Results 51 to 60 of about 35,499 (199)

Efficient Synthesis of Cannabinoid Acids

European Journal of Organic Chemistry, EarlyView.
In this study, an alternative synthesis of cannabinoid acids was developed based on an O→C acyl rearrangement. Specifically, this strategy involved regioselective bromination followed by halogen–lithium exchange and intramolecular nucleophilic addition, which led to successful carboxylation.
Ryosuke Arai, Hikari Nishiguchi, Kayo Nakamura, Hiroko Abe, Akihiko Ishida, Manabu Tokeshi, Kyohei Higashi, Akiyoshi Saitoh, Hideyo Takahashi   +8 more
wiley   +1 more source

Treatment‐Related Adverse Events and Health‐Related Quality of Life Associated With Immune Checkpoint Inhibitor Treatment for Mucosal Head and Neck Squamous Cell Carcinoma: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell, E. C. Ward, L. R. Wishart, R. Perera, C. Barrett, K. A. Edmiston, E. Mitchell, A. Pigott, R. Pitt, K. Russell, B. A. Chan, R. Ladwa   +11 more
wiley   +1 more source

D2 Receptors and Sodium Ion Channel Blockades of the Basolateral Amygdala Attenuate Lithium Chloride-Induced Conditioned Taste Aversion Applying to Cancer Chemotherapy Nausea and Vomiting

Brain Sciences, 2023
Cancer patients regularly suffer from the behavioral symptoms of chemotherapy-induced nausea and vomiting. Particularly, it is involved in Pavlovian conditioning. Lithium chloride (LiCl) was used as the unconditioned stimulus (US) and contingent with the
Zhi-Yue Gao, Chung Ming Huang, Cai-N Cheng, Andrew Chih-Wei Huang   +3 more
doaj   +1 more source

Trismus and Health‐Related Quality of Life in HNC Patients up to 10 Years Post‐Radiotherapy Completion

Head &Neck, EarlyView.
ABSTRACT Background This prospective study investigates trismus prevalence, quality of life (QOL), and trismus‐related symptoms in HNC patients up to 10 years post‐radiotherapy (RT). Methods A total of 211 patients with HNC receiving RT were followed pretreatment, 12, 60, and 120 months post‐RT.
Therese Karlsson, Lisa Tuomi, Caterina Finizia   +2 more
wiley   +1 more source

Applications and prospects of artificial intelligence and digital medicine in pediatric nasal skull base tumors

Pediatric Investigation, EarlyView.
Pediatric nasal skull base tumors present diagnostic and therapeutic challenges due to their deep location, nonspecific symptoms, and the narrow nasal cavity in children. Although artificial intelligence (AI) and digital medicine have advanced early diagnosis, multidisciplinary treatment, and prognosis, their application in these rare tumors remains ...
Xiuping Wu, Jing Wei, Chen Liu, Pengpeng Wang, Wentong Ge, Yang Han   +5 more
wiley   +1 more source

Anticipatory nausea, risk factors, and its impact on chemotherapy-induced nausea and vomiting : results from the pan European Emesis registry study

, 2016
Context Anticipatory (prechemotherapy) nausea (AN) is a classic conditioned symptom not responding well to current antiemetics. Minimal work has been done to assess its risk factors and impact on chemotherapy-induced nausea and vomiting (CINV ...
Molasiotis, A., Burke, T.A., Aapro, M., Molassiotis, Alexander, Lee, Paul H., Gascon, Pere, Molasiotis, A, Gascon, P, Aapro, Matti, Aapro, M, Lee, PH, Roila, F, Roila, F., Gascon, P., Burke, TA, Dicato, M., Dicato, M, Burke, Thomas A., Roila, Fausto, Dicato, Mario, et al., Lee, P.H.   +21 more
core   +1 more source

Chemotherapy-induced nausea and vomiting: A narrative review to inform dietetics practice [PDF]

, 2016
Chemotherapy-induced nausea and vomiting (CINV) are common nutrition-impact symptoms experienced by cancer patients. They exert a detrimental effect on dietary intake, risk of malnutrition and quality of life.
McKavanagh, Dan, Isenring, Liz, Marx, Wolfgang, Kiss, Nicole, McCarthy, Alexandra L.   +4 more
core   +2 more sources

Bortezomib‐based chemotherapy in Chinese pediatric patients with relapsed/refractory acute lymphoblastic leukemia: A single‐center retrospective study

Pediatric Investigation, EarlyView.
Bortezomib‐based chemotherapy achieved an 88.9% remission rate in Chinese pediatric patients with relapsed/refractory B‐cell acute lymphoblastic leukemia, enabling 62.5% of responders to bridge to transplantation, while T‐cell acute lymphoblastic leukemia showed no response.
Xingyu Zhao, Jian Wang, Liping Que, Dunhua Zhou, Jianpei Fang, Luhong Xu   +5 more
wiley   +1 more source

Motion sickness, stress and the endocannabinoid system [PDF]

, 2010
A substantial number of individuals are at risk for the development of motion sickness induced nausea and vomiting (N&V) during road, air or sea travel.
Kreth Simone, Feuerecker, Matthias, Matthias Feuerecker, Ines Kaufmann, Kaufmann, Ines, Kreth, Simone, Thieme, Detlef, Thieme Detlef, Choukèr Alexander, Schelling Gustav, Feuerecker Matthias, Michael Vogeser, Kaufmann Ines, Vogeser Michael, Manfred Thiel, Schelling, Gustav, Vogeser, Michael, Choukèr, Alexander, Detlef Thieme, Thiel, Manfred, Gustav Schelling, Alexander Choukèr, Daniela Hauer, Thiel Manfred, Hauer, Daniela, Simone Kreth, Hauer Daniela   +26 more
core   +2 more sources

Omission of dexamethasone in prophylaxis for highly emetogenic chemotherapy in patients with breast cancer [PDF]

Einstein (São Paulo)
Objective Chemotherapy-induced nausea and vomiting are highly prevalent adverse events that can lead to poor treatment adherence and a decreased quality of life.
Camilla Vieira de Rebouças, Rafaela de Brito Alves, Alayne Magalhães Trindade Domingues Yamada, Auro del Giglio, Felipe José Silva Melo Cruz   +4 more
doaj   +1 more source