Efficient Synthesis of Cannabinoid Acids
In this study, an alternative synthesis of cannabinoid acids was developed based on an O→C acyl rearrangement. Specifically, this strategy involved regioselective bromination followed by halogen–lithium exchange and intramolecular nucleophilic addition, which led to successful carboxylation.
Ryosuke Arai +8 more
wiley +1 more source
Treatment Outcomes and Toxicity of Cisplatin-Etoposide-Based Regimens and Carboplatin-Paclitaxel as Adjuvant Chemotherapy for Ovarian Adult Granulosa Cell Tumors: A Multicenter Retrospective Cohort Study. [PDF]
Geçgel A +13 more
europepmc +1 more source
ABSTRACT Background Postoperative radiotherapy is the standard treatment for locally advanced oral squamous cell carcinoma (OSCC); however, the indication for neck irradiation (NI) in pN0 patients remains debatable. We evaluated whether the omission of NI compromises outcomes in pT3–T4 pN0 patients treated with adequate neck dissection (ND).
Mathilde Mirallié +9 more
wiley +1 more source
Return to Work After Adjuvant Chemotherapy for Colon Cancer: A Retrospective Study With Exploratory Occupational Analysis. [PDF]
Duarte Branco V +8 more
europepmc +1 more source
A Discharge Summary Prompt Reduces Postoperative Radiotherapy Delay in Head and Neck Cancer Patients
ABSTRACT Background Delays in postoperative radiotherapy (PORT) beyond 6 weeks are associated with worse outcomes in head and neck cancer (HNC). This study evaluated whether a discharge summary prompt could reduce PORT delay. Methods A retrospective review of patients from 2018 to 2023 was used as a pre‐intervention baseline.
Andreja Radevic +10 more
wiley +1 more source
Adjuvant chemotherapy and survival after resection for pulmonary large-cell neuroendocrine carcinoma: a dual-center time-dependent analysis. [PDF]
Liang L +10 more
europepmc +1 more source
ABSTRACT Background Frailty and sarcopenia may influence head and neck cancer (HNC) treatment outcomes, including dysphagia. Current understanding of this relationship, however, remains limited. This scoping review aimed to synthesize existing evidence on the relationship between frailty and/or sarcopenia and dysphagia in adults with HNC.
Rishni Perera +4 more
wiley +1 more source
Beyond local control: what does a pathological complete response tell us about systemic disease in rectal cancer? [PDF]
Lee HG.
europepmc +1 more source
Measurement Tools for Radiation‐Induced Fibrosis in Head and Neck Cancer: A Systematic Review
ABSTRACT Background Radiation‐induced fibrosis is a common, often debilitating late effect of head and neck cancer (HNC) treatment. An updated systematic review is needed to evaluate the reliability, validity, and clinical utility of fibrosis measurement tools.
Vanessa Helou +11 more
wiley +1 more source
Adjuvant FOLFIRINOX versus S-1 monotherapy for resected PDAC: retrospective real-world data. [PDF]
Tang H +6 more
europepmc +1 more source

