Results 111 to 120 of about 23,045 (211)

Family Size Evolution in Drosophila Chemosensory Gene Families: A Comparative Analysis with a Critical Appraisal of Methods [PDF]

, 2014
Gene turnover rates and the evolution of gene family sizes are important aspects of genome evolution. Here, we use curated sequence data of the major chemosensory gene families from Drosophila-the gustatory receptor, odorant receptor, ionotropic receptor,
Akaike, Alejandro Sánchez-Gracia, Almeida, Benton, Clark, Croset, De Bie, Demuth, Dufayard, Dumas, Engsontia, Fortna, Francisca C. Almeida, Frickey, Gabaldon, Gardiner, Goodman, Guo, Hahn, Hahn, Hallinan, Jose Luis Campos, Julio Rozas, Katoh, Kondrashov, Kulathinal, Librado, Lynch, McBride, McBride, McLysaght, Nakagawa, Nei, Nei, Nei, Nei, Obbard, Ohno, Ohta, Ohta, Ohta, Oliveira, Osada, Pegueroles, Pelosi, Petes, Peñalva-Arana, Pollard, Rasmussen, Rio, Robertson, Robertson, Rubin, Sato, Sawyer, Silbering, Smadja, Stamatakis, Stensmyr, Suyama, Swanson, Sánchez-Gracia, Tamura, Tegoni, Vieira, Vieira, Yang, Yang   +67 more
core   +2 more sources

Transcriptomic and DNA Methylation Profiles of Alternative Aphid Morphs and Genotypes

Ecology and Evolution, Volume 16, Issue 5, May 2026.
Graph showing the correlation between differentially expressed genes and differentially methylated genes. There is no correlation between gene expression and DNA methylation level in pea aphid polyphenism. ABSTRACT Pea aphids can develop alternative morphs when exposed to stressful conditions, showing differences between genotypes in their stress ...
Zhe Yang Yim, Christopher Murgatroyd, Reinmar Hager   +2 more
wiley   +1 more source

Chemosensorial G-proteins-Coupled Receptors: A Perspective from Computational Methods

, 2013
G-protein coupled receptors (GPCRs) constitute the targets of about 40 % of all the pharmaceutical drugs in the market and, among other functions, a large portion of the family detects odorants and a variety of tastant molecules. Computational techniques are instrumental to understand structure, dynamics and function of the cascades triggered by these ...
MUSIANI, FRANCESCO, Rossetti, Giulia, Giorgetti, Alejandro, Carloni, Paolo   +3 more
openaire   +2 more sources

Identification and Expression Profiles of Chemosensory Genes in the Antennal Transcriptome of Protaetia brevitarsis (Coleoptera: Scarabaeidae)

Insects
Chemosensory systems play a pivotal role in insect survival and reproduction by mediating the detection of volatile organic compounds in the environment. Protaetia brevitarsis (Coleoptera: Scarabaeidae), a phytophagous pest widely distributed across East
Shi-Hang Zhao, Yang Yue, Qi Gao, Rui-Tao Yu, Zhao-Hui Yang, Nan Zhou, Guo-Liang Xu   +6 more
doaj   +1 more source

Using a Robust and Sensitive GFP-Based cGMP Sensor for Real-Time Imaging in Intact Caenorhabditis elegans. [PDF]

, 2019
cGMP plays a role in sensory signaling and plasticity by regulating ion channels, phosphodiesterases, and kinases. Studies that primarily used genetic and biochemical tools suggest that cGMP is spatiotemporally regulated in multiple sensory modalities ...
Ali, Nebat, Andersen, Kristine, Barsi-Rhyne, Benjamin, Brueggemann, Chantal, Costa, Wagner Steuer, Ferkey, Denise M, Futey, Mary, Gottschalk, Alexander, Hamilton, O Scott, Hill, Tyler, Krzyzanowski, Michelle C, L'Etoile, Noelle, Li, Joy, Mitchell, Jordan, Nagpal, Jatin, Schneider, Martin W, Sengupta, Piali, Shankar, Raakhee, Tran, Alan, VanHoven, Miri, Varshney, Aruna, Woldemariam, Sarah, Yu, Yanxun V   +22 more
core  

