Results 1 to 10 of about 2,482,303 (417)

Enhancement of chemotherapy using oncolytic virotherapy: Mathematical and optimal control analysis [PDF]

Math. Biosci. Eng. 15 (2018), no. 6, 1435--1463, 2018
Oncolytic virotherapy (OV) has been emerging as a promising novel cancer treatment that may be further combined with the existing therapeutic modalities to enhance their effects. To investigate how OV could enhance chemotherapy, we propose an ODE based model describing the interactions between tumour cells, the immune response, and a treatment ...
Eladdadi, Amina, Malinzi, Joseph, Ouifki, Rachid, Torres, Delfim F. M., White, K. A. Jane   +4 more
arxiv   +3 more sources

Robust Individual Circadian Parameter Estimation for Biosignal-based Personalisation of Cancer Chronotherapy [PDF]

arXiv, 2016
In cancer treatment, chemotherapy is administered according a constant schedule. The chronotherapy approach, considering chronobiological drug delivery, adapts the chemotherapy profile to the circadian rhythms of the human organism. This reduces toxicity effects and at the same time enhances efficiency of chemotherapy.
Arbaud, Alexandre, Lévi, Francis, Mikut, Ralf, Reischl, Markus, Schott, Benjamin, Stegmaier, Johannes   +5 more
arxiv   +2 more sources

In vitro activity of biapenem and other carbapenems against Russian clinical isolates of Pseudomonas aeruginosa, Acinetobacter spp., and Enterobacterales [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2021
Objective. To evaluate in vitro activity of biapenem and other clinically available carbapenems against Russian clinical isolates of Enterobacterales, Pseudomonas aeruginosa и Acinetobacter spp., including isolates with acquired fermentative mechanisms ...
Kozlov R.S., Azyzov I.S., Dekhnich A.V., Ivanchik N.V., Kuzmenkov A.Yu., Martinovich А.А., Mikotina A.V., Sukhorukova M.V., Trushin I.V., Edelstein M.V.   +9 more
doaj   +1 more source

AMRmap – antibiotic resistance surveillance system in Russia [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2021
Objective. To review the basic principles and functionality of the AMRmap online resource. Materials and Methods. The AMRmap platform was developed using the R programming language and various downloadable modules – packages.
Kuzmenkov A.Yu., Vinogradova A.G., Trushin I.V., Edelstein M.V., Avramenko A.A., Dekhnich A.V., Kozlov R.S.   +6 more
doaj   +1 more source

In vitro activity of cefpodoxime against Russian clinical isolates of Haemophilus influenzae, Streptococcus pneumoniae and Streptococcus pyogenes [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2023
Objective. To determine in vitro activity of oral III generation cephalosporin cefpodoxime against clinical isolates of Haemophilus influenzae, Streptococcus pneumoniae and Streptococcus pyogenes isolated from patients with community-acquired ...
Kozlov R.S., Ivanchik N.V., Skleenova E.Yu., Mikotina A.V., Azyzov I.S., Trushin I.V., Dekhnich A.V.   +6 more
doaj   +1 more source

In vitro activity of thiamphenicol against Haemophilus influenzae, Streptococcus pneumoniae and Streptococcus pyogenes clinical isolates [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2021
Objective. To determine in vitro activity of thiamphenicol and other clinically available antimicrobials against clinical isolates of Haemophilus influenzae, Streptococcus pneumoniae and Streptococcus pyogenes. Materials and Methods.
Ivanchik N.V., Sukhorukova M.V., Chagaryan A.N., Trushin I.V., Dekhnich A.V., Kozlov R.S.   +5 more
doaj   +1 more source

Practice of local antibiotic resistance monitoring at hospitals in various regions of the Russian Federation [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2022
Objective. To analyze the features of local antibiotic resistance monitoring at hospitals in the Russian Federation. Materials and Methods. The study involved a survey of 305 institutions.
Kuzmenkov A.Yu., Vinogradova A.G., Trushin I.V., Kozlov R.S.   +3 more
doaj   +1 more source

Neoadjuvant Nivolumab plus Chemotherapy in Resectable Lung Cancer.

New England Journal of Medicine, 2022
BACKGROUND Neoadjuvant or adjuvant chemotherapy confers a modest benefit over surgery alone for resectable non-small-cell lung cancer (NSCLC). In early-phase trials, nivolumab-based neoadjuvant regimens have shown promising clinical activity; however ...
P. Forde, J. Spicer, Shun Lu, M. Provencio, T. Mitsudomi, M. Awad, E. Felip, S. Broderick, J. Brahmer, S. Swanson, K. Kerr, Changli Wang, T. Ciuleanu, G. Saylors, F. Tanaka, H. Ito, Keke Chen, M. Liberman, E. Vokes, J. Taube, C. Dorange, Junliang Cai, J. Fiore, A. Jarkowski, D. Balli, M. Sausen, D. Pandya, C. Calvet, N. Girard   +28 more
semanticscholar   +1 more source

AMRexpert – online platform for interpretation, verification and validation of antimicrobial susceptibility testing [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2023
Objective. To review the key principles and functionality of AMRexpert online platform. Materials and Methods. The information part of the platform is comprised of rules based on the EUCAST recommendations and various standards for interpreting the ...
Vinogradova A.G., Kuzmenkov A.Yu., Trushin I.V., Edelstein M.V., Sukhorukova M.V., Starostenkov A.A.   +5 more
doaj   +1 more source

AMRcloud: a new paradigm in monitoring of antibiotic resistance [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2019
Antimicrobial resistance is a growing threat to global public health and requires closer attention from the medical community. Antibiotic resistance monitoring systems play a key role in observing the antimicrobial susceptibility changes for rational ...
Kuzmenkov A.Yu., Vinogradova A.G., Trushin I.V., Avramenko A.A., Edelstein M.V., Dekhnich A.V., Kozlov R.S.   +6 more
doaj   +1 more source