Results 61 to 70 of about 86,023 (301)

Towards Chemotactic Supramolecular Nanoparticles: From Autonomous Surface Motion Following Specific Chemical Gradients to Multivalency-Controlled Disassembly

, 2021
Nature designs chemotactic supramolecular structures that can selectively bind specific groups present on surfaces, autonomously scan them moving along density gradients, and react once a critical concentration is encountered.
Giovanni M., Pavan, Chiara, Lionello, Andrea, Gardin, Davide, Bochicchio, Ann, Fernandez, S, Thayumanavan, Annalisa, Cardellini, Manisha, Shivrayan   +7 more
core   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Lung fibroblasts produce chemotactic factors for bronchial epithelial cells

, 1989
The interaction between the epithelial cells and the subjacent mesenchymal cells in the airway is thought to play a major role during tissue repair and morphogenesis.
S. I. Rennard, K. A. Rickard, R. F. Ertl, S. Shoji, J. Linder   +4 more
core   +1 more source

Human neutrophils exhibit disparate chemotactic factor gene expression [PDF]

, 1990
The evolution of acute inflammation from initiation through resolution is associated with the changing character of the infiltrating leukocytes. Recruitment of these leukocytes is dependent upon the generation of chemotactic factors that have either ...
Kunkel, Steven L., K. Kasahara, Strieter, Robert M., Allen, R., Standiford, Theodore J., R.M. Strieter, R. Allen, S.L. Kunkel, T.J. Standiford, H.J. Showell, Kasahara, K., Showell, H. J.   +11 more
core   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Effect of chemotactic factors on calcium levels of rabbit neutrophils

, 1979
Studies were undertaken to provide a systematic investigation of the effect of the chemotactic factor, formyl-methionyl-leucyl-phenylalanine (F-Met-Leu-Phe), on the levels of total and exchangeable calcium in rabbit neutrophils.
P. H. Naccache, R. I. Sha'afi, R. J. Petroski, E. L. Becker   +3 more
core   +1 more source

Heterogeneous chemotactic response of eosinophils in patients with bronchial asthma: Its association with disease severity

Allergology International, 1997
We examined the chemotactic response of eosinophils to five eosinophil chemotactic factors (ECF; ECF-PI5, −PI6, −PI7, −PI8 and -PI9) from an established T cell line (ST02) in 31 patients with bronchial asthma (BA).
Takayuki Ohnishi, Hiroki Okada, Misato Terai, Jiro Takahara, Mitsuomi Hiroshima   +4 more
doaj   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

FK506 inhibits human lymphocyte migration and the production of lymphocyte chemotactic factors in liver allograft recipients

, 1996
The macroglide immunosuppressant FK506 is effective at preventing and reversing hepatic allograft rejection. The establishment of graft rejection is dependent upon an influx of lymphocytes from the circulation into the graft in response to locally ...
Adams, David, Liu, Q
core   +1 more source

Chemotactic factor produced by Candida albicans [PDF]

Infection and Immunity, 1977
Candida albicans was found to produce a substance that was chemotactically active for guinea pig polymorphonuclear neutrophils. The chemotactic factor was detected in culture filtrates of organisms grown under aeration and incubated at 37 degrees C for at least 12 h.
openaire   +2 more sources