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Patterns of Popular Artifacts in QSM and χ-separation (chi-separation)
ISMRM Annual MeetingMotivation: In QSM and χ-separation (chi-separation), artifacts from various sources may be introduced. The oversight of these artifacts could lead researchers to analyse inaccurate maps, resulting in potentially erroneous conclusions. Goal(s): The primary objective of this research is to investigate the characteristics, origins, and solutions ...
Hayeon Lee +19 more
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In-vivo high-resolution χ-separation (chi-separation) at 7T
ISMRM Annual MeetingMotivation: High-resolution χ-separation at 7T can delineate detailed structures related to iron and myelin concentrations in the brain. However, it has the challenge of requiring an R2 map, which is not practical at 7T due to SAR and scan time. Goal(s): Our objective is to generate high-resolution χ-separation maps at 7T.
Jiye Kim +7 more
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ISMRM Annual Meeting
Motivation: QSM and health outcomes were previously evaluated for QSM in subcortical regions. Furthermore, QSM is limited by its inability to distinguish iron and myelin. Goal(s): We expanded the construction of QSM to both cortical and subcortical regions and to apply a novel method (χ-separation) the separate iron and myelin content. We evaluated the
Yun Soo Hong +10 more
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Motivation: QSM and health outcomes were previously evaluated for QSM in subcortical regions. Furthermore, QSM is limited by its inability to distinguish iron and myelin. Goal(s): We expanded the construction of QSM to both cortical and subcortical regions and to apply a novel method (χ-separation) the separate iron and myelin content. We evaluated the
Yun Soo Hong +10 more
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Physics-informed vessel segmentation for χ-separation (chi-separation)
ISMRM Annual MeetingMotivation: χ-separation is an advanced QSM method that provides para- and diamagnetic susceptibility maps. Despite its potential utilities, both maps reveal (erroneously) high intensity signals from vessels, hampering their applications and quantification.
Taechang Kim +6 more
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ISMRM Annual Meeting
The in-vivo imaging of iron and myelin concentrations of the motor cortex in amyotrophic lateral sclerosis (ALS) patients has significance in advancing knowledge about the degeneration progress of the disease. Here, we explored the feasibility of applying 𝜒-separation to ALS patients in-vivo at 7T.
Jiye Kim +11 more
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The in-vivo imaging of iron and myelin concentrations of the motor cortex in amyotrophic lateral sclerosis (ALS) patients has significance in advancing knowledge about the degeneration progress of the disease. Here, we explored the feasibility of applying 𝜒-separation to ALS patients in-vivo at 7T.
Jiye Kim +11 more
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A human brain atlas of χ-separation (chi-separation) for normative iron and myelin distributions
ISMRM Annual MeetingMotivation: Abnormal iron and myelin distributions are associated with neurodegenerative diseases. An advanced susceptibility mapping technique, χ-separation, can disentangle paramagnetic iron and diamagnetic myelin contributions in quantitative susceptibility mapping.
Kyeongseon Min +11 more
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ISMRM Annual Meeting
Motivation: Previous studies have demonstrated the correlations between iron and paramagnetic susceptibility and myelin and diamagnetic susceptibility. However, there has yet to be a quantitative layer-wise comparison with histology. Goal(s): Our objective is to validate laminar structures of χ-separation against histology in V1.
Byeongpil Moon +5 more
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Motivation: Previous studies have demonstrated the correlations between iron and paramagnetic susceptibility and myelin and diamagnetic susceptibility. However, there has yet to be a quantitative layer-wise comparison with histology. Goal(s): Our objective is to validate laminar structures of χ-separation against histology in V1.
Byeongpil Moon +5 more
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ISMRM Annual Meeting
Motivation: Important physical parameter, relaxometric constant$$$\;{D_r}$$$, linking magnetic susceptibility to induced transverse relaxation acceleration (i.e.,$$$\;{R2'}$$$) has not yet been fully understood in brain. Goal(s): To investigate underlying mechanisms affecting relaxometric constant in brain using temperature-dependent relaxometry and ...
Hyeong-Geol Shin +11 more
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Motivation: Important physical parameter, relaxometric constant$$$\;{D_r}$$$, linking magnetic susceptibility to induced transverse relaxation acceleration (i.e.,$$$\;{R2'}$$$) has not yet been fully understood in brain. Goal(s): To investigate underlying mechanisms affecting relaxometric constant in brain using temperature-dependent relaxometry and ...
Hyeong-Geol Shin +11 more
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IOP Conference Series: Earth and Environmental ScienceThe amount of household solid waste is increasing seriously in Vietnam, because of population growth, urbanization, and economic growth. Reducing the waste volume liberated to the environment needs community participation and people's awareness about the
Thao D.P. +4 more
exaly +2 more sources
ISMRM Annual Meeting
Motivation: The role of iron deposition and demyelination in amyotrophic lateral sclerosis (ALS) remains poorly understood. Investigating these factors can provide crucial insights into disease mechanisms. Goal(s): To elucidate the contributions of iron deposition versus demyelination to increased magnetic susceptibility (χ) observed in the ALS motor ...
Simi Zhou +10 more
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Motivation: The role of iron deposition and demyelination in amyotrophic lateral sclerosis (ALS) remains poorly understood. Investigating these factors can provide crucial insights into disease mechanisms. Goal(s): To elucidate the contributions of iron deposition versus demyelination to increased magnetic susceptibility (χ) observed in the ALS motor ...
Simi Zhou +10 more
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