ABSTRACT Aim To examine the significance of portal vein tumor thrombus (PVTT) as a prognostic factor for patients with pancreatic ductal adenocarcinoma (PDAC) treated with chemoradiotherapy (CRT) followed by surgery. Methods The study retrospectively examined 313 patients with borderline resectable (BR) or locally advanced (LA) PDAC who underwent CRT ...
Aoi Hayasaki +9 more
wiley +1 more source
Socioeconomic- and Insurance-Based Inequities in Oncotype DX Testing and Score-Guided Treatment. [PDF]
Williams CP +6 more
europepmc +1 more source
Abstract Pharyngeal high‐resolution manometry with impedance (P‐HRM‐I) is an established assessment method used to evaluate pharyngeal swallowing. It provides precise quantification of swallowing biomechanics that enable the detection of alterations in swallowing physiology.
Mistyka Schar +5 more
wiley +1 more source
Pathological complete response and survival after neoadjuvant chemotherapy in patients with stage I TNBC: a registry-based study. [PDF]
de Graaf M +5 more
europepmc +1 more source
This study introduces a framework that combines graph neural networks with causal inference to forecast recurrence and uncover the clinical and pathological factors driving it. It further provides interpretability, validates risk factors via counterfactual and interventional analyses, and offers evidence‐based insights for treatment planning ...
Jubair Ahmed +3 more
wiley +1 more source
Survival benefit of adjuvant chemotherapy for duodenal adenocarcinoma: a retrospective cohort study and propensity score-matched analysis. [PDF]
Luo Y +6 more
europepmc +1 more source
New approaches to treating chronic obstructive pulmonary disease with Colla corii asini
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang +5 more
wiley +1 more source
Efficacy and safety of oral 5-FU-based adjuvant chemotherapy for geriatric patients with colorectal cancer: Integrated analysis of seven clinical trials conducted at the Japanese Foundation for Multidisciplinary Treatment of Cancer. [PDF]
Hoshino N +13 more
europepmc +1 more source
Tumor growth inhibition does not predict survival benefit in a clinically relevant metastasis model. Tumor local growth and systemic metastasis represent distinct biological processes. In the 4T1‐OtR model, although chemotherapy significantly suppresses primary tumor growth, it fails to prevent distant metastasis or extend overall survival.
Lingli Luo +6 more
wiley +1 more source
Baseline Tumor Biology Predicts Survival After Recurrence in Gastric Cancer: Impact of LVI, PNI, and HER2 Status. [PDF]
Ağdaş G, Demir MS.
europepmc +1 more source

