Results 191 to 200 of about 2,075,344 (349)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Characteristics, treatment, and outcome of recurrent gastro-oesophageal adeno-carcinoma after perioperative chemotherapy and radical resection. [PDF]

Acta Oncol
Larsen AC, Shim S, Bæksgaard L, Pfeiffer P, Nordsmark M, Sørensen JR, Brøndum R, Motavaf AK, Ladekarl M.   +8 more
europepmc   +1 more source

Measuring health-related quality of life in clinical trials that evaluate the role of chemotherapy in cancer treatment.

, 1998
M Michael, I. F. Tannock
openalex   +1 more source

Targeting Metabolic Adaptation of Colorectal Cancer with Vanadium‐Doped Nanosystem to Enhance Chemotherapy and Immunotherapy

Qian Cheng, Yuzhe Chen, Danyi Zou, Qilin Li, Xiaolei Shi, Qiang Qin, Miaodeng Liu, Lin Wang, Zheng Wang   +8 more
openalex   +1 more source

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

Science, 2009
K. Olive, Michael A. Jacobetz, Christian J. Davidson, A. Gopinathan, D. McIntyre, D. Honess, B. Madhu, M. Goldgraben, Meredith E. Caldwell, D. Allard, K. Frese, G. DeNicola, C. Feig, C. Combs, Stephen P. Winter, Heather Ireland-Zecchini, S. Reichelt, W. Howat, A.-L. Chang, M. Dhara, Lifu Wang, F. Rückert, R. Grützmann, C. Pilarsky, K. Izeradjene, S. Hingorani, Pearl S Huang, S. Davies, W. Plunkett, M. Egorin, R. Hruban, Nigel Whitebread, Karen McGovern, J. Adams, C. Iacobuzio-Donahue, J. Griffiths, D. Tuveson   +36 more
semanticscholar   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Long-term follow-up of predominantly Asian patients with relapsed/refractory FLT3-mutated acute myeloid leukemia in the phase 3 COMMODORE trial. [PDF]

Ann Hematol
Jiang B, Li J, Liu L, Du X, Jiang H, Hu J, Zeng X, Sakatani T, Kosako M, Deng Y, Ivanov V, Bondarenko S, Lee Lee LW, Khuhapinant A, Martynova E, Hasabou N, An JJ, Wang J.   +17 more
europepmc   +1 more source

P1350: THE EFFICACY OF UPFRONT HIGH-DOSE CHEMOTHERAPY WITH AUTOLOGOUS STEM CELL TRANSPLANTATION IN DECREASING RELAPSE RATE IN IV STAGE AND HIGH-INTERMEDIATE/HIGH IPI RISK GROUPS DLBCL

, 2022
A. Koviazin, Л. В. Филатова, I. Zyuzgin, A. Artemyeva, M. Motalkina, Y. Chudinovskikh, S. Volchenkov, I. Poliatskin, E. Dobrovolskaya, S. Shalaev, I. Ishmatova, A. Zverkova, D. Burda, S. Elkhova, Т. Yu. Semiglazova   +14 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Ceftazidime-Induced Overexpression of MexJK-OprM Confers Resistance to Ceftolozane/Tazobactam in an Isolate of Pseudomonas aeruginosa

Infection and Drug Resistance
Takumi Sato,1 Mai Tamura,2,3 Kei Kaimori,1 Fumihiko Okumura,4 Shin Ikejima,3 Hajime Nakai,2,3 Masato Kawamura,1 Shigeru Fujimura1 1Division of Clinical Infectious Diseases & Chemotherapy, Graduate School of Pharmaceutical Sciences, Tohoku Medical and
Sato T, Tamura M, Kaimori K, Okumura F, Ikejima S, Nakai H, Kawamura M, Fujimura S   +7 more
doaj