Enhancement of chemotherapy using oncolytic virotherapy: Mathematical and optimal control analysis [PDF]
Oncolytic virotherapy (OV) has been emerging as a promising novel cancer treatment that may be further combined with the existing therapeutic modalities to enhance their effects.
Eladdadi, Amina+4 more
core +2 more sources
Robust Individual Circadian Parameter Estimation for Biosignal-based Personalisation of Cancer Chronotherapy [PDF]
In cancer treatment, chemotherapy is administered according a constant schedule. The chronotherapy approach, considering chronobiological drug delivery, adapts the chemotherapy profile to the circadian rhythms of the human organism. This reduces toxicity
Arbaud, Alexandre+5 more
core +1 more source
In vitro activity of biapenem and other carbapenems against Russian clinical isolates of Pseudomonas aeruginosa, Acinetobacter spp., and Enterobacterales [PDF]
Objective. To evaluate in vitro activity of biapenem and other clinically available carbapenems against Russian clinical isolates of Enterobacterales, Pseudomonas aeruginosa и Acinetobacter spp., including isolates with acquired fermentative mechanisms ...
Kozlov R.S.+9 more
doaj +1 more source
AMRmap – antibiotic resistance surveillance system in Russia [PDF]
Objective. To review the basic principles and functionality of the AMRmap online resource. Materials and Methods. The AMRmap platform was developed using the R programming language and various downloadable modules – packages.
Kuzmenkov A.Yu.+6 more
doaj +1 more source
In vitro activity of cefpodoxime against Russian clinical isolates of Haemophilus influenzae, Streptococcus pneumoniae and Streptococcus pyogenes [PDF]
Objective. To determine in vitro activity of oral III generation cephalosporin cefpodoxime against clinical isolates of Haemophilus influenzae, Streptococcus pneumoniae and Streptococcus pyogenes isolated from patients with community-acquired ...
Kozlov R.S.+6 more
doaj +1 more source
In vitro activity of thiamphenicol against Haemophilus influenzae, Streptococcus pneumoniae and Streptococcus pyogenes clinical isolates [PDF]
Objective. To determine in vitro activity of thiamphenicol and other clinically available antimicrobials against clinical isolates of Haemophilus influenzae, Streptococcus pneumoniae and Streptococcus pyogenes. Materials and Methods.
Ivanchik N.V.+5 more
doaj +1 more source
Practice of local antibiotic resistance monitoring at hospitals in various regions of the Russian Federation [PDF]
Objective. To analyze the features of local antibiotic resistance monitoring at hospitals in the Russian Federation. Materials and Methods. The study involved a survey of 305 institutions.
Kuzmenkov A.Yu.+3 more
doaj +1 more source
AMRexpert – online platform for interpretation, verification and validation of antimicrobial susceptibility testing [PDF]
Objective. To review the key principles and functionality of AMRexpert online platform. Materials and Methods. The information part of the platform is comprised of rules based on the EUCAST recommendations and various standards for interpreting the ...
Vinogradova A.G.+5 more
doaj +1 more source
AMRcloud: a new paradigm in monitoring of antibiotic resistance [PDF]
Antimicrobial resistance is a growing threat to global public health and requires closer attention from the medical community. Antibiotic resistance monitoring systems play a key role in observing the antimicrobial susceptibility changes for rational ...
Kuzmenkov A.Yu.+6 more
doaj +1 more source
Pneumococcal vaccination in adult patients with comorbidities: a review of the clinical practice guidelines [PDF]
The review discusses national clinical practice guidelines for pneumococcal vaccination in different countries, existing approaches to adult immunization, and highlights key results of the most significant clinical studies and metaanalyses on the ...
Kozlov R.S.+3 more
doaj +1 more source