Results 231 to 240 of about 5,134,427 (306)

Chenodeoxycholic acid

Reactions Weekly, 2017
semanticscholar   +4 more sources

Chenodeoxycholic acid

Reactions Weekly, 2019
semanticscholar   +3 more sources

Chenodeoxycholic-acid

Reactions Weekly
openaire   +2 more sources

Chenodeoxycholic acid (CDCA) protects against the LPS-induced impairment of intestinal epithelial barrier function via FXR-MLCK pathway.

Journal of Agricultural and Food Chemistry, 2019
Chenodeoxycholic acid (CDCA), a primary bile acid, has been demonstrated to play important roles as signaling molecule in various physiology functions. However, the role of CDCA in regulating intestinal barrier function remains largely unknown.
Min Song, Jiayi Ye, Fenglin Zhang, Han Su, Xiaohua Yang, Haiwen He, Fangfang Liu, Xiaotong Zhu, Lina Wang, P. Gao, G. Shu, Q. Jiang, Songbo Wang   +12 more
semanticscholar   +1 more source

7-Methylation of Chenodeoxycholic Acid Derivatives Yields a Substantial Increase in TGR5 Receptor Potency.

Journal of Medicinal Chemistry, 2019
TGR5 agonists are potential therapeutics for a variety of conditions including type 2 diabetes, obesity, and inflammatory bowel disease. After screening a library of chenodeoxycholic acid (CDCA) derivatives, it was determined that a range of ...
A. Nakhi, Connor M. McDermott, Kristen L. Stoltz, Kristen John, J. Hawkinson, Elizabeth A Ambrose, A. Khoruts, M. Sadowsky, P. Dosa   +8 more
semanticscholar   +1 more source

Conversion of chenodeoxycholic acid to cholic acid by human CYP8B1

Biological chemistry, 2018
The human cytochrome P450 enzyme CYP8B1 is a crucial regulator of the balance of cholic acid (CA) and chenodeoxycholic acid (CDCA) in the liver. It was previously shown to catalyze the conversion of 7α-hydroxycholest-4-en-3-one, a CDCA precursor, to 7α ...
Linbing Fan, J. Joseph, P. Durairaj, M. Parr, M. Bureik   +4 more
semanticscholar   +1 more source

Restructuring of Dye Layers in Dye Sensitized Solar Cells: Cooperative Adsorption of N719 and Chenodeoxycholic Acid on Titania

ACS Applied Energy Materials, 2018
The effect of the co-adsorbent chenodeoxycholic acid (CDCA) up to a concentration of 20 mM on the adsorption of the dye N719 onto titania has been investigated using neutral impact collision ion sc ...
H. Trilaksana, C. Shearer, L. Kloo, G. Andersson   +3 more
semanticscholar   +1 more source

Hypertriglyceridaemia and Chenodeoxycholic Acid

1977
Abnormalities of lipoprotein metabolism are frequently found in patient with primary gout. The most common lipid abnormality is hypertriglyceridaemia, independent of, and not secondary to, either obesity, alcohol consumption, or carbohydrate intolerance (1,2).
R, Marcolongo, A, Debolini
openaire   +2 more sources

Solvolysis of chenodeoxycholic acid sulfates

Steroids, 1981
Chemical solvolysis of chenodeoxycholic acid sulfates was studied using 4 published methods. Quantitative recovery of chenodeoxycholic acid from the 3-sulfate was obtained with each method. However, only 2 methods yielded chenodeoxycholic acid after solvolysis of the 7-sulfate.
B I, Cohen, K, Budai, N B, Javitt
openaire   +2 more sources

Structure of chenodeoxycholic acid in chenodeoxycholic acid ethyl acetate solvate

Acta Crystallographica Section C Crystal Structure Communications, 1990
C 24 H 40 O 4 •C 4 H 8 O 2 cristallise dans P6 5 avec a=22,169, c=10,226 A, Z=6; affinement jusqu'a R=0,071. Les molecules acides chenodesoxycholiques sont arrangees en une chaine helicoidale autour de l'axe 6 5 , formant ainsi une colonne infinie. Les groupes hydrophiles externes de ces colonnes sont empiles parallelement l'un a l'autre et connectes
P. van der Sluis, A. Schouten, J. A. Kanters   +2 more
openaire   +1 more source