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The Chicken Embryo: An Old but Promising Model for In Vivo Preclinical Research [PDF]

open access: yesBiomedicines
The chicken embryo has emerged as a valuable model for preclinical studies due to its unique combination of accessibility, affordability, and relevance to human biology.
Annachiara Sarnella   +6 more
doaj   +3 more sources

The Chicken Embryo Model: A Novel and Relevant Model for Immune-Based Studies

open access: yesFrontiers in Immunology, 2021
Dysregulation of the immune system is associated with many pathologies, including cardiovascular diseases, diabetes, and cancer. To date, the most commonly used models in biomedical research are rodents, and despite the various advantages they offer ...
Paul Garcia   +7 more
doaj   +2 more sources

Transcriptional Innate Immune Response of the Developing Chicken Embryo to Newcastle Disease Virus Infection

open access: yesFrontiers in Genetics, 2018
Traditional approaches to assess the immune response of chickens to infection are through animal trials, which are expensive, require enhanced biosecurity, compromise welfare, and are frequently influenced by confounding variables.
Megan A. Schilling   +15 more
doaj   +2 more sources

Preliminary Study of Real-Time Detection of Chicken Embryo Viability Using Photoplethysmography [PDF]

open access: yesSensors
Currently, in influenza vaccine production via the chicken embryo splitting method, embryo viability detection is a pivotal quality control step—non-viable embryos are prone to microbial contamination, directly endangering the vaccine batch quality ...
Zeyu Liu   +4 more
doaj   +2 more sources

The Chicken Embryo: An Alternative Animal Model in Development, Disease and Pharmacological Treatment [PDF]

open access: yesPharmacology Research & Perspectives
To examine various medications and substances, in vivo models such as rats and mice are routinely used. However, it is utterly desirable to reduce extensive amounts of animals for these experimental models, which are costly and time‐consuming.
Oykum Kaplan‐Arabaci   +2 more
doaj   +2 more sources

THE BEHAVIOR OF CHICKEN SARCOMA IMPLANTED IN THE DEVELOPING EMBRYO

open access: yesJournal of Experimental Medicine, 1912
The direct inoculation of a sarcoma of the fowl into the developing chick embryo or its membranes has yielded growths in many cases. The best results have been obtained with grafts of the living tumor tissue, but, as in the adult, growths can be ...
Peyton Rous, Peyton Rous, J B Murphy
exaly   +2 more sources

Pathogenesis of Candida albicans infections in the alternative chorio-allantoic membrane chicken embryo model resembles systemic murine infections. [PDF]

open access: yesPLoS ONE, 2011
Alternative models of microbial infections are increasingly used to screen virulence determinants of pathogens. In this study, we investigated the pathogenesis of Candida albicans and C.
Ilse D Jacobsen   +3 more
doaj   +2 more sources

THE EFFECT OF ADULT CHICKEN ORGAN GRAFTS ON THE CHICK EMBRYO

open access: yesJournal of Experimental Medicine, 1916
The explanation of the wide-spread changes in the embryo after grafting with adult organs offers a problem of considerable interest. Just what factors are responsible for them we are unprepared to say.
J B Murphy, James B Murphy
exaly   +2 more sources

Nano-Nutrition of Chicken Embryos. The Effect of in Ovo Administration of Diamond Nanoparticles and l-Glutamine on Molecular Responses in Chicken Embryo Pectoral Muscles

open access: yesInternational Journal of Molecular Sciences, 2013
It has been demonstrated that the content of certain amino acids in eggs is not sufficient to fully support embryonic development. One possibility to supply the embryo with extra nutrients and energy is in ovo administration of nutrients.
Marta Grodzik   +2 more
exaly   +2 more sources

Smartphone-Based Device for Non-Invasive Heart-Rate Measurement of Chicken Embryos

open access: yesSensors, 2019
Heart rate (HR) is an important parameter in the study of the developmental physiology of chicken embryos and a crucial indicator of dead or live embryo grading in artificial incubation processes.
Boonsong Sutapun
exaly   +3 more sources

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