Antimicrobial Resistance of Gram-negative Microorganisms Causing Complicated Intra-abdominal Infections in Russia [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2015 Objective. To assess antimicrobial resistance of gram-negative microorganisms causing complicated intra-abdominal infections (IAI) in Russia. Materials and Methods.
Kozlov R.S. +4 more
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Antimicrobial resistance of nosocomial Staphylococcus aureus isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014 [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2017 The study included 418 of the 841 clinical isolates of S. aureus, which were regarded as nosocomial. These 418 clinical nosocomial S. aureus strains were isolated in 2013-2014 from patients hospitalized in 25 hospitals in 19 Russian cities.
Romanov A.V. +7 more
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Development of criteria for interpretation and quality assessment of the results of susceptibility testing of Enterobacterales and Pseudomonas aeruginosa to cefepime-sulbactam [PDF]
Клиническая микробиология и антимикробная химиотерапияObjective. To develop criteria for the interpretation and quality assurance of the results of susceptibility testing of Enterobacterales and P. aeruginosa to cefepime-sulbactam. Materials and Methods. The study included 1035 clinical Enterobacterales
Edelstein M.V. +2 more
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Frontiers in Pharmacology, 2023 Background: Although oxidative stress is known to contribute to cancer, and endogenous and exogenous antioxidants are thought to prevent tumorigenesis by suppressing oxidative stress-induced DNA damage, antioxidants have also been reported to show ...
Jiahao Zhu +9 more
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Scientific Reports, 2017 ROS1 rearrangement is observed in 1–2% of non-small cell lung cancers (NSCLC). The ROS1 tyrosine kinase inhibitor (TKI) crizotinib has induced marked tumour shrinkage in ROS1-rearranged cancers.
Hayato Ogura +5 more
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Clinical resistance to platinum chemotherapy in ovarian cancer [PDF]
, 2009 Platinum drugs are the most active agents in ovarian cancer. Their cytotoxicty results from DNA crosslinking. High tumour response rates are seen, but 80 % of patients relapse. Major mechanisms of platinum resistance in patients remain to be established.
Newton, C., Newton, C
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Scientific Reports, 2022 The unfolded protein response (UPR) is an adaptive stress response pathway that is essential for cancer cell survival under endoplasmic reticulum stress such as during glucose starvation.
Kazuhiro Kunimasa +8 more
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Ceftaroline fosamil – fifth-generation cephalosporin with anti-MRSA activity in the treatment of severe infections in pediatric practice [PDF]
Клиническая микробиология и антимикробная химиотерапияСeftaroline fosamil is a fifth-generation cephalosporin and a unique β-lactam and the only currently registered in the Russian Federation cephalosporin with activity against MRSA. Сeftaroline is approved for use in pediatric practice for the treatment of
Andreeva I.V. +2 more
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Cisplatin-Based Chemotherapy for Pulmonary Metastasized Germ Cell Tumors of the Testis - Be Aware of Acute Respiratory Distress Syndrome [PDF]
, 2009 Background: Cisplatin-based combination chemotherapy is regarded as standard of care for patients with advanced germ cell tumors. In patients with lung metastases and a high tumor load, an association between induction chemotherapy and the development of
Parhofer, Klaus G. +6 more
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Long-term therapeutic response in gallbladder cancer — the potential of chemoimmunotherapy
Oncology in Clinical PracticeMalignant biliary tract tumors, including gallbladder cancer and cholangiocarcinoma, are associated with particularly poor prognoses. For many years, chemotherapy with cisplatin and gemcitabine was the only available treatment option for patients with ...
Marta Pabianek +3 more
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