Results 241 to 250 of about 12,690 (274)

Natural products as a source of new anticancer chemotypes

Expert Opinion on Therapeutic Patents, 2023
Exploring the chemical diversity and molecular mechanisms of natural products continues to be an important research area for identifying novel promising therapeutic approaches for fighting cancer. This is a complex disease and poses important challenges, which require not only targeted interventions to improve chemotherapy efficacy and tolerability ...
Melfi F., Carradori S., Mencarelli N., Campestre C., Gallorini M., Di Giacomo S., Di Sotto A.   +6 more
openaire   +2 more sources

Studies on Chemotypes of Cinnamomum Camphora

Advanced Materials Research, 2011
Gas chromatography coupled with mass spectrometry (GC-MS) was applied to analyze the essential oil extracted from the leaves of 50 individual plants of Cinnamomum camphora, which were collected from the same mountain in Jiangxi province of China. 32 peaks in total were identified in these samples, which were then categorized into five chemotypes ...
Yong Ming Luo, Shi Rong Li, Xiao Yin Yin
openaire   +1 more source

A chemotype of Cyperus rotundus in Hawaii

Phytochemistry, 1989
Abstract A new chemotype of Cyperus rotundus was found in Hawaii based on the sesquiterpene composition of the mature tubers. The K-type has higher concentrations of patchoulenyl acetate and sugeonyl acetate than the three known Asian chemotypes. Biochemical and evolutionary aspects of these findings are discussed.
Koichiro Komai, Chung-Shih Tang
openaire   +1 more source

Population Structure, Chemotype Diversity, and Potential Chemotype Shifting of Fusarium graminearum in Wheat Fields of Manitoba

Plant Disease, 2008
This study was to investigate the variation of acetyl ester derivative of DON at 15-position oxygen (15ADON) and acetyl ester derivative of DON at 3-position oxygen (3ADON) chemotypes and potential chemotype shifting of Fusarium graminearum based on the population structure of this species in Manitoba.
X W, Guo, W G D, Fernando, H Y, Seow-Brock   +2 more
openaire   +2 more sources

Benzoxaborole as a new chemotype for carbonic anhydrase inhibition

Chemical Communications, 2016
In this paper we provide the first experimental evidence that benzoxaboroles can be used as CA inhibitors.
Alterio Vincenzo, Cadoni Roberta, Esposito Davide, Vullo Daniela, Di Fiore Anna, Monti Simona Maria, Caporale Andrea, Ruvo Menotti, Sechi Mario, Dumy Pascal, Supuran Claudiu T, De Simone Giuseppina, Winum JeanYves   +12 more
openaire   +4 more sources

New withanolides from a cross of a South African chemotype by chemotype II (Israel) in Withania somnifera

Phytochemistry, 1980
Abstract Three new withanolides have been isolated from hybrids obtained by crossing a chemotype of Withania somnifera received from South Africa and chemotype II originating in Israel. The compounds have been characterized as 4β,20α-dihydroxy-1-oxo-5β,6β-epoxy-20 R ,22 R -witha-24-enolide, 20α-hydroxy-1,4-dioxo-5β,6β-epoxy-20 R ,22 R -witha-2,24 ...
Frank W. Eastwood, Isaac Kirson, David Lavie, Arieh Abraham   +3 more
openaire   +1 more source

Linked Chemotype Cellular Uptake Is Facilitated by IFITMs

Cancer Discovery, 2023
Abstract Interferon-induced transmembrane proteins (IFITM) modulate cell permeability of diverse linked chemotypes.
openaire   +2 more sources

Chemotypes of Tansy in Finland

Planta Medica, 1986
M, Holopainen, R, Hiltunen, M, V Schantz
openaire   +2 more sources

Pyrroloquinolone-Based Compounds as a Novel Antimycobacterial Chemotype

ACS Medicinal Chemistry Letters
Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), remains the world's most lethal infectious disease, posing an uncontained health challenge. The major hurdles are the long treatments and low patient compliance that leads to the appearance of resistance, as well as the lack of drugs that effectively tackle the latent infections.
Marta Clariano, Diogo Nunes, Daniela Canudo, Daniela Maçãs, Bruno J. L. Castro, Audrey Jordaan, Pedro Gomes, Anna Contini, João Perdigão, Isabel Portugal, Margarida Madureira, Digby F. Warner, Marco Pieroni, Maria de Jesus Perry, Francisca Lopes   +14 more
openaire   +2 more sources

Chemical Variability and Chemotype Concept of Essential Oils from Algerian Wild Plants

Molecules, 2023
Yacine Boumghar, Nassim Djabou
exaly