Results 81 to 90 of about 3,625,067 (301)

Chicago Asthma Epidemic: The Status of Asthma in Chicago [PDF]

open access: yes, 2007
Chicago is known for many things, our great food and architecture. Unfortunately, we are also known for being an epi-center for asthma. We lead the Nation in asthma deaths, emergency room visits and hospitalizations.

core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Chicago Rally Speech [PDF]

open access: yes, 1984
Speech delivered to the State Federation of Labor, Chicago, IL, September 19, 1984. Includes handwritten notes and diacritic marks.https://ir.lawnet.fordham.edu/vice_presidential_campaign_speeches_1984/1113/thumbnail ...
Ferraro, Geraldine
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Variation of iStent Procedure Rates by State in Response to the COVID-19 Pandemic

open access: yesClinical Ophthalmology, 2022
Kelly Vogel,1 Cole N Rojas,1 Angelo P Tanna,1 Dustin D French1– 4 1Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA; 2Department of Medical Social Science, Northwestern University Feinberg School of ...
Vogel K, Rojas CN, Tanna AP, French DD
doaj  

The Famous Women Dinner Service: In Conversation with Contemporary Art

open access: yesBritish Art Studies, 2017
This conversation between Judy Chicago, The Women’s Art League, and Hana Leaper, filmed by Jonathan Law at the Elizabeth A. Sackler Center for Feminist Art, Brooklyn Museum, will be published in early 2018.
Judy Chicago   +4 more
doaj   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

A Staged Muon-Based Neutrino and Collider Physics Program

open access: yes, 2012
We sketch a staged plan for a series of muon-based facilities that can do compelling physics at each stage. Such a plan is unique in its ability to span both the Intensity and Energy Frontiers as defined by the P5 sub-panel of the US High Energy Physics ...
/IIT, Chicago, Kaplan, Daniel M.
core   +1 more source

Chicago Music City [PDF]

open access: yes, 2007
Chicago Music City compares the strength and vitality of music industries and scenes across the United States. Sociologists, urban planners, and real-estate developers point to quality of life and availability of cultural amenities as important ...
Daniel Silver   +4 more
core  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

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