Results 81 to 90 of about 35,499 (199)

Pronounced Reductions in Plasma Citrulline Indicate Severe Intestinal Mucosal Barrier Injury During Induction Therapy for Pediatric Acute Myeloid Leukemia

European Journal of Haematology, EarlyView.
ABSTRACT Objectives Pediatric acute myeloid leukemia (AML) chemotherapy regimens are frequently burdened by fever episodes, systemic inflammation and bloodstream infections (BSI). Mucosal barrier injury may contribute to these complications, but its role in childhood AML remains uninvestigated.
Carla Warley Kjær, Maria Ebbesen Sørum, Silvia De Pietri, Claus Moser, Malene Johanne Petersen, Marianne Hoffmann, Henrik Hasle, Sarah Weischendorff, Klaus Müller   +8 more
wiley   +1 more source

Risk Factors Associated with Chemotherapy-Induced Nausea and Vomiting Among Women with Breast Cancer Receiving Highly Emetogenic Chemotherapy:Individual Patient-Based Analysis of Three Prospective Antiemetic Trials [PDF]

Purpose: Although risk factors related to chemotherapy-induced nausea and vomiting (CINV) have been identified in previous studies, only a few studies have evaluated the risk factors associated with contemporary antiemetic prophylaxis, including ...
Mo, Frankie K.F., Lau, Thomas K.H., Ko, Jonathan W.H., Ngai, Nicole T.Y., Kwok, Carol Chi Hei, Yeo, Horatio L., Yip, Claudia H.W., Molassiotis, Alex, Yip, CHristopher C.H., Pang, Elizabeth, Yeo, Winnie, Ko, Stephanie W.Y., Yeo, Victoria A., Lai, Kwai Tung, Li, Leung V.   +14 more
core   +1 more source

Malnutrition and chemotherapy-induced nausea and vomiting: implications for practice [PDF]

, 2012
Purpose/Objectives: To determine the prevalence of malnutrition and chemotherapy-induced nausea and vomiting (CINV) limiting patients' dietary intake in a chemotherapy unit. Design: Cross-sectional descriptive audit. Setting: Chemotherapy ambulatory care
McCarthy, Alexandra Leigh, Ferguson, Maree, Isenring, Elisabeth, Vick, Joanna, McCarthy, Alexandra, Isenring, Elisabeth A., Davidson, Wendy, Muller, Jacqueline, McCarthy, Alexandra L., Teleni, Laisa, Vick, Jo   +10 more
core   +1 more source

Comparison of intestinal histopathological changes following teclistamab, BCMA‐directed CAR T, CD19‐directed CAR T and rituximab therapies

Histopathology, EarlyView.
This is a retrospective review of intestinal tract biopsies from patients treated with various cellular immunotherapies (BCMA and CD19‐directed CAR T, teclistamab and rituximab therapies). We found distinct but overlapping histologic patterns across treatment groups, with lamina propria plasma cell depletion, crypt apoptotic bodies and active ...
Olivia J Leung, Esther Baranov, Isairis Peralta Valerio, Robin Collingwood, Natalie Respond, Don Siegel, Pooja Devi, Kristen M. Stashek   +7 more
wiley   +1 more source

Effect of non-pharmacological interventions on chemotherapy induced delayed nausea and vomiting for tumors: A systematic review and Bayesian network meta-analysis

Complementary Therapies in Medicine
Objective: To evaluate the efficacy of non-pharmacological interventions in improving chemotherapy induced delayed nausea and vomiting symptoms using a network meta-analysis. Methods: Four Chinese databases (CNKI, Wanfang Data Knowledge Service Platform,
Yongni Wang, Fang Wang, Feifei Hu, Fang Long   +3 more
doaj   +1 more source

Ramosetron hydrochloride for the prevention of cancer chemotherapy induced nausea and vomiting: The Indian experience

South Asian Journal of Cancer, 2014
Background: Despite the advent of 5-HT 3 antagonists, control of delayed gastrointestinal adverse events with cancer chemotherapy is still not optimal.
Jayesh J Sanmukhani, Prafulla Pawar, Ravindra Mittal   +2 more
doaj   +1 more source

Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy

Immunology &Cell Biology, EarlyView.
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley   +1 more source

International antiemetic guidelines on chemotherapy induced nausea and vomiting (CINV) : content and implementation in daily routine practice

, 2014
Over the past decades major improvements in the management of chemotherapy induced nausea and vomiting (CINV) were obtained. With the correct use of antiemetic drugs, CINV can be prevented in almost 70%, and even up to, 80% of patients.
Gralla, R, Molassiotis, A, Molasiotis, A., Jahn, F., Jahn, F, Gralla, R., Jordan, K, Jordan, K.   +7 more
core   +1 more source

Cancer co‐medication quality in older patients with polypharmacy: A large randomized trial testing a medication review versus usual care

Journal of Internal Medicine, EarlyView.
Abstract Background Evidence from randomized controlled trials (RCTs) testing medication reviews in geriatric oncology is sparse. Methods We conducted a single‐blinded RCT in ten rehabilitation clinics across Germany. Patients with common cancers, aged ≥ 65 years, and polypharmacy (regularly ≥ five drugs) were randomly allocated in equal proportions to
Miriam Degen, Annette Kopp‐Schneider, Tomislav Vlaski, Sigrid Carlsson, Peter Hallermann, Ludmilla Jewlanowa, Jana Barinoff, Valentin Goede, Christian Lüders, Thomas Kiefer‐Trendelenburg, Diana Lüftner, Jasmin Doll, Jürgen Wagner, Birgit Leibbrand, Hermann Brenner, Ben Schöttker   +15 more
wiley   +1 more source

The Effectiveness of P6 and Auricular Acupressure as a Complimentary Therapy in Chemotherapy-Induced Nausea and Vomiting Among Patients With Cancer: Systematic Review

Integrative Cancer Therapies
Background: Chemotherapy-induced nausea and vomiting (CINV) is one of the most prevalent and distressing side effects of chemotherapy among patients with cancer worldwide.
Bushra Alhusamiah MSN, PhD, Jumana Almomani MSN, PhD, Ahmad Al Omari MSN, PhD, Ala’a Abu attallah MSN, PhD, Afaf Yousef MSN, PhD, Jafar Alasad Alshraideh PhD, Ruqayya S. Zeilani PhD   +6 more
doaj   +1 more source