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To Choose or Not to Choose: Patients with Chest Pain Often Do Not Choose to Triage for Chest Pain During Online Self-Triage [PDF]

Health Services Insights
Background: Patients performing self-triage for chest pain need to pick an algorithm which includes questions pertinent to chest pain to triage accurately.
Jennifer L. Pecina, Elizabeth N. Curry, Nathaniel E. Miller, Matthew C. Thompson, Frederick North   +4 more
doaj   +2 more sources

Rho A/ROCK1 signaling-mediated metabolic reprogramming of valvular interstitial cells toward Warburg effect accelerates aortic valve calcification via AMPK/RUNX2 axis

Cell Death and Disease, 2023
The aberrant differentiation of valvular interstitial cells (VICs) to osteogenic lineages promotes calcified aortic valves disease (CAVD), partly activated by potentially destructive hemodynamic forces.
Huiruo Liu, Hang Yin, Zhen Wang, Qiuhuan Yuan, Feng Xu, Yuguo Chen, Chuanbao Li   +6 more
doaj   +1 more source

Comparative effects of rosuvastatin and atorvastatin on the risk of new-onset diabetes mellitus in patients with acute coronary syndrome receiving percutaneous coronary intervention: a retrospective cohort study

Emergency and Critical Care Medicine, 2022
. Background. Statins are frequently prescribed to reduce cardiovascular morbidity and mortality by lowering low-density lipoprotein cholesterol levels.
Cunhui Jia, Rui Tian, Mengzhi Zong, Fangyun Luan, Wenjun Wang, Chuanbao Li   +5 more
doaj   +1 more source

The role of lipotoxicity in cardiovascular disease

Emergency and Critical Care Medicine, 2022
. Fatty acids are the primary fuel for cardiac muscle. The physiological equilibrium of lipid uptake and oxidation may aid in the prevention of excessive lipid accumulation.
Chuanbao Li, Huiruo Liu, Feng Xu, Yuguo Chen   +3 more
doaj   +1 more source

Evaluation and comparison of six GRACE models for the stratification of undifferentiated chest pain in the emergency department

BMC Cardiovascular Disorders, 2020
Background The Global Registry of Acute Coronary Events (GRACE) score is recommended for stratifying chest pain. However, there are six formulas used to calculate the GRACE score for different outcomes of acute coronary syndrome (ACS), including death ...
Wen Zheng, Guangmei Wang, Jingjing Ma, Shuo Wu, He Zhang, Jiaqi Zheng, Feng Xu, Jiali Wang, Yuguo Chen   +8 more
doaj   +1 more source

Short-term efficacy of angiotensin receptor-neprilysin inhibitor treatment in patients with ST-segment elevation myocardial infarction with reduced ejection fraction after primary percutaneous coronary intervention: a propensity score matching study

BMC Cardiovascular Disorders, 2022
Background Acute myocardial infarction (AMI) causes a series of pathophysiological changes, including myocardial necrosis, myocardial edema, and microvascular damage.
Qun Zhang, Bao Qiao, Yu Han, Shukun Sun, Bailu Wang, Shujian Wei   +5 more
doaj   +1 more source

Effect of preinitiated glucose-insulin-potassium strategy for patients with undergoing planned percutaneous coronary intervention: a systematic review and meta-analysis

BMJ Open, 2023
Objectives Whether the glucose-insulin-potassium (GIK) should be used as an adjuvant therapy for ischaemic myocardial disease remains controversial nowadays reperfusion era.
Feng Xu, Chuanbao Li, Huiruo Liu, Rugang Liu, Zeyu Yang   +4 more
doaj   +1 more source

Mortality in cardiogenic shock patients receiving mechanical circulatory support: a network meta-analysis

BMC Cardiovascular Disorders, 2022
Objective Mechanical circulatory support (MCS) devices are widely used for cardiogenic shock (CS). This network meta-analysis aims to evaluate which MCS strategy offers advantages.
Qun Zhang, Yu Han, Shukun Sun, Chuanxin Zhang, Han Liu, Bailu Wang, Shujian Wei   +6 more
doaj   +1 more source

Outcomes of Cerebral Embolic Protection for Bicuspid Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Replacement

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background There was limited high‐quality evidence that illuminated the efficiency of cerebral embolic protection (CEP) use during transcatheter aortic valve replacement (TAVR) for bicuspid aortic valve (BAV) stenosis.
Jiajun Zhang, Xiaoxing Li, Rui Tian, Mengzhi Zong, Xinghua Gu, Feng Xu, Yuguo Chen, Chuanbao Li   +7 more
doaj   +1 more source

Early Progression of Abdominal Aortic Aneurysm is Decelerated by Improved Endothelial Barrier Function via ALDH2‐LIN28B‐ELK3 Signaling

Advanced Science, 2023
The involvement of endothelial barrier function in abdominal aortic aneurysm (AAA) and its upstream regulators remains unknown. Single‐cell RNA sequencing shows that disrupted endothelial focal junction is an early (3 days) and persistent (28 days) event
Kehui Yang, Sumei Cui, Jingwen Wang, Tonghui Xu, Han Du, Hongwei Yue, Huaqing Ye, Jialin Guo, Jian Zhang, Pengpai Li, Yunyun Guo, Chang Pan, Jiaojiao Pang, Jiali Wang, Xiao Yu, Cheng Zhang, Zhiping Liu, Yuguo Chen, Feng Xu   +18 more
doaj   +1 more source