Nicotinic Acetylcholine Receptor Channels in Cat Chemoreceptor Cells
2003Neurotransmitters are likely to play a key role for hypoxic chemotransmission in the carotid body. Among several neurotransmitters, ACh appears to be a major excitatory neurotransmitter in the cat carotid body (Fitzgerald, 2000). ACh may act directly on the afferent nerve endings and generates action potentials (Hayashida et al., 1980; Zhong & Nurse ...
Tomoko, Higashi +3 more
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Polar Location of the Chemoreceptor Complex in the Escherichia coli Cell
Science, 1993The eukaryotic cell exhibits compartmentalization of functions to various membrane-bound organelles and to specific domains within each membrane. The spatial distribution of the membrane chemoreceptors and associated cytoplasmic chemotaxis proteins in Escherichia coli were examined as a prototypic functional ...
J R, Maddock, L, Shapiro
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Modification of the Glutathione Redox Environment and Chemoreceptor Cell Responses
2006Carotid body (CB) chemoreceptor cells (CBCC) are involved in maintaining the homeostasis of O2 by detecting arterial blood PO2 and become activated when arterial PO2 decreases. In response to hypoxia, CBCC release neurotransmitters which excite the adjacent afferent nerve terminals of the carotid sinus nerve, increase their action potential and, via ...
A, Gómez-Niño +3 more
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Twitching cells use a chemoreceptor to detect bacterial competitors
2022Abstract Bacteria live in cosmopolitan communities, where the ability to sense and respond to interspecies and environmental signals is critical for survival. We previously showed the pathogen Pseudomonas aeruginosa detects secreted peptides from bacterial competitors and navigates ...
Kaitlin D. Yarrington +2 more
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Physiology of chemoreceptor cells in the legs of the freshwater prawn, macrobrachium rosenbergii
Comparative Biochemistry and Physiology Part A: Physiology, 19881. Chemoreceptor cells in the first pereiopods (legs) of the freshwater prawn, Macrobrachium rosenbergii, were investigated using single-unit, extracellular electrophysiological recording techniques on an isolated, perfused leg preparation. 2. The cells were responsive to aqueous extracts of food (shrimp, mullet, trout chow), a salt mixture (artificial
C D, Derby, S, Harpaz
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Multiple Central Chemoreceptor Sites: Cell Types and function in vivo
2008Central chemoreception is a distributed property involving many sites and neuronal types. Focal acidosis in conscious or anesthetized animals at many hindbrain sites stimulates breathing. The steady-state CO2 response in conscious animals is reduced by cell specific lesions of catecholamine, 5HT or neurokinin-1 receptor (NK1R) expressing neurons and by
Gene, Nattie, Aihua, Li
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Oxygen‐Sensitive Potassium Channels in Chemoreceptor Cell Physiology
Annals of the New York Academy of Sciences, 2009The characterization of the molecular mechanisms involved in low‐oxygen chemotransduction has been an active field of research since the first description of an oxygen‐sensitive K+ channel in rabbit carotid body (CB) chemoreceptor cells. As a result, a large number of components of the transduction cascade, from O2 sensors to O2‐sensitive ion channels,
Constancio, Gonzalez +3 more
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Endothelin Modulates Chemoreceptor Cell Function in Mammalian Carotid Body
1996The endothelins (ET-1, ET-2, ET-3), a family of unique 21 amino acid peptides, produce a transient vasodilation and protracted vasoconstriction in numerous vascular beds (see Rubanyi and Polokoff, 1994, for review). The synthesis and release of ETs was first described in cultured vascular endothelial cells, but later studies showed that ETs and ...
L, He +4 more
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Immunocytochemical localization of O2-sensing protein (NADPH oxidase) in chemoreceptor cells
Microscopy Research and Technique, 1997A potential candidate for an oxygen-sensing protein in chemoreceptor cells is a heme-linked multicomponent NADPH oxidase, originally described in neutrophils. The postulated function for the oxidase in chemoreceptor cells is to signal changes in oxygen levels (either in the blood or in the airway lumen) via changes in oxygen metabolite production.
C, Youngson +6 more
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Peripheral Filters and Chemoreceptor Cells in Fishes
1988Olfaction in vertebrates is the sense used in the processing of chemical information that is detected and transmitted to the central nervous system by bipolar neurons that compose the olfactory nerve (cranial nerve I). Gustation is the sense used in the processing of chemical information that is detected by taste cells and transmitted centrally by ...
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