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STC1‐Based Activation of NF‐κB Signaling Pathway Induces Epthithelial–Mesenchymal Transition Thus Promotes Progression and Temozolomide Resistance of Glioblastoma

open access: yesThe FASEB Journal, Volume 39, Issue 19, 15 October 2025.
Glioblastoma (GBM), a neuroepithelial‐derived lethal malignancy, remains incurable due to its intrinsic heterogeneity, necessitating molecular biomarkers for precision therapeutics. STC1 promotes GBM progression and temozolomide (TMZ) resistance by activating the NF‐κB signaling pathway, which drives epithelial–mesenchymal transition (EMT) and enhances
Jia Wang   +7 more
wiley   +1 more source

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