Mechanisms by which sialylated milk oligosaccharides impact bone biology in a gnotobiotic mouse model of infant undernutrition [PDF]

, 2019
Undernutrition in children is a pressing global health problem, manifested in part by impaired linear growth (stunting). Current nutritional interventions have been largely ineffective in overcoming stunting, emphasizing the need to obtain better ...
Ahern, Philip P., Ahmed, Tahmeed, Barile, Daniela, Barratt, Michael J., Cheng, Jiye, Cowardin, Carrie A., Gordon, Jeffrey I., Guruge, Janaki L., Head, Richard D., Hibberd, Matthew C., Huq, Sayeeda, Kung, Vanderlene L., Mills, David A., Sundaresan, Vinaik   +13 more
core   +2 more sources

XIAP Deficiency Impairs Colonic Tuft Cell Development and Predisposes to Crohn's Disease

MedComm, Volume 7, Issue 5, May 2026.
XIAP deficiency leads to impaired colonic tuft cells development and JAK–‐STAT pathway hyperactivation in CD patients and mice. Mechanically, XIAP regulates tuft cells development through Wnt–‐TLE4/TCF–‐ASCL2 signaling. Tuft cells deficiency predisposes XIAP‑‐deficient CD patients or Xiap−/−‐/‐ mice to hazardous microbial effects, driving colonic ...
Rongli Fang, Wei Wang, Li Zhang, Jiwei Huang, Lei Huang, Huibo Wu, Yuyin Qi, Lili Li, Liren Tan, Min Zhang, Jianheng Zhu, Xiang Peng, Kanghua Zhong, Ming Zou, Xi Yang, Qiuhua Wang, Changjun Nie, Chaorui Tang, Ning Tang, Lanlan Geng, Hanhan Chen, James E. Vince, Hirokazu Kanegane, Xiaodong Zhao, Huifang Xian, Wenhao Zhou, Min Zhi, Yuxia Zhang, Zhanghua Chen   +28 more
wiley   +1 more source

Morphological and Transcriptomic Analysis of a Beetle Chemosensory System Reveals a Gnathal Olfactory Center [PDF]

, 2016
OR gene tissue expression and their chromosomal localization. a Venn diagram showing the number of ORs expressed (RPKM ≥ 0.5) in the different body parts: antennae, legs, mouthparts (as piece of the head capsule anterior of the antennae), heads (the ...
Alice Montino, Carolin Knoll, Ernst A. Wimmer, Georg Oberhofer, Joachim Schachtner, Karl-Heinz Rexer, Martin Kollmann, Milosz Krala, Robert Kumpf, Sergius Frank, Stefan Dippel   +10 more
core   +10 more sources

Transition From Land to Sea: Comparative Genomics Illuminates the Adaptive Evolution of the Intertidal Spider

Molecular Ecology Resources, Volume 26, Issue 4, May 2026.
ABSTRACT Spiders are renowned for their ecological versatility and silk‐based innovations in materials science, yet marine environments remain virtually uncolonized by this predominantly terrestrial lineage. A striking exception is the obligate intertidal spider genus Desis, whose members have evolved extraordinary physiological and behavioural ...
Fan Li, Yunyun Lv, Chao Bian, Quentin Moana Perrin, Yubo Zhang, Yixiao Wang, Lei Cao, Long Yu, Shengtao Guo, Wei Zhang, Qiong Shi, Daiqin Li   +11 more
wiley   +1 more source

From Development to Aging: Dynamic Roles of the Thymic Medulla in T Cell Biology

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT The thymic medulla is essential for establishing central tolerance, orchestrating the development of a diverse yet self‐tolerant T cell repertoire, and preventing autoimmunity. This process is primarily mediated through interactions between developing thymocytes and antigen‐presenting cells, including thymic epithelial cells (TECs) and ...
Christina Michalaki, Minahil Sharjeel, Jennifer E. Cowan   +2 more
wiley   +1 more source