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Chenodeoxycholate: The Bile Acid. The Drug. A Review
The American Journal of the Medical Sciences, 1994Chenodeoxycholate (3 alpha, 7 alpha-dihydroxy-5 beta-cholanic acid) is a primary bile acid directly synthesized from cholesterol. It is an amphipathic molecule, possessing both a hydrophobic side and a polar hydrophilic side, giving it the ability to solubilize lipids in a water environment.
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A New Non-enzymatic Route to Chenodeoxycholic Acid
Chemistry Letters, 1996Abstract A novel route for the production of the chenodeoxycholic acid is described, based on the selective non-enzymatic reduction of dehydrocholic acid The relative reactivity scale was established to be in the order: 12-keto (1), 7-keto (2), 3-keto (17.5).
BORTOLINI, Olga +3 more
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GALLSTONE DISSOLUTION BY CHENODEOXYCHOLIC ACID
The Lancet, 1973G. Duncan Bell, R. Hermon Dowling
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Dissolution of Gallstones by Chenodeoxycholic Acid
1976In another chapter in this volume, Dr. Hofmann has discussed in detail newer aspects of bile acid physiology and of the enterohepatic circulation. The purpose of this chapter is to review the most important therapeutic advance in the bile acid field, namely the use of chenodeoxycholic acid (CDCA) in the treatment of gallstones.
Gerard M. Murphy +2 more
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An Improved Preparation of Chenodeoxycholic Acid
Journal of Natural Products, 1984Phillip Fraher +3 more
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Measurement of Chenodeoxycholic Acid and Deoxycholic Acid or their Derivatives in a Mixture
Nature, 1965THE measurement of the dihydroxycholanic acids found in human bile (chenodeoxycholic acid, 3α,7α-dihydroxycholanic acid and deoxycholic acid, 3α,12α-dihydroxycholanic acid) or of their ester derivatives or conjugates with glycine or taurine has always presented difficulties where the original material to be analysed contains both acids or derivatives ...
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Combination Therapy of Chenodeoxycholic Acid and Ursodeoxycholic Acid
1990Bile acid therapy has become well established as nonsurgical treatment in selected patients with cholesterol gallstones since chenodeoxycholic acid (cheno) and, later on, ursodeoxycholic acid (urso) were introduced in the early 1970s and 1980s, respectively.
Mauro Podda +5 more
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