Results 71 to 80 of about 35,499 (199)

Glofitamab in combination with immunochemotherapy in patients with relapsed/refractory B‐cell non‐Hodgkin lymphoma: Phase 1b dose‐escalation study

British Journal of Haematology, EarlyView.
Summary Glofitamab was investigated with obinutuzumab/rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone (G/R‐CHOP) in patients with relapsed/refractory B‐cell non‐Hodgkin lymphoma (B‐NHL) who had ≥1 prior obinutuzumab/rituximab‐containing therapy (NCT03467373). The primary end‐point was to determine the optimal biological dose of
William Townsend, Nilanjan Ghosh, Martin Hutchings, Michael Dickinson, Monica Tani, Armando Santoro, Michael Crump, Amitkumar Mehta, Reinhard Marks, Martin Weisser, Martin Barrett, Chun Wu, Derrick Kaufman, Katharina Lechner, Pauline Baumlin, Pontus Lundberg, Max S. Topp   +16 more
wiley   +1 more source

Management of chemotherapy-induced nausea and vomiting by risk profile: role of netupitant/palonosetron [PDF]

, 2016
Vito Lorusso National Cancer Research Centre, Istituto Tumori Giovanni Paolo II, Bari, Italy Abstract: As recommended by most recent antiemetic guidelines, the optimal prophylaxis of chemotherapy-induced nausea and vomiting (CINV) requires the ...
Lorusso V
core  

Olanzapine for Chemotherapy-Induced Nausea and Vomiting [PDF]

, 2016
Excerpt: Navari and colleagues (July 14 issue)1 report on the use of olanzapine for the prevention of chemotherapy-induced nausea and ...
Bossaer, John B.
core   +1 more source

Olanzapine enhances the effect of conventional drugs in chemotherapy induced nausea and vomiting: A randomized clinical trial

Caspian Journal of Internal Medicine, 2022
Background: Chemotherapy inducing nausea and vomiting (CINV) is one of the significant   side  effects of anti-cancer treatment, and its full prevention is a potential challenge.
Atefe Khani, Ali Eishy Oskuyi, Rahim Asghari, Hamid Reza Khalkhali, Hamdollah Sharifi   +4 more
doaj  

Effect of Ginger Intake on Chemotherapy- Induced Nausea and Vomiting among Patients with Bladder Cancer [PDF]

Egyptian Journal of Health Care
Background: Chemotherapy-induced nausea and vomiting (CINV) is constitutes a major challange for patients with bladder cancer, frequently inadequately controlled by standared antiematic, ginger has historically been explored as an adjunctive therapy to ...
Sarah Mahmoud Ahmed Boriqa, Ahmed Abd El-Shafy, Raghda Yahia Abu El-Ela, Salwa Attia Mohamed Ahmed   +3 more
doaj   +1 more source

A phase IIa study of the anti‐PD‐L1 antibody avelumab in relapsed/refractory PTCL: The AVAIL‐T trial

British Journal of Haematology, EarlyView.
The AVAIL‐T study, the first evaluation of programmed death ligand 1 (PD‐L1) blockade in relapsed/refractory peripheral T‐cell lymphomas (PTCL), demonstrated limited single agent activity with durable responses seen in a minority. Circulating tumour DNA revealed distinct mutational dynamics and mass cytometry identified perturbed T‐cell subsets ...
Matthew J. Ahearne, Matthew A. Timmins, Charlotte Gaskell, Aimee Jackson, Clare Morland, Sonia Fox, Louise Hopkins, Nadia Nawaz, Susann Lehmann, Marc Wadsley, Caroline Cowley, Jacqueline Shaw, Naeem Khan, Nagesh Kalakonda, Christopher Trethewey, Ram Malladi, Paul Fields, Dima El Sharkawi, Michael Quinn, Nimish Shah, Andrew Davies, Kim Linton, Pam McKay, Rod Johnson, Simon D. Wagner, David Lewis, Graham P. Collins, Christopher P. Fox, Kate Cwynarski   +28 more
wiley   +1 more source

Effect of Peppermint Inhalation on Chemotherapy Induced-Nausea and Vomiting in Children with Leukemia [PDF]

Alexandria Scientific Nursing Journal
Background: Today, leukemia is one of the most important health challenges in the world. Despite the many advances in malignancy treatment, children undergoing chemotherapy are still suffering from deliberating side effects. So, pediatric oncology nurses
Eman Arafa Badr, Hawaa Mohamed Hassan, Youssr Abd-Elsalam Gaafer, Maha Youssef Kamal   +3 more
doaj   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

Therapeutic access points: The roles of circumventricular organs in drug delivery and metabolic regulation

British Journal of Pharmacology, EarlyView.
The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral, Nicholas Monaco, Daniel I. Brierley, Monica Imbernon   +3 more
wiley   +1 more source

Psychometric assessment of the Chinese version of the MASCC Antiemesis Tool (MAT) for measuring chemotherapy-induced nausea and vomiting

, 2016
Purpose: This paper aims to assess the psychometric properties of the Chinese version of the MASCC Antiemesis Tool (MAT) for measuring chemotherapy-induced nausea and vomiting (CINV).Methods: This was a psychometric study using a panel of experts and a ...
Tan, JY, Molassiotis, Alex, Molassiotis, A, Suen, L.K.P., Molasiotis, A., Tan, J.-Y., Suen, Lorna, Tan, Jing-Yu, Suen, LKP   +8 more
core   +1 more source