. J. Mugenzi, Jack Hearn, Boyomo Onana, Charles S. Wondji   +7 more
wiley   +1 more source

Economics of Malaria Prevention in US Travelers to West Africa [PDF]

, 2013
Background. Pretravel health consultations help international travelers manage travel-related illness risks through education, vaccination, and medication. This study evaluated costs and benefits of that portion of the health consultation associated with
Adachi, Kenji, Arguin, Paul, Brunette, Gary, Coleman, Margaret S, Jentes, Emily S, Khan, Nomana, Knouse, Mark, MD, LaRocque, Regina C, Meltzer, Martin I, Rao, Sowmya R, Ryan, Edward T, Sotir, Mark J   +11 more
core   +1 more source

Cannabis‐Derived Compounds Against Plasmodium sp.: A Systematic Review of Preclinical Studies

Tropical Medicine &International Health, Volume 31, Issue 1, Page 1-9, January 2026.
ABSTRACT Objective This study aims to evaluate preclinical studies on the effects and toxicity of cannabis‐derived compounds against Plasmodium sp. Methods A literature search was conducted in Web of Science, PubMed, Scopus and LILACS databases until December 2024. Studies that assessed the activity or toxicity of cannabis against Plasmodium sp.
Tácio de Mendonça Lima, Luann Wendel Pereira de Sena, Ana Carolina Corrêa de Sousa, Gabriel Rodrigues Martins de Freitas, Inajara Rotta, Marília Berlofa Visacri   +5 more
wiley   +1 more source

Doxycycline Usage for Prevention of Leptospirosis among Farmers and Reasons for Failure to Use Chemoprophylaxis: A Descriptive Study from Southern Sri Lanka

Journal of Tropical Medicine, 2019
Background. Leptospirosis causes substantial morbidity and mortality in Sri Lanka. Health authorities have implemented a chemoprophylaxis programme for prevention of disease for farmers who are at a high risk of leptospirosis.
C. L. Fonseka, B. N. Vidanapathirana, C. M. de Silva, A. A. B. B. Athukorala, P. R. Goonawardena, A. P. Karunathilake, I. H. Rajapakse, A. S. Dissanayake   +7 more
doaj   +1 more source

Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria [PDF]

, 2015
BACKGROUND Sporozoite immunization of animals and humans under a chemo-prophylactic cover of chloroquine (CPS-CQ) efficiently induces sterile protection against malaria.
Bijker, Else M, Cockburn, Ian, Nganou-Makamdop, Krystelle, Sauerwein, Robert W, van Gemert, Geert-Jan, Zavala, Fidel   +5 more
core   +2 more sources