Results 121 to 130 of about 69,950 (300)

The Endothelial CXCR Family in Vascular Health and Disease

iNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu, Yandi Wu, Suowen Xu, Yu Huang, Li Wang   +4 more
wiley   +1 more source

Leukocyte chemotaxis assay development and studies of leukocyte chemotaxis modulation by metallothionein

, 2006
In this work, we have first developed a novel method, ECIS/taxis, for monitoring cell movement in response to chemotactic factors. In ECIS/taxis, cells migrate under-agarose, and their positions are monitored using the electric cell substrate impedance ...
Hadjout, Nacima
core  

Analysis of the Recovery of Immune Status in the Patients With Paroxysmal Nocturnal Hemoglobinuria After Treatment With C5 Complement Inhibitor

Journal of Clinical Laboratory Analysis, EarlyView.
We retrospectively evaluated the impact of C5 complement inhibition on immune cell profiles and recovery in 27 PNH patients; both CD4+ and CD8+ T cells exhibited partial recovery, while B cell counts increased but remained below normal levels. In contrast, Treg cells were significantly reduced in PNH patients and showed no notable change post‐treatment.
Hui Liu, Mengting Che, Liyan Li, Honglei Wang, Chaomeng Wang, Junshu Wu, Yingying Chen, Zhaoyun Liu, Lijuan Li, Rong Fu   +9 more
wiley   +1 more source

Chemotaxis by polymorphonuclear leukocytes [PDF]

The Journal of cell biology, 1978
openaire   +2 more sources

Differential involvement of RelB in morphine-induced modulation of chemotaxis NO and cytokine production in murine macrophages and lymphocytes

, 2006
Acute morphine impairs innate and acquired immunity. The mechanisms involved in immunosuppression have not been well defined yet. The transcription factor NF-kappaB is a central regulator of immunity, and of the NF-kappaB family, RelB is particularly ...
Alberto E Panerai, D. Lattuada, Donatella Lattuada, Cataldo Martucci, C. Martucci, P.G. Sacerdote, Paola Sacerdote, S. Franchi, A.E. Panerai, Silvia Franchi   +9 more
core   +1 more source

Reconceptualizing Aplastic Anemia—Seed, Worm, Soil

Journal of Clinical Laboratory Analysis, EarlyView.
Aplastic anemia (AA) encompasses a group of hematological syndromes often misdiagnosed, resulting in a decrease in the overall blood cell count and representing a form of bone marrow failure. We reinterpret AA based on the “seed, worm, and soil” doctrine.
Xintong Xu, Zining Wang, Jiaming Hu, Chunyan Liu, Rong Fu   +4 more
wiley   +1 more source

Cyclophilin A cooperates with MIP-2 to augment neutrophil migration

Journal of Inflammation Research, 2011
Shannon J Heine1, Denise Olive1, Ji-Liang Gao2, Philip M Murphy2, Michael I Bukrinsky1, Stephanie L Constant11Department of Microbiology, Immunology and Tropical Medicine, The George Washington University, Washington, DC, USA; 2Laboratory of Molecular ...
Heine SJ, Olive D, Gao JL, Murphy PM, Bukrinsky MI, Constant SL   +5 more
doaj  

DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants

, 2013
The tight regulation of granulocyte chemotaxis is crucial for initiation and resolution of inflammation. Here, we show that DAPK2, a Ca(2+)/CaM-sensitive serine/threonine kinase known to modulate cell death in various cell types, is a novel regulator of ...
Simon, Hans-Uwe, Charaf Benarafa, Saša Rožman, Hans-Uwe Simon, Barbara Geering, Benarafa, Charaf, Stoeckle, Christina, Christina Stoeckle, Oberson, Kevin, Geering, Barbara, Rozman, Sasa, Kevin Oberson   +11 more
core   +1 more source

Surveying immune and inflammatory alterations in periodontitis among individuals with Down syndrome: A preliminary cross‐sectional study

Journal of Periodontology, EarlyView.
Abstract Background Individuals with Down syndrome (DS) are particularly vulnerable to early‐onset and rapidly progressing periodontitis, yet the local immune‐inflammatory alterations that contribute to this susceptibility are not fully understood. This study aimed to characterize cytokine profiles in gingival crevicular fluid (GCF) from individuals ...
Leticia Helena Theodoro, João Victor Soares Rodrigues, Marta A. A. Nuernberg, Pedro Henrique Petrilli, Mabelle de Freitas Monteiro, Valdir Gouveia Garcia, Rafael Scaf de Molon, Renato Correa Viana Casarin   +7 more
wiley   +1 more source

Potential Compounds as Inhibitors of Staphylococcal Virulence Factors Involved in the Development of Thrombosis

Toxins
For many years, staphylococci have been detected mainly in infections of the skin and soft tissues, organs, bone inflammations, and generalized infections.
Anna Lichota, Krzysztof Gwozdzinski, Monika Sienkiewicz   +2 more
doaj   +1 more source