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Comparison of Chi-Separation and Chi-Separation*: A Clinical Feasibility Study
Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and ExhibitionWhile χ-separation gives unique and valuable information, requirement of R2 limited its clinical application. This study assessed the clinical feasibility of two R2*-based magnetic source separation. From 24 MR scans of MS subjects, four sets of magnetic source separation maps were generated; (1) χ-separation (originally proposed method), (2) χ ...
Hyeong-Geol Shin +2 more
exaly +2 more sources
ISMRM Annual Meeting, 2023
We develop pipelines for reconstructing susceptibility source separation (χ-separation) maps, which requires a T2 map, from UK Biobank protocol and routine clinical protocol data that have no T2 map but have various T2-weighted contrasts (e.g., FLAIR and T2-weighted images). Using these and additional contrast-weighted images, we propose a deep
Hwihun Jeong +3 more
openaire +1 more source
We develop pipelines for reconstructing susceptibility source separation (χ-separation) maps, which requires a T2 map, from UK Biobank protocol and routine clinical protocol data that have no T2 map but have various T2-weighted contrasts (e.g., FLAIR and T2-weighted images). Using these and additional contrast-weighted images, we propose a deep
Hwihun Jeong +3 more
openaire +1 more source
ISMRM Annual Meeting, 2023
Recently, the susceptibility source separation method, χ-separation, was suggested to separate paramagnetic and diamagnetic susceptibility distributions in the brain, potentially providing quantitative information of paramagnetic iron and diamagnetic myelin.
Hyeong-Geol Shin +12 more
openaire +1 more source
Recently, the susceptibility source separation method, χ-separation, was suggested to separate paramagnetic and diamagnetic susceptibility distributions in the brain, potentially providing quantitative information of paramagnetic iron and diamagnetic myelin.
Hyeong-Geol Shin +12 more
openaire +1 more source
Background R2* correction for χ-separation (chi-separation)
ISMRM Annual MeetingMotivation: An advanced quantitative susceptibility mapping (QSM) technique, χ-separation, requires tissue field map and R2* to separate paramagnetic and diamagnetic components. As the background field is removed to acquire the tissue field map, the background R2* needs to be removed to accurately estimate paramagnetic and diamagnetic ...
Kyeongseon Min, Jongho Lee
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A toolbox of chi-separation for magnetic susceptibility source separation
ISMRM Annual MeetingThe susceptibility maps generated by QSM and $$$\chi$$$-separation show magnetic susceptibility distributions, which have been proposed as important biomarkers for brain disorders. However, susceptibility mapping requires a complicated multi-step procedure that is difficult for inexperienced researchers.
Jun-Hyeok Lee +4 more
openaire +1 more source
ISMRM Annual Meeting
Motivation: Syndrome-specific patterns of iron-rich cortical gliosis have been demonstrated postmortem in Frontotemporal Lobal Degeneration (FTLD) but have not been reliably detected in vivo. Goal(s): Evaluate whether Chi-separation and/or Quantitative Susceptibility Mapping (QSM) can reliably detect regional changes in cortical paramagnetism in ...
Shraddha Pandey +6 more
openaire +1 more source
Motivation: Syndrome-specific patterns of iron-rich cortical gliosis have been demonstrated postmortem in Frontotemporal Lobal Degeneration (FTLD) but have not been reliably detected in vivo. Goal(s): Evaluate whether Chi-separation and/or Quantitative Susceptibility Mapping (QSM) can reliably detect regional changes in cortical paramagnetism in ...
Shraddha Pandey +6 more
openaire +1 more source