Results 41 to 50 of about 2,047,581 (349)

Antimicrobial resistance of nosocomial Pseudomonas aeruginosa isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014 [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
Pseudomonas aeruginosa is the most abundant bacterial species causing nosocomial infections in Russia. In this paper, we report the data on antimicrobial susceptibility of 743 isolates of P.
Edelstein M.V., Sukhorukova M.V., Skleenova E.Yu., Ivanchik N.V., Mikotina A.V., Shek E.A., Dekhnich A.V., Azyzov I.S., Kozlov R.S., «MARATHON» Study Group   +9 more
doaj  

Antimicrobal resistance of nosocomial carbapenemase-producing Enterobacterales in Russia: results of surveillance, 2014-2016 [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2018
Objective. To assess the prevalence and antimicrobial susceptibility of carbapenemase-producing Enterobacterales (CPE). Materials and Methods. A total of 5539 Enterobacterales isolates recovered from hospitalized patients in 52 medical institutions ...
Shajdullina E.R., Edelstein M.V., Skleenova E.Yu., Sukhorukova M.V., Kozlov R.S.   +4 more
doaj   +1 more source

Antimicrobial resistance of nosocomial Acinetobacter spp. isolates in Russia: results of multicenter epidemiological study «MARATHON» 2013-2014 [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2017
Acinetobacter baumannii and related species of the A. baumannii complex are the common and one of the most difficult-to-treat nosocomial pathogens. In this paper, we report the data on antimicrobial susceptibility of 568 isolates of Acinetobacter spp ...
Sukhorukova M.V., Edelstein M.V., Skleenova E.Yu., Ivanchik N.V., Shek E.A., Dekhnich A.V., Kozlov R.S., «MARATHON» Study Group   +7 more
doaj  

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Adjuvant Chemotherapy Guided by a 21‐Gene Expression Assay in Breast Cancer

New England Journal of Medicine, 2018
BACKGROUND The recurrence score based on the 21‐gene breast cancer assay predicts chemotherapy benefit if it is high and a low risk of recurrence in the absence of chemotherapy if it is low; however, there is uncertainty about the benefit of chemotherapy
J. Sparano, R. Gray, D. Makower, K. Pritchard, K. Albain, D. Hayes, C. Geyer, E. Dees, M. Goetz, J. Olson, T. Lively, S. Badve, T. Saphner, L. Wagner, T. Whelan, M. Ellis, S. Paik, W. Wood, P. Ravdin, M. Keane, H. G. Gomez Moreno, P. Reddy, T. Goggins, I. Mayer, A. Brufsky, D. Toppmeyer, V. Kaklamani, J. Berenberg, J. Abrams, G. Sledge   +29 more
semanticscholar   +1 more source

21-Gene Assay to Inform Chemotherapy Benefit in Node-Positive Breast Cancer.

New England Journal of Medicine, 2021
BACKGROUND The recurrence score based on the 21-gene breast-cancer assay has been clinically useful in predicting a chemotherapy benefit in hormone-receptor-positive, human epidermal growth factor receptor 2 (HER2)-negative, axillary lymph-node-negative ...
K. Kalinsky, W. Barlow, J. Gralow, F. Meric-Bernstam, K. Albain, D. Hayes, N. Lin, E. A. Perez, L. Goldstein, S. Chia, S. Dhesy-Thind, Priya Rastogi, E. Alba, S. Delaloge, Miguel Martín, C. Kelly, M. Ruíz-Borrego, M. Gil-Gil, C. Arce‐Salinas, E. Brain, Eun-Sook Lee, J. Pierga, B. Bermejo, Manuel Ramos-Vázquez, K. Jung, J. Ferrero, A. Schott, S. Shak, Priyanka Sharma, D. Lew, Jieling Miao, D. Tripathy, L. Pusztai, G. Hortobagyi   +33 more
semanticscholar   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Inhibition of anti-apoptotic Bcl-2 family members promotes synergistic cell death with ER stress inducers by disrupting autophagy in glioblastoma

Cell Death Discovery
Glioblastoma (GBM) remains one of the most aggressive and challenging brain tumors. Unfortunately, current clinical treatment options offer limited efficacy, highlighting the necessity for uncovering novel therapeutic strategies.
Tianyi Huang, Satoshi Takagi, Sumie Koike, Ryohei Katayama   +3 more
doaj   +1 more source

Antimicrobial Resistance of Gram-negative Microorganisms Causing Complicated Intra-abdominal Infections in Russia [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2015
Objective. To assess antimicrobial resistance of gram-negative microorganisms causing complicated intra-abdominal infections (IAI) in Russia. Materials and Methods.
Kozlov R.S., Golub A.V., Dekhnich A.V., Sukhorukova M.V., SMART Study Group   +4 more
doaj  

Role of endogenous and exogenous antioxidants in risk of six cancers: evidence from the Mendelian randomization study

Frontiers in Pharmacology, 2023
Background: Although oxidative stress is known to contribute to cancer, and endogenous and exogenous antioxidants are thought to prevent tumorigenesis by suppressing oxidative stress-induced DNA damage, antioxidants have also been reported to show ...
Jiahao Zhu, Jie Lian, Xin Wang, Ren Wang, Xiangyi Pang, Benjie Xu, Xing Wang, Chenyang Li, Shengjun Ji, Haibo Lu   +9 more
doaj   +1 more source