Results 81 to 90 of about 821,382 (263)
Neuropsychiatric Disease and Treatment, 2023 Claire A Coyne,1,2 Briahna T Yuodsnukis,1 Diane Chen1– 3 1Potocsnak Family Division of Adolescent and Young Adult Medicine, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, USA; 2Department of Psychiatry and Behavioral Sciences ...
Coyne CA, Yuodsnukis BT, Chen D
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Impact of the COVID-19 Pandemic on Cataract Surgeries in the United States
Clinical Ophthalmology, 2022 Kelly Vogel,1 Cole N Rojas,1 Paul B Greenberg,2,3 Curtis E Margo,4 Dustin D French1,5– 7 1Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; 2Division of Ophthalmology, Alpert Medical School, Brown ...
Vogel K +4 more
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Resenha de: American Catholicism
Revista de História, 1972 ELLIS (John Tracy) . — American Catholicism — The Chicago History of American Civilization. The University of Chicago Press — Chicago and London, 307 pp.
José Carlos Sebe Bom Meihy
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FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Africa Spectrum, 2010 Review of the monograph: Matthew Lange (2009), Lineages of Despotism and Development: British Colonialism and State Power, Chicago and London: The University of Chicago Press, ISBN 978-0-266-47068-9, 208 pp.
Georg Schäfer
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