Results 81 to 90 of about 69,950 (300)

Inhibition of leukocyte chemotaxis by immunosuppressive agents. Specific inhibition of lymphocyte chemotaxis by cyclosporine

, 1990
Since chemotaxis is an important mechanism by which leukocytes are recruited to allografts during rejection, the effect of immunosuppressant agents on in vitro chemotactic responses of neutrophils, monocytes, and lymphocytes was studied.
Adams, D H, Neuberger, J M, Elias, E, Wang, L F   +3 more
core  

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

EFFECT OF CERULOPLASMIN THE QUANTITATIVE COMPOSITION AND FUNCTIONAL ACTIVITY OF LEUKOCYTES IN ACUTE PHYSICAL LOAD SUBMAXIMAL POWER

Acta Biomedica Scientifica, 2012
In experiments on animals have shown that the use of ceruloplasmin in acute submaximal exercise capacity leads to an increase in neutrophilic leukocytes pool with a change in their functional activity.
E. N. Ermolayeva, L. V. Krivokhizhina, E. F. Surina-Marysheva   +2 more
doaj  

Circulating Cytokines and Nitric Oxide are Involved in the Inhibition of Neutrophil Migration in Patients with Uterine Cervical Neoplasia

Clinical Medicine Insights: Oncology, 2012
Aim To verify if patients with cervical neoplasia produce mediators that reduce leukocyte function. Methods Control neutrophils incubated with normal serum or serum from pre-invasive or invasive neoplasia patients were assayed for chemotaxis.
Douglas Côbo Micheli, Paulo Cesar Fernandes, João Celso Garcia Cruvinel, Isabela Destro Nomelini, Eddie Fernando Candido Murta, Beatriz Martins Tavares-Murta   +5 more
doaj   +1 more source

A STUDY POLYMORPHONUCLER LEUKOCYTE CHEMOTAXIS REPORT 1: EFFECT OF ANTIBIOTICS ON CHEMOTAXIS OF HUMAN POLYMORPHONUCLEAR LEUKOCYTES

, 1979
The effect of five different antibiotics on chemotaxis of human polymorphonuclear (PMN) leukocytes was studied in an in vitro system using an agarose plate method.
中尾, 実信, 石神, 襄次, 守殿, 貞夫, 黒田, 泰二   +3 more
core  

Engineered Carbon Dots from a Traditional Herb Pair Orchestrate Concurrent Antioxidant and AP‐1‐Mediated Inflammation to Attenuate Renal Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study integrates two complementary traditional Chinese medicine components as precursors to synthesize bioactive AM‐AS@CDs. Compared with single‐component CDs, these dual‐component CDs exhibit enhanced antioxidant capacity and superior renoprotective effects.
Bixiao Liu, Fuying Zhu, Zhuqing Wang, Jiawen Chen, Xiaomiao Cui, Congzhong Yang, Yao Peng, Dengyuan Feng, Li Lu, Hui Wei, Xiaozhi Zhao   +10 more
wiley   +1 more source

Misoprostol Inhibits Equine Neutrophil Adhesion, Migration, and Respiratory Burst in an In Vitro Model of Inflammation

Frontiers in Veterinary Science, 2017
In many equine inflammatory disease states, neutrophil activities, such as adhesion, migration, and reactive oxygen species (ROS) production become dysregulated.
Emily Medlin Martin, Rebecca Louise Till, Mary Katherine Sheats, Mary Katherine Sheats, Samuel L. Jones, Samuel L. Jones   +5 more
doaj   +1 more source

Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]

, 1999
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Erl, Wolfgang, Weber, Christian, Kim S. C. Weber, Weber, Kim S.C., Weber, Peter C., Wolfgang Erl, Peter C. Weber, Christian Weber   +7 more
core   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

Leukotriene B₄-loaded microspheres: a new therapeutic strategy to modulate cell activation

BMC Immunology, 2008
Background Leukotriene B4 (LTB4) is a potent inflammatory mediator that also stimulates the immune response. In addition, it promotes polymorphonuclear leukocyte phagocytosis, chemotaxis, chemokinesis and modulates cytokines release.
Sanz Maria J, Soares Edson G, Jose Peter J, Sorgi Carlos A, Rius Cristina, Piqueras Laura, Nicolete Roberto, Faccioli Lúcia H   +7 more
doaj   +1 more source