Results 231 to 240 of about 747,376 (295)

Crosstalk Between Parkinson's Disease and Colorectal Cancer: Genetic Mechanisms, Gut Microbiota, and Therapeutic Insights

open access: yesHealth Care Science, EarlyView.
This review elucidates the crosstalk between Parkinson's disease and colorectal cancer, driven by shared genetics (PRKN, PINK1, DJ‐1) involving oxidative stress, cell cycle regulation, and inflammation. It identifies the gut microbiota—via functional amyloids and short‐chain fatty acids (SCFAs)—as a mechanistic bridge, offering insights for dual ...
Jiacheng Ying   +6 more
wiley   +1 more source

Early versus late closure of protective ileostomy after rectal cancer surgery. [PDF]

open access: yesInt J Colorectal Dis
Khajeh E   +7 more
europepmc   +1 more source

Interpretable Machine Learning Model for Fungal Infection Prediction: A Real‐World Study

open access: yesHealth Care Science, EarlyView.
Our study successfully developed and validated a machine learning model based on large‐scale electronic health record data to predict the risk of fungal infections in hospitalized patients. Through a Streamlit‐powered web platform, the model was seamlessly embedded into clinical workflows, completing the full pipeline from model construction to real ...
Jinru Yang   +5 more
wiley   +1 more source

Predominance of In‐Field Recurrence After Radiotherapy for Sinonasal Cancer: A Single‐Center Retrospective Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Sinonasal malignancies (SNM) are rare, heterogeneous tumors with poor prognosis. There is an unmet need to improve treatment outcomes. Despite advances in imaging and molecular classification, optimal curative radiotherapy (RT) strategies remain undefined.
M. de Ridder   +11 more
wiley   +1 more source

Comparison of In‐Office and General Anesthesia Biopsies for Oropharyngeal Squamous Cell Carcinoma in a Public Healthcare System

open access: yesHead &Neck, EarlyView.
ABSTRACT Background We compared treatment delays, costs, and management impact between oropharyngeal squamous cell carcinoma (OPSCC) patients undergoing in‐office versus general anesthesia panendoscopy‐guided biopsies in two large tertiary centers in a public healthcare system. Methods All OPSCC patients included were treated between 2010 and 2024 with
Samuel Bellavance   +10 more
wiley   +1 more source

What are the Unmet Needs in Managing Digestive Neuroendocrine Carcinomas? [PDF]

open access: yesCurr Oncol Rep
Sorbye H   +6 more
europepmc   +1 more source

Systemic Treatments for Recurrent or Metastatic Sinonasal Carcinomas: A Retrospective Multicenter Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Introduction Sinonasal cancers are rare and heterogeneous and pose a therapeutic challenge at an advanced stage due to the lack of data on appropriate systemic management. Methods This retrospective multicenter study analyzed 83 patients with recurrent or metastatic sinonasal carcinomas ineligible for curative treatment, treated in France ...
Marie Degrange   +16 more
wiley   +1 more source

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