Results 121 to 130 of about 38,045 (222)

Vacuolization as a Novel Approach to Cancer Therapy

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak, Noor Hussein, Veronica Piedra, Saloni Malla, Chandrabose Karthikeyan, Haneen Amawi, Harish Rajak, Charles R. Ashby Jr., R. Jayachandra Babu, Amit K. Tiwari   +9 more
wiley   +1 more source

Predicting Valproate-Induced Liver Injury Using Metabolomic Analysis of Ex Ovo Chick Embryo Allantoic Fluid. [PDF]

Metabolites, 2023
Tagliatti V, Descamps C, Lefèvre M, Colet JM.   +3 more
europepmc   +1 more source

Therapeutic Poxviruses Induce the Secretion of Immunostimulating and Anti‐Tumoral Extracellular Vesicles

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Immune cells infected by therapeutic poxviruses release increased amounts of extracellular vesicles bearing viral proteins and therapeutic payloads. Such EVs have the ability to activate a CD8+ T‐cell mediated antitumoral immune response and decrease tumor growth.
Lucas Walther, Vincent Mittelheisser, Marie‐Christine Claudepierre, Louis Bochler, Magali Rompais, Jules Deforges, Nathalie Silvestre, Annabel Larnicol, Christine Carapito, Eric Quémeneur, Jacky G Goetz, Karola Rittner, Vincent Hyenne   +12 more
wiley   +1 more source

Expansion microscopy of the chick embryo neural tube to overcome molecular crowding at the centrosomes-cilia. [PDF]

STAR Protoc, 2023
Wilmerding A, Espana-Bonilla P, Giakoumakis NN, Saade M.   +3 more
europepmc   +1 more source

Pathways of Protein Secretion in Prokaryotes and Eukaryotes: Molecular Mechanisms, Biological Functions, and Therapeutic Opportunities

MedComm, Volume 7, Issue 6, June 2026.
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang, Jingfei Shi, Linlin Xu, Guangrui Zhao, Yue Chen, Lin Cheng, Xiaokang Li, Zhigang Sun, Shuhong Huang   +8 more
wiley   +1 more source

4G mobile phone radiation alters some immunogenic and vascular gene expressions, and gross and microscopic and biochemical parameters in the chick embryo model. [PDF]

Vet Med Sci, 2023
Islam MS, Islam MM, Rahman MM, Islam K.
europepmc   +1 more source

Human iPSC‐NSC‐Derived Extracellular Vesicles Can Alleviate Alzheimer's Disease‐Linked Impairments in Mitochondria, mTOR Signaling, Autophagy, and Hippocampal Neurogenesis

Aging Cell, Volume 25, Issue 6, June 2026.
Intranasal administration of extracellular vesicles derived from human‐induced pluripotent stem cell‐derived neural stem cells in 5xFAD mice results in reduced oxidative stress, increased expression of proteins and genes associated with mitochondrial biogenesis and electron transport chain function, decreased mTOR activation, enhanced autophagy and ...
Leelavathi N. Madhu, Sahithi Attaluri, Sanya Kotian, Raghavendra Upadhya, Yogish Somayaji, Shama Rao, Prashant Tarale, Shruthi V. Ganesh, Charles Huard, Maheedhar Kodali, Bing Shuai, Vidya V. Rao, Ashok K. Shetty   +12 more
wiley   +1 more source

Reconstruction of distinct vertebrate gastrulation modes via modulation of key cell behaviors in the chick embryo. [PDF]

Sci Adv, 2023
Chuai M, Serrano Nájera G, Serra M, Mahadevan L, Weijer CJ.   +4 more
europepmc   +1 more source

Developmental expression of Ap‐Vas proteins in aphids and flies reveals their evolutionary roles in insects

Insect Molecular Biology, Volume 35, Issue 3, Page 217-231, June 2026.
Duplication of vas genes is universally observed in aphids, and phylogenetic analysis indicates that this event predates the divergence of Aphididae and Phylloxeridae. Ap‐vas1 is germline‐specific, whereas Ap‐vas2–4 exhibit somatic expression, indicating functional divergence during aphid embryogenesis.
Gee‐Way Lin, Szu‐Chieh Wang, Charles E. Cook, Ming‐Der Lin, Chun‐che Chang   +4 more
wiley   +1 more source

Molecular characteristics of the edge cells responsible for expansion of the chick embryo on the vitelline membrane. [PDF]

Open Biol, 2022
Lee HC, Fadaili Y, Stern CD.
europepmc   +1 more source