Results 31 to 40 of about 86,023 (301)

Melanoma cells break down LPA to establish local gradients that drive chemotactic dispersal. [PDF]

open access: yes, 2014
The high mortality of melanoma is caused by rapid spread of cancer cells, which occurs unusually early in tumour evolution. Unlike most solid tumours, thickness rather than cytological markers or differentiation is the best guide to metastatic potential.
Gabriela Kalna (192504)   +76 more
core   +1 more source

An improved chamber for direct visualisation of chemotaxis [PDF]

open access: yes, 2010
There has been a growing appreciation over the last decade that chemotaxis plays an important role in cancer migration, invasion and metastasis. Research into the field of cancer cell chemotaxis is still in its infancy and traditional investigative tools
Andrew J. Muinonen-Martin   +11 more
core   +1 more source

Synergistic effect of CNTF and GDNF on directed neurite growth in chick embryo dorsal root ganglia.

open access: yesPLoS ONE, 2020
It is often critical to improve the limited regenerative capacity of the peripheral nerves and direct neural growth towards specific targets, such as surgically implanted bioengineered constructs.
Vladimir Mashanov   +7 more
doaj   +1 more source

A Chemotactic Factor for Mononuclear Leukocytes

open access: yesExperimental Biology and Medicine, 1971
SummaryChemotactic activity for mononuclear leukocytes was produced when highly purified guinea pig C5 was cleaved by trypsin or by the earlier acting complement components. This chemotactic activity was mediated by C5a, a fragmentation product of the fifth component of complement.
R, Snyderman, H S, Shin, M H, Hausman
openaire   +2 more sources

A novel chemotactic factor derived from the extracellular matrix protein decorin recruits mesenchymal stromal cells in vitro and in vivo.

open access: yesPLoS ONE, 2020
Soft tissue is composed of cells surrounded by an extracellular matrix that is made up of a diverse array of intricately organized proteins. These distinct components work in concert to maintain homeostasis and respond to tissue damage.
Sandi Grainne Dempsey   +5 more
doaj   +1 more source

HiSAT: A Novel Method for the Rapid Diagnosis of Allergy

open access: yesBio-Protocol, 2022
To identify causative substances for allergies to drugs or foods, the lymphocyte transformation test (LTT) is currently widely used as in vitro test, but its accuracy is not satisfactory.
Hirotomo Shibaguchi , Yuki Yasutaka
doaj   +1 more source

Host transcriptional responses following ex vivo re-challenge with Mycobacterium tuberculosis vary with disease status. [PDF]

open access: yesPLoS ONE, 2017
The identification of immune correlates that are predictive of disease outcome for tuberculosis remains an ongoing challenge. To address this issue, we evaluated gene expression profiles from peripheral blood mononuclear cells following ex vivo challenge
Elaine A Yu   +6 more
doaj   +1 more source

Damaged male germ cells induce epididymitis in mice

open access: yesAsian Journal of Andrology, 2020
Epididymitis can be caused by infectious and noninfectious etiological factors. While microbial infections are responsible for infectious epididymitis, the etiological factors contributing to noninfectious epididymitis remain to be defined.
Wei-Hua Liu   +10 more
doaj   +1 more source

Contribution of corneal neovascularization to dendritic cell migration into the central area during human corneal infection. [PDF]

open access: yesPLoS ONE, 2014
Compared with the peripheral corneal limbus, the human central cornea lacks blood vessels, which is responsible for its immunologically privileged status and high transparency.
Mari Narumi   +5 more
doaj   +1 more source

Calcium mimics the chemotactic effect of conditioned media and is an effective inducer of bone regeneration.

open access: yesPLoS ONE, 2019
BackgroundAfter bone resorption, ions and degraded organic components are co-released into the extracellular space. Ions and growth factors, although different in their biological nature, induce a common and coordinated chemotactic effect.
Rubén Aquino-Martínez   +2 more
doaj   +1 more source

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