Results 231 to 240 of about 14,150 (254)
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Twitching cells use a chemoreceptor to detect bacterial competitors
2022AbstractBacteria live in cosmopolitan communities, where the ability to sense and respond to interspecies and environmental signals is critical for survival. We previously showed the pathogenPseudomonas aeruginosadetects secreted peptides from bacterial competitors and navigates interspecies signal gradients using pilus-based motility. Yet, it remained
Kaitlin D. Yarrington +2 more
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Nicotinic Acetylcholine Receptor Channels in Cat Chemoreceptor Cells
2003Neurotransmitters are likely to play a key role for hypoxic chemotransmission in the carotid body. Among several neurotransmitters, ACh appears to be a major excitatory neurotransmitter in the cat carotid body (Fitzgerald, 2000). ACh may act directly on the afferent nerve endings and generates action potentials (Hayashida et al., 1980; Zhong & Nurse ...
Tomoko, Higashi +3 more
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Immunocytochemical localization of O2-sensing protein (NADPH oxidase) in chemoreceptor cells
Microscopy Research and Technique, 1997A potential candidate for an oxygen-sensing protein in chemoreceptor cells is a heme-linked multicomponent NADPH oxidase, originally described in neutrophils. The postulated function for the oxidase in chemoreceptor cells is to signal changes in oxygen levels (either in the blood or in the airway lumen) via changes in oxygen metabolite production.
C, Youngson +6 more
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Oxygen‐Sensitive Potassium Channels in Chemoreceptor Cell Physiology
Annals of the New York Academy of Sciences, 2009The characterization of the molecular mechanisms involved in low‐oxygen chemotransduction has been an active field of research since the first description of an oxygen‐sensitive K+ channel in rabbit carotid body (CB) chemoreceptor cells. As a result, a large number of components of the transduction cascade, from O2 sensors to O2‐sensitive ion channels,
Constancio, Gonzalez +3 more
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Oxygen Sensing and the Electrophysiology of Arterial Chemoreceptor Cells
Physiology, 1993The carotid bodies sense reductions in arterial oxygen tension (PO2) and stimulate the respiratory center to induce hyperventilation. Lowering PO2, detected by O2-sensitive K+ channels, evokes a selective inhibition of the K+ current of glomus cells, with an increase of cellular excitability and cytosolic Ca2+.
J Lopez-Barneo, AR Benot, J Urena
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Evolution of Taste and Solitary Chemoreceptor Cell Systems
Brain, Behavior and Evolution, 1997Vertebrates possess four distinct chemosensory systems distinguishable on the basis of structure, innervation and utilization: olfaction, taste, solitary chemoreceptor cells (SCC) and the common chemical sense (free nerve endings). Of these, taste and the SCC sense rely on secondary receptor cells situated in the epidermis and synapsing on sensory ...
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Endothelin Modulates Chemoreceptor Cell Function in Mammalian Carotid Body
1996The endothelins (ET-1, ET-2, ET-3), a family of unique 21 amino acid peptides, produce a transient vasodilation and protracted vasoconstriction in numerous vascular beds (see Rubanyi and Polokoff, 1994, for review). The synthesis and release of ETs was first described in cultured vascular endothelial cells, but later studies showed that ETs and ...
L, He +4 more
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Modification of the Glutathione Redox Environment and Chemoreceptor Cell Responses
2006Carotid body (CB) chemoreceptor cells (CBCC) are involved in maintaining the homeostasis of O2 by detecting arterial blood PO2 and become activated when arterial PO2 decreases. In response to hypoxia, CBCC release neurotransmitters which excite the adjacent afferent nerve terminals of the carotid sinus nerve, increase their action potential and, via ...
A, Gómez-Niño +3 more
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Characterization of cultured chemoreceptor cells dissociated from adult rabbit carotid body
American Journal of Physiology-Cell Physiology, 1992Short-term cell cultures were obtained from enzymatically dissociated carotid bodies from adult rabbits, and morphological and functional characterization of the cultured chemoreceptor cells were carried out. Under phase contrast, freshly isolated type I cells are round, bright, and 10-14 microns in diameter and exhibit strong fluorescence when ...
M T, Pérez-García +4 more
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Acetylcholine Increases Intracellular Calcium of Arterial Chemoreceptor Cells of Adult Cats
Journal of Neurophysiology, 1997Shirahata, Machiko, Robert S. Fitzgerald, and James S. K. Sham. Acetylcholine increases intracellular calcium of arterial chemoreceptor cells of adult cats. J. Neurophysiol. 78: 2388–2395, 1997. Several neurotransmitters have been reported to play important roles in the chemoreception of the carotid body.
M, Shirahata, R S, Fitzgerald, J S, Sham
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