Results 51 to 60 of about 2,884 (163)

Diving Deeper Into Mechanisms of Acrylamide‐Induced Toxicity: RNA Sequencing Reveals Transcriptomic Alteration and Retrotransposon Expression in Drosophila melanogaster

Environmental Toxicology, EarlyView.
ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye, Titilayomi Ayomide Otenaike, Daniela Moreira Mombach, Monica Medeiros Silva, Amos Olalekan Abolaji, Elgion Lucio Da Silva Loreto   +5 more
wiley   +1 more source

Gut chemosensing: implications for disease pathogenesis [PDF]

F1000Research, 2016
The ability of humans to sense chemical signals in ingested substances is implicit in the ability to detect the five basic tastes; sweet, sour, bitter, salty, and umami. Of these, sweet, bitter, and umami tastes are detected by lingual G-protein-coupled receptors (GPCRs). Recently, these receptors were also localized to the gut mucosa.
Christopher J. Berg, Jonathan D. Kaunitz
openaire   +4 more sources

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Genome and transcriptome‐based identification and expression profiling of chemosensory gene families across developmental stages and tissues in Sirex noctilio (Hymenoptera: Siricidae)

Insect Molecular Biology, EarlyView.
The first draft genome of Sirex noctilio was produced. Fifteen S. noctilio transcriptomes were sequenced to study chemosensory gene expression patterns. SnocOR16 and SnocSNMP1 displayed tissue‐ and sex‐specific expression patterns. Abstract The Sirex woodwasp (Sirex noctilio; Hymenoptera: Siricidae) is among the most destructive invasive pests ...
Alisa Postma, Leandri Klynsmith, Tuan A. Duong, Jeremy Dean Allison, Werner Smidt, Robert M. Waterhouse, Peter Lesny, Jan Philip Oeyen, Malte Petersen, Sebastian Martin, Shanlin Liu, Xin Zhou, Tanja Ziesmann, Alexander Donath, Christoph Mayer, Bernhard Misof, Oliver Niehuis, Ralph S. Peters, Lars Podsiadlowski, Martin P. A. Coetzee, Fourie Joubert, Bernard Slippers   +21 more
wiley   +1 more source

Evolution of five environmentally responsive gene families in a pine‐feeding sawfly, Neodiprion lecontei (Hymenoptera: Diprionidae)

Ecology and Evolution, 2023
A central goal in evolutionary biology is to determine the predictability of adaptive genetic changes. Despite many documented cases of convergent evolution at individual loci, little is known about the repeatability of gene family expansions and ...
Kim L. Vertacnik, Danielle K. Herrig, R. Keating Godfrey, Tom Hill, Scott M. Geib, Robert L. Unckless, David R. Nelson, Catherine R. Linnen   +7 more
doaj   +1 more source

Chemosensation: Tasting with the Tail [PDF]

Current Biology, 2002
Animals employ multiple mechanisms to detect the presence and location of environmental stimuli. Recent work suggests that Caenorhabditis elegans uses chemosensory information provided by spatially distinct sensilla to generate a sensory map of its environment and to avoid noxious compounds.
openaire   +2 more sources

Luminal chemosensing in the duodenal mucosa [PDF]

Acta Physiologica, 2010
AbstractThe upper gastrointestinal (GI) mucosa is exposed to endogenous and exogenous chemicals, including gastric acid, CO2 and nutrients. Mucosal chemical sensors are necessary to exert physiological responses such as secretion, digestion, absorption and motility.
Y, Akiba, J D, Kaunitz
openaire   +2 more sources

Mosquito and arbovirus surveillance in wetlands of South‐East England: Comparison of two adult mosquito traps, use of a novel trap with FTA™ cards and arbovirus testing

Medical and Veterinary Entomology, EarlyView.
Trap performance: Mosquito Magnet® captured significantly more mosquitoes overall, while BG‐Sentinel showed greater species evenness and was more effective for Culex pipiens s.l. and broader species representation. Spatial variation: Mosquito abundance and species composition varied significantly between wetlands, highlighting the importance of site ...
Alexander G. C. Vaux, Harrison Hardy, Lucy Crossley, Colin J. Johnston, Anthony J. Abbott, Stephen Findlay‐Wilson, Amanda Callaghan, Jolyon M. Medlock   +7 more
wiley   +1 more source

Spatial-temporal dynamics of collective chemosensing [PDF]

Proceedings of the National Academy of Sciences, 2012
Although the process of chemosensing by individual cells is intrisically stochastic, multicellular organisms exhibit highly regulated responses to external stimulations. Two key elements to understand the deterministic features of chemosensing are intercellular communications and the role of pacemaker cells.
Bo, Sun, Josephine, Lembong, Valery, Normand, Matthew, Rogers, Howard A, Stone   +4 more
openaire   +2 more sources

Molecular bases of insect odorant receptor function: specificity and evolution

Biological Reviews, Volume 101, Issue 2, Page 1036-1049, April 2026.
ABSTRACT Insect odorant receptors (ORs) are a class of chemoreceptors that insects use to detect volatile cues in their environment. In recent years, major advances in the field of structural biology have made it possible to obtain the first structures of insect ORs.
Zibo Li, Abhinob Baruah, Sridevi Bhamidipati, Nicolas Montagné, Emmanuelle Jacquin‐Joly, Camille Meslin   +5 more
wiley   +1 more source