Results 41 to 50 of about 2,884 (163)
Mouse TRPA1 function and membrane localization are modulated by direct interactions with cholesterol
eLife, 2019 The cation channel TRPA1 transduces a myriad of noxious chemical stimuli into nociceptor electrical excitation and neuropeptide release, leading to pain and neurogenic inflammation.
Justyna B Startek +9 more
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Recent Advances in Gut Nutrient Chemosensing [PDF]
Current Medicinal Chemistry, 2012 The field of gut nutrient chemosensing is evolving rapidly. Recent advances have uncovered the mechanism by which specific nutrient components evoke multiple metabolic responses. Deorphanization of G protein-coupled receptors (GPCRs) in the gut has helped identify previously unliganded receptors and their cognate ligands.
C A, Nguyen, Y, Akiba, J D, Kaunitz
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A host beetle pheromone regulates development and behavior in the nematode Pristionchus pacificus
eLife, 2014 Nematodes and insects are the two most speciose animal phyla and nematode–insect associations encompass widespread biological interactions. To dissect the chemical signals and the genes mediating this association, we investigated the effect of an ...
Jessica K Cinkornpumin +7 more
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Chemosensation in anxiety: the trigeminal system matters
Chemical Senses, 2022 AbstractThe presence of a perceptual bias due to anxiety is well demonstrated in cognitive and sensory task for the visual and auditory modality. Event-related potentials, by their specific measurement of neural processes, have strongly contributed to this evidence.
Olivier Fortier-Lebel +3 more
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From chemosensing in microorganisms to practical biosensors [PDF]
Physical Review E, 2012 Microorganisms like bacteria can sense concentration of chemo-attractants in its medium very accurately. They achieve this through interaction between the receptors on their cell surface and the chemo-attractant molecules (like sugar). But the physical processes like diffusion set some limits on the accuracy of detection which was discussed by Berg and
GHOSH, SK, KUNDU, T, SAIN, A
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New Plant Protection, EarlyView.We identified and characterized the gustatory and ionotropic receptors of Cydia pomonella using transcriptomics and in silico approaches, linking candidate sugar receptors to larval feeding attraction. Functional assays and behavioral tests highlighted isoquercitrin as a key feeding stimulant, providing a foundation for olfactory‐ and taste‐based pest ...
Chenyun Ding +6 more
wiley +1 more source
Deciphering the chemical language of inbred and wild mouse conspecific scents
eLifeIn most mammals, conspecific chemosensory communication relies on semiochemical release within complex bodily secretions and subsequent stimulus detection by the vomeronasal organ (VNO).
Maximilian Nagel +8 more
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Sensory Neuroscience, EarlyView.This schematic highlights GPCRs as the central hub of olfactory signaling in health and disease. The central GPCR shows odorant activation and downstream pathways. Surrounding quadrants illustrate four GPCR‐mediated themes: odor perception and adaptation, mucosal immunity and regeneration, memory consolidation via neural circuits, and GPCR‐related ...
Zishuo Guo +11 more
wiley +1 more source
The Two Main Olfactory Receptor Families in Drosophila, ORs and IRs: A Comparative Approach
Frontiers in Cellular Neuroscience, 2018 Most insect species rely on the detection of olfactory cues for critical behaviors for the survival of the species, e.g., finding food, suitable mates and appropriate egg-laying sites.
Carolina Gomez-Diaz +3 more
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Not Only COVID-19: Involvement of Multiple Chemosensory Systems in Human Diseases
Frontiers in Neural Circuits, 2022 Chemosensory systems are deemed marginal in human pathology. In appraising their role, we aim at suggesting a paradigm shift based on the available clinical and experimental data that will be discussed.
Antonio Caretta +3 more
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