Results 71 to 80 of about 2,075,947 (294)

CHICAGO NEUROLOGICAL SOCIETY [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1899
n ...
openaire   +4 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Chicago, Illinois 1984

open access: yes, 1984
Cover title: Lincoln Park map ; Depths shown by isobaths ; Includes index to points of interest ; On verso: map of Lincoln Park Zoo [ca. 1:5,000], illustrations, and text ; "This map made possible by: The R.R.
University of Illinois at Chicago. Cartographic Laboratory;
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

SART/CHICAGO Stop the Apartheid Ruby Tour press release [PDF]

open access: yes, 1981
Chicago labor, religious, black and community groups today announced the formation of a broad coalition, Stop the Apartheid Rugby Tour (SART/CHICAGO) to oppose the September 19 rugby sports match in the Chicago area sponsored by the Midwest Rugby ...
Columbia College Chicago
core   +1 more source

Using Machine Learning to Predict Likelihood and Cause of Readmission After Hospitalization for Chronic Obstructive Pulmonary Disease Exacerbation

open access: yesInternational Journal of COPD, 2022
Matthew Bonomo,1,* Michael G Hermsen,1,* Samuel Kaskovich,1 Maximilian J Hemmrich,1 Juan C Rojas,2 Kyle A Carey,3 Laura Ruth Venable,4 Matthew M Churpek,5 Valerie G Press3,6 1Pritzker School of Medicine, University of Chicago, Chicago, IL, USA ...
Bonomo M   +8 more
doaj  

Chicago Exploration Days [PDF]

open access: yesMicroscopy and Microanalysis, 2011
Extended abstract of a paper presented at Microscopy and Microanalysis 2011 in Nashville, Tennessee, USA, August 7–August 11, 2011.
openaire   +4 more sources

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

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