Results 81 to 90 of about 1,535,241 (215)
npj Precision OncologyKRAS-specific inhibitors have shown promising antitumor effects, especially in non-small cell lung cancer, but limited efficacy in colorectal cancer (CRC) patients.
Kohei Maruyama +7 more
doaj +1 more source
Kaohsiung Journal of Medical Sciences, 2013 Preoperative elevation of serum C-reactive protein (CRP) is reportedly associated with poor prognosis in several types of cancer. This study investigated the role of serum CRP as a prognostic factor in early-stage esophageal squamous cell carcinoma (ESCC)
Zheng-Bo Song +6 more
doaj +1 more source
Antibiotic dosing in obesity: size does matter? [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2017 Currently, from 15 to 50% of the population in the developed countries has obesity. Overall, patients with obesity have a higher risk of infection; they are more likely to develop infectious complications after surgical interventions and have a higher ...
Andreeva I.V. +2 more
doaj
Podoplanin enhances lung cancer cell growth in vivo by inducing platelet aggregation
Scientific Reports, 2017 Podoplanin/Aggrus, known as a platelet aggregation-inducing factor, is frequently overexpressed in lung squamous cell carcinomas (LSCC) and glioblastomas among other tumours, and its expression has been reported to be correlated with poor prognosis ...
Kenichi Miyata +4 more
doaj +1 more source
, 2020 Background Chemotherapy-related coronary artery disease (CAD) is becoming an emerging issue in clinic. However, the underlying mechanism of chemotherapy-related CAD remains unclear. Objective The study investigated the association between chemotherapy
Qian Yang (300330) +9 more
core +1 more source
Clinical relevance of soluble c-erbB-2 for patients with metastatic breast cancer predicting the response to second-line hormone or chemotherapy [PDF]
, 2002 Concentrations of soluble c-erbB-2 were determined in the sera of 64 patients with distant metastasis from advanced breast cancer receiving second-line hormone or chemotherapy in comparison to 35 breast cancer patients without detectable recurrent ...
Classen, S. +5 more
core +1 more source
A new concurrent chemotherapy with vinorelbine and mitomycin C in combination with radiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck [PDF]
, 2005 Objective: The purpose of this pilot study was to evaluate the feasibility and toxicity of concurrent chemotherapy with vinorelbine and mitomycin C in combination with accelerated radiotherapy (RT) in patients with locally advanced cancer of the head and
Wilkowski, R. +5 more
core +1 more source
A macrocyclic kinase inhibitor overcomes triple resistant mutations in EGFR-positive lung cancer
npj Precision OncologyBrigatinib-based therapy was effective against osimertinib-resistant EGFR C797S mutants and is undergoing clinical studies. However, tumor relapse suggests additional resistance mutations might emerge.
Mai Suzuki +15 more
doaj +1 more source
Thoracic Cancer, 2020 Background Anaplastic lymphoma kinase (ALK) fusion genes are found in 3%–5% of non‐small cell lung cancers (NSCLCs). ALK inhibitors show a very high response rate to ALK‐positive NSCLCs. However, the emergence of acquired resistance is inevitable.
Ken Takahashi +11 more
doaj +1 more source
, 2011 To evaluate the efficacy of intravenous ramosetron plus dexamethasone for the prevention of acute chemotherapy- induced nausea and vomiting. Cancer patients scheduled to receive chemotherapy containing either of the four drugs ( cisplatin, doxorubicin ...
何景良;蘇五洲;謝瑞坤;林宗哲;趙祖怡 +1 more
core +1 more source