Results 41 to 50 of about 38,260 (246)

Why Can't Rodents Vomit? A Comparative Behavioral, Anatomical, and Physiological Study [PDF]

, 2013
The vomiting (emetic) reflex is documented in numerous mammalian species, including primates and carnivores, yet laboratory rats and mice appear to lack this response.
Andrews, PLR, Yates, Bill J., Andrews, PL, Yates, BJ, Allysa Nagy, Charles C Horn, Gathright, GR, Kimball, Bruce A., Wang, H, James Kaus, Horn, Charles C., Bill J. Yates, Charles C. Horn, Kaus, J, Hong Wang, Dienel, S, Bruce A. Kimball, Paul L. R. Andrews, Horn, CC, Dienel, Samuel, Kimball, BA, Nagy, A, Nagy, Allysa, Gordon R Gathright, Gathright, Gordon R., Andrews, Paul L. R., Bruce A Kimball, Kaus, James, Wang, Hong, Samuel Dienel, Paul L R Andrews, Bill J Yates, Gordon R. Gathright   +32 more
core   +1 more source

Chemotherapy-related nausea and vomiting - past reflections, present practice and future management [PDF]

, 2004
Although much progress has occurred in the last decade regarding the management of chemotherapy-induced nausea and vomiting, these remain among the most intolerable side-effects of treatment and patients continue to report the negative impact such ...
M. MILLER, Miller, Morven, Kearney, Nora, N. KEARNEY   +3 more
core   +1 more source

Olanzapine for the Prevention and Treatment of Chemotherapy-Induced Nausea and Vomiting: A Review to Identify the Best Way to Administer the Drug

Current Oncology, 2022
Common treatment methods for malignant tumors include surgery, chemotherapy, radiotherapy, immunotherapy, targeted therapy, etc., among which chemotherapy plays an important role.
Xiao-Ling Zhang, Jie-Er Ying
doaj   +1 more source

Tracking Health Related Quality of Life From Diagnosis to Follow‐Up Among Australian Children With Acute Lymphoblastic Leukaemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukaemia (ALL) is one of the most treatable forms of paediatric cancer; however, there is a substantial burden of treatment‐related toxicities (TRTs). In addition, the long‐term changes in children's health‐related quality of life (HRQoL) due to toxic treatments are not well understood.
Clare Ghows, Clarissa E. Schilstra, Karen McCleary, Nancy E. Briggs, Rishi S. Kotecha, Richard De Abreu Lourenco, Shanti Ramachandran, Ruelleyn Cockcroft, Rachel Conyers, Siobhan Cross, Luciano Dalla‐Pozza, Peter Downie, Tamas Revesz, Michael Osborn, Frank Alvaro, Claire E. Wakefield, Glenn M. Marshall, Toby Trahair, Marion K. Mateos, Joanna E. Fardell   +19 more
wiley   +1 more source

Motion sickness, stress and the endocannabinoid system [PDF]

, 2010
A substantial number of individuals are at risk for the development of motion sickness induced nausea and vomiting (N&V) during road, air or sea travel.
Kreth Simone, Feuerecker, Matthias, Matthias Feuerecker, Ines Kaufmann, Kaufmann, Ines, Kreth, Simone, Thieme, Detlef, Thieme Detlef, Choukèr Alexander, Schelling Gustav, Feuerecker Matthias, Michael Vogeser, Kaufmann Ines, Vogeser Michael, Manfred Thiel, Schelling, Gustav, Vogeser, Michael, Choukèr, Alexander, Detlef Thieme, Thiel, Manfred, Gustav Schelling, Alexander Choukèr, Daniela Hauer, Thiel Manfred, Hauer, Daniela, Simone Kreth, Hauer Daniela   +26 more
core   +1 more source

GIP receptor agonism blocks chemotherapy-induced nausea and vomiting

Molecular Metabolism, 2023
Objective: Nausea and vomiting remain life-threatening obstacles to successful treatment of chronic diseases, despite a cadre of available antiemetic medications.
Tito Borner, Benjamin C. Reiner, Richard C. Crist, C. Daniel Furst, Sarah A. Doebley, Julia G. Halas, Minrong Ai, Ricardo J. Samms, Bart C. De Jonghe, Matthew R. Hayes   +9 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

Advanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen, Jintao Guo, Fei Li, Mingjie Gao, Runyang Li, Zhaozhang Huang, Yaolin Zheng, Chunyi Gao, Jihuan Hou, Qiang Yu, Bowen Zheng, Xuemei Chen, Wenqing Zhang, Xiaoting Hong, Yali Zheng, Daxuan Wang, Qiyuan Li, Tianhui Hu, Yan‐yan Zhan   +18 more
wiley   +1 more source

Impact of Nausea and Vomiting on Quality of Life in Cancer Patients During Chemotherapy

Health and Quality of Life Outcomes, 2003
It is commonly claimed that the nausea and vomiting accompanying cytotoxic chemotherapy have a negative impact on health-related quality of life. While this may seem self-evident, until a few years ago there was little empirical data demonstrating that ...
Roila Fausto, Ballatori Enzo
doaj   +1 more source

Risk factors associated with antineoplastic chemotherapy-induced nausea and vomiting

Revista de Saúde Pública, 2020
OBJECTIVE: To estimate the incidence and to evaluate risk factors for antineoplastic nausea and vomiting with high and moderate emetogenic chemotherapy in adult patients in the first treatment cycle.
Giovana Paula Rezende Simino, Ilka Afonso Reis, Francisco de Assis Acurcio, Eli Iola Gurgel Andrade, Natalia Maria Linhares Brazil, Mariângela Leal Cherchiglia   +5 more
doaj   +2 more sources