Review of Exhibition catalog: Orianna Cacchione, Zhang Peili: Record. Repeat. Exh. Cat. Chicago: Art Institute of Chicago, 2017. 96 pp.; 50 color ills.
Ellen Larson
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Poverty Matters: It's Now 50/50, Chicago Region Poverty Growth is a Suburban Story [PDF]
Nationwide, the number of people in poverty in the suburbs has now surpassed the number of people in poverty in central cities. Cities have long been thought to be home to the most and worst poverty. However, in the past several decades, the suburbs have
Amy Terpstra +2 more
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Artisan Culture and the Organization of Chicago\u27s German Workers in the Gilded Age, 1860 to 1890 [PDF]
This essay evaluates the nature of German artisan culture in gilded-age Chicago and its role in the organization of modem working-class institutions. Three examples- the Workingmen\u27s Associations of Chicago\u27s German workers in the 1850s and 1860s ...
Jentz, John
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
This article focuses on second generation Latinos in the Chicago Metropolitan Area where the income gap between minority groups and Anglos is still growing. Several metropolitan Chicago Latino areas showed underemployment.
Laurence Gervais-Linon
doaj +1 more source
Creating Opportunity for Immigrant Women and Girls in the Chicago Region: Recommendations for the Chicago Foundation for Women's Civic Plan [PDF]
Division sought to understand what economic, health, and violence-related issues are most pressing for immigrant women in the Chicago region, their families, and their communities.
Amy Rynell +6 more
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

