Results 51 to 60 of about 3,625,067 (301)

Reanimating Chicago

open access: yesHumanimalia, 2016
Dave Aftandilian, and Gavin Van Horn, eds. City Creatures: Animal Encounters in the Chicago Wilderness. Chicago and London: The University of Chicago Press, 2015. xi+377 pp. $30.00 hb; $18.00 e-book.
Katharine Mershon
doaj   +1 more source

[Review of] Stow Persons. Ethnic Studies at Chicago, 1905-1945 [PDF]

open access: yes, 1988
The University of Chicago rose out of the marshes on the southside of Chicago in the 1890s to win recognition as one of the world\u27s leading research institutes.
Martinelli, Phylis Cancilla
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Reseña bibliográfica: Smith, C. (2013). City Water, City Life. Water and the Infrastructure of Ideas in Urbanizing Philadelphia, Boston, and Chicago. Chicago-London: The University of Chicago Press. 327 pp.

open access: yesAnuario de la Escuela de Historia Virtual, 2017
Reseña bibliográfica: Smith, C. (2013). City Water, City Life. Water and the Infrastructure of Ideas in Urbanizing Philadelphia, Boston, and Chicago. Chicago-London: The University of Chicago Press. 327 pp.
Cecilia Argañaraz
doaj   +1 more source

Views of Chicago: Picturing the Ruins of the Great Fire

open access: yesPanorama, 2022
By pictorially aligning the ruins of Chicago with those of the ancient civilizations of Europe, especially, these representations offered the potential for the recent past to be reframed as storied history.
Christina Michelon
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Mental Health Implications of the COVID-19 Pandemic Among Children and Adolescents: What Do We Know so Far?

open access: yesPediatric Health, Medicine and Therapeutics, 2021
Zoe I Listernick,1,2 Sherif M Badawy3,4 1Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, USA; 2Department of Medical Education, Northwestern University Feinberg School of Medicine, Chicago, IL, USA; 3Division of Hematology, Oncology ...
Listernick ZI, Badawy SM
doaj  

Chicago Foundation for Women 2012 Annual Report [PDF]

open access: yes, 2013
Chicago women and girls face difficult and inter-related issues of ecnomic security, access to education, domestic violence, immigration and access to healthcare.

core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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