ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
MOGA-Based Multi-drug Optimisation for Cancer Chemotherapy [PDF]
This paper presents a novel method of multi-drug scheduling using multi-objective genetic algorithm (MOGA) that can find suitable/optimum dosages by trading-off between cell killing and toxic side-effects of chemotherapy treatment.
Majumder, Azim +9 more
core +1 more source
Antimicrobial resistance of nosocomial Acinetobacter spp. isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014 [PDF]
Acinetobacter baumannii and related species of the A. baumannii complex are the common and one of the most difficult-to-treat nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 568 isolates of Acinetobacter spp ...
Sukhorukova M.V. +7 more
doaj
Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan +18 more
wiley +1 more source
Chemotherapy effects on brain glucose metabolism at rest [PDF]
Background: A growing number of studies reports that chemotherapy may impair brain functions inducing cognitive changes which can persist in a subset of cancer survivors.
Riccardo Torta +14 more
core
Glioblastoma (GBM) remains one of the most aggressive and challenging brain tumors. Unfortunately, current clinical treatment options offer limited efficacy, highlighting the necessity for uncovering novel therapeutic strategies.
Tianyi Huang +3 more
doaj +1 more source
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Antimicrobial Resistance of Gram-negative Microorganisms Causing Complicated Intra-abdominal Infections in Russia [PDF]
Objective. To assess antimicrobial resistance of gram-negative microorganisms causing complicated intra-abdominal infections (IAI) in Russia. Materials and Methods.
Kozlov R.S. +4 more
doaj
Use of in vitro human keratinocyte models to study the effect of cooling on chemotherapy drug-induced cytotoxicity [PDF]
A highly distressing side-effect of cancer chemotherapy is chemotherapy-induced alopecia (CIA). Scalp cooling remains the only treatment for CIA, yet there is no experimental evidence to support the cytoprotective capacity of cooling. We have established
van den Hurk, Corina J. +6 more
core +1 more source
Development of criteria for interpretation and quality assessment of the results of susceptibility testing of Enterobacterales and Pseudomonas aeruginosa to cefepime-sulbactam [PDF]
Objective. To develop criteria for the interpretation and quality assurance of the results of susceptibility testing of Enterobacterales and P. aeruginosa to cefepime-sulbactam. Materials and Methods. The study included 1035 clinical Enterobacterales
Edelstein M.V. +2 more
doaj +1 more source

