Results 41 to 50 of about 2,023,245 (348)

AMRmap: an online platform for monitoring antibiotic resistance [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
This review describes the new Internet resource AMRmap (map.antibiotic.ru), which provides data on antibiotic resistance in the Russian Federation.
Kuzmenkov A.Yu., Trushin I.V., Avramenko A.A., Edelstein M.V., Dekhnich A.V., Kozlov R.S.   +5 more
doaj  

Antimicrobial resistance of nosocomial Enterobacteriaceae isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014 [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
Species of the family Enterobacteriaceae represent the most prevalent group of nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 1670 isolates of Enterobacteriaceae collected in 35 hospitals of 22 cities of Russia
Sukhorukova M.V., Edelstein M.V., Skleenova E.Yu., Ivanchik N.V., Mikotina A.V., Dekhnich A.V., Kozlov R.S., «MARATHON» Study Group   +7 more
doaj  

Adjuvant Chemotherapy Guided by a 21‐Gene Expression Assay in Breast Cancer

New England Journal of Medicine, 2018
BACKGROUND The recurrence score based on the 21‐gene breast cancer assay predicts chemotherapy benefit if it is high and a low risk of recurrence in the absence of chemotherapy if it is low; however, there is uncertainty about the benefit of chemotherapy
J. Sparano, R. Gray, D. Makower, K. Pritchard, K. Albain, D. Hayes, C. Geyer, E. Dees, M. Goetz, J. Olson, T. Lively, S. Badve, T. Saphner, L. Wagner, T. Whelan, M. Ellis, S. Paik, W. Wood, P. Ravdin, M. Keane, H. G. Gomez Moreno, P. Reddy, T. Goggins, I. Mayer, A. Brufsky, D. Toppmeyer, V. Kaklamani, J. Berenberg, J. Abrams, G. Sledge   +29 more
semanticscholar   +1 more source

Cemiplimab plus chemotherapy versus chemotherapy alone in non-small cell lung cancer: a randomized, controlled, double-blind phase 3 trial

Nature Network Boston, 2022
First-line cemiplimab (anti-programmed cell death-1 (PD-1)) monotherapy has previously shown significant improvement in overall survival (OS) and progression-free survival (PFS) versus chemotherapy in patients with advanced non-small cell lung cancer ...
M. Gogishvili, T. Melkadze, Tamta Makharadze, D. Giorgadze, M. Dvorkin, K. Penkov, K. Laktionov, G. Nemsadze, M. Nechaeva, I. Rozhkova, E. Kalinka, C. Gessner, B. Moreno-Jaime, R. Passalacqua, Siyu Li, K. McGuire, M. Kaul, A. Paccaly, R. Quek, Bo Gao, F. Seebach, D. Weinreich, G. Yancopoulos, I. Lowy, G. Gullo, P. Rietschel   +25 more
semanticscholar   +1 more source

Antimicrobial resistance of nosocomial Pseudomonas aeruginosa isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014 [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
Pseudomonas aeruginosa is the most abundant bacterial species causing nosocomial infections in Russia. In this paper, we report the data on antimicrobial susceptibility of 743 isolates of P.
Edelstein M.V., Sukhorukova M.V., Skleenova E.Yu., Ivanchik N.V., Mikotina A.V., Shek E.A., Dekhnich A.V., Azyzov I.S., Kozlov R.S., «MARATHON» Study Group   +9 more
doaj  

Antimicrobal resistance of nosocomial carbapenemase-producing Enterobacterales in Russia: results of surveillance, 2014-2016 [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2018
Objective. To assess the prevalence and antimicrobial susceptibility of carbapenemase-producing Enterobacterales (CPE). Materials and Methods. A total of 5539 Enterobacterales isolates recovered from hospitalized patients in 52 medical institutions ...
Shajdullina E.R., Edelstein M.V., Skleenova E.Yu., Sukhorukova M.V., Kozlov R.S.   +4 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Antimicrobial resistance of nosocomial Acinetobacter spp. isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014 [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
Acinetobacter baumannii and related species of the A. baumannii complex are the common and one of the most difficult-to-treat nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 568 isolates of Acinetobacter spp ...
Sukhorukova M.V., Edelstein M.V., Skleenova E.Yu., Ivanchik N.V., Shek E.A., Dekhnich A.V., Kozlov R.S., «MARATHON» Study Group   +7 more
doaj  

Effect of Camrelizumab vs Placebo Added to Chemotherapy on Survival and Progression-Free Survival in Patients With Advanced or Metastatic Esophageal Squamous Cell Carcinoma: The ESCORT-1st Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2021
Importance Standard first-line therapy for advanced or metastatic esophageal carcinoma is chemotherapy, but the prognosis remains poor. Camrelizumab (an anti-programmed death receptor 1 [PD-1] antibody) showed antitumor activity in previously treated ...
Hui‐yan Luo, J. Lu, Y. Bai, T. Mao, Jun Wang, Q. Fan, Yiping Zhang, K. Zhao, Zhendong Chen, Shegan Gao, Jiancheng Li, Z. Fu, K. Gu, Zhihua Liu, Lin Wu, Xiaodong Zhang, Jifeng Feng, Z. Niu, Y. Ba, He-long Zhang, Ying Liu, Li Zhang, X. Min, Jing Huang, Ying Cheng, Dong Wang, Yuzhen Shen, Qing Yang, J. Zou, Rui-Hua Xu   +29 more
semanticscholar   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source