Results 151 to 160 of about 133,417 (336)

Induction chemotherapy with paclitaxel, carboplatin, and cetuximab (PCE) followed by chemoradiotherapy for unresectable locoregional recurrence after curative surgery in patients with squamous cell carcinoma of the head and neck

open access: yesFrontiers in Oncology
BackgroundThe significance of induction chemotherapy (IC) in the treatment of squamous cell carcinoma of the head and neck (SCCHN) with unresectable locoregional recurrence after curative surgery has not been clarified.
Masanobu Sato   +16 more
doaj   +1 more source

A 2-step comprehensive high-dose chemoradiotherapy second-line program for relapsed and refractory Hodgkin disease: analysis by intent to treat and development of a prognostic model [PDF]

open access: bronze, 2001
Craig H. Moskowitz   +18 more
openalex   +1 more source

Osimertinib Cost Minimization in Non‐Small Cell Lung Cancer (NSCLC) Treatment: Hypothesis Generation for a Population Pharmacokinetic Approach for Equivalent Dose Optimization of Osimertinib in Combination With Cobicistat

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Pharmacokinetic boosting can be a strategy to enhance osimertinib exposure and reduce treatment associated costs. The OSIBOOST trial demonstrated that it was feasible to boost low osimertinib plasma trough levels with cobicistat. The current study aims to establish the equivalent dose of cobicistat boosted osimertinib compared to osimertinib ...
Niels Westra   +9 more
wiley   +1 more source

Comprehensive Analysis of Chyle Leak in Resected Pancreatic Head Cancer: Impact on Clinical, Oncologic, and Nutritional Outcomes

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Chyle leak (CL) is a relevant complication of pancreatic surgery, but its incidence, risk factors, clinical and oncologic impacts, and nutritional relevance remain inconsistent and limited. Methods We retrospectively reviewed patients who underwent pancreaticoduodenectomy for pancreatic head cancer from 2007 to 2023 at a single ...
Jae Seung Kwak   +4 more
wiley   +1 more source

The Impact of Intraoperative Radiotherapy on Margin Positive Locally Advanced Rectal Cancer: A Propensity‐Matched Analysis of The National Cancer Database

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Purpose Intraoperative radiotherapy (IORT) is utilized as an adjunctive treatment in advanced rectal cancer, particularly in cases with threatened surgical margins. Although IORT has shown benefits in enhancing local tumor control, its impact on overall survival (OS) remains unclear.
Metincan Erkaya   +8 more
wiley   +1 more source

Induction Chemotherapy Followed by Concurrent Chemoradiotherapy in Locoregional Esophageal Cancer [PDF]

open access: bronze, 2001
Gyeong Won Lee   +12 more
openalex   +1 more source

Rhaponitin Reverses Cisplatin Resistance and Impairs Cancer Stemness Through HIF‐1α/MCT4/Wnt Pathway in Tongue Squamous Cell Carcinoma

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rhaponitin (Rha) possesses anti‐tumor activity and mediates the transcriptional activity of hypoxia‐inducible factor (HIF)‐1α that affects cisplatin (Cis) resistance. However, whether Rha can lessen Cis resistance in tongue squamous cell carcinoma (TSCC) by mediating HIF‐1α activity is unclear. Cis‐resistant SCC9 (SCC9‐CisR) cells were treated
Yuan Wu   +5 more
wiley   +1 more source

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