Candidate genes in gastric cancer identified by constructing a weighted gene co-expression network [PDF]
Background Gastric cancer (GC) is one of the most common cancers with high mortality globally. However, the molecular mechanisms of GC are unclear, and the prognosis of GC is poor.
Jian Chen+5 more
doaj +2 more sources
Induction chemotherapy in the treatment of nasopharyngeal carcinoma: Clinical outcomes and patterns of care [PDF]
The role of induction chemotherapy in nasopharyngeal carcinoma (NPC) remains controversial. The primary aim of this study was to use the National Cancer Database to evaluate the patterns of care of induction chemotherapy in NPC and its impact on overall ...
Adkins, Douglas+10 more
core +2 more sources
Breast cancer: Monitoring response to neoadjuvant chemotherapy using Tc-99m sestamibi scintimammography [PDF]
Background: Aim of the study was to assess the value of scintimammography using Tc-99m sestamibi in the evaluation of tumor response to neoadjuvant chemotherapy.
Brinkbäumer, K.+6 more
core +1 more source
The known-unknown: third- and fourth-generation cephalosporins combined with sulbactam [PDF]
Despite the presence of more than 100 different antibacterials in the therapeutic arsenal, beta-lactam antibiotics, in general, and the third-generation cephalosporins, in particular, remain the main option for the treatment of the most of infections in ...
Stetsiouk O.U.+3 more
doaj +1 more source
Medication use by early-stage breast cancer survivors: a 1-year longitudinal study. [PDF]
PurposeThe aim of this study is to characterize the patterns of medication use by early-stage breast cancer (ESBC) survivors from diagnosis to 1 year post-chemotherapy.MethodsA single-center longitudinal study was conducted with ESBC patients diagnosed ...
Chan, Alexandre+4 more
core +1 more source
Ceftazidimeavibactam use in children and adolescents [PDF]
The increasing number of infections caused by multidrug-resistant gram-negative bacteria in children is a serious problem all over the world. Ceftazidim-avibactam is a promising antimicrobial drug recently approved in Russia for use in pediatric practice.
Stetsiouk О.U.+3 more
doaj +1 more source
A Retrospective Analysis using Deep-Learning Models for Prediction of Survival Outcome and Benefit of Adjuvant Chemotherapy in Stage II/III Colorectal Cancer [PDF]
Most early-stage colorectal cancer (CRC) patients can be cured by surgery alone, and only certain high-risk early-stage CRC patients benefit from adjuvant chemotherapies. However, very few validated biomarkers are available to accurately predict survival benefit from postoperative chemotherapy.
arxiv
Supplemental prophylactic intervention for chemotherapy-induced nausea and emesis (spice) trial: Protocol for a multi-centre double-blind placebo-controlled randomized trial [PDF]
Aim: There is significant recent interest in the role of ginger root (Zingiber officinale) as an adjuvant therapy for chemotherapy‐induced nausea. The supplemental prophylactic intervention for chemotherapy‐induced nausea and emesis (SPICE) trial aims
Bird, Robert+8 more
core +1 more source
Combination Chemotherapy Optimization with Discrete Dosing [PDF]
Chemotherapy is one of the primary modalities of cancer treatment. Chemotherapy drug administration is a complex problem that often requires expensive clinical trials to evaluate potential regimens. One way to alleviate this burden and better inform future trials is to build reliable models for drug administration.
arxiv