Maltase 1 regulates DENV2 infection and life history in Aedes aegypti
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li +5 more
wiley +1 more source
Chikungunya Virus as the Agent of Emergent Viral Disease
Chikungunya virus belongs to Alphavirus genus of the Togaviridae family. It is a member of Semliki Forest virus antigenic complex that includes antigenic related Semliki Forest, Chikungunya, O’ Nyong-nyong, Ross River viruses.
T. E. Sizikova +5 more
doaj +1 more source
Biological vector control with the sterile insect technique for the chilungunya disease [PDF]
Chikungunya is a vector-borne Disease, usually localized in Asia and East-Africa, with Aedes albopictus mosquito as the principal vector for the Chikungunya virus.
Dumont, Yves, Tchuenche, J.M.
core
Transmission dynamics of the ongoing chikungunya outbreak in Central Italy. From coastal areas to the metropolitan city of Rome, summer 2017 [PDF]
A large chikungunya outbreak is ongoing in Italy, with a main cluster in the Anzio coastal municipality. With preliminary epidemiological data, and a transmission model using mosquito abundance and biting rates, we estimated the basic reproduction number
Caputo, Beniamino +8 more
core +2 more sources
An All‐in‐One Metabarcoding Approach to Mosquito and Arbovirus Xenosurveillance
ABSTRACT Next‐generation sequencing (NGS) has the potential to transform mosquito‐borne disease surveillance but remains under‐utilised. This study introduces a comprehensive multi‐loci metabarcoding‐based MX (molecular xenomonitoring) approach to mosquito and arbovirus surveillance, enabling parallel identification of mosquito vectors, circulating ...
Brian J. Johnson +12 more
wiley +1 more source
Chikungunya Virus Infection [PDF]
Chikungunya virus (CHIKV) is an alphavirus transmitted by mosquitoes, mostly Aedes aegypti and Aedes albopictus. After half a century of focal outbreaks of acute febrile polyarthralgia in Africa and Asia, the disease unexpectedly spread in the past decade with large outbreaks in Africa and around the Indian Ocean and rare autochthonous transmission in ...
Fabrice Simon +4 more
openaire +3 more sources
Mutations in the E2 glycoprotein and the 3\u27 untranslated region enhance chikungunya virus virulence in mice [PDF]
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes debilitating musculoskeletal pain and inflammation and can persist for months to years after acute infection.
Carpentier, Kathryn S +8 more
core +3 more sources
ABSTRACT Viral haemorrhagic septicaemia virus (VHSV) causes a high mortality rate in cultured olive flounder, and effective treatment for VHSV infection is urgently required. Turmeric (Curcuma longa ) and liquorice (Glycyrrhiza uralensis) are well‐known medicinal plants with a variety of biological activities. Turmeric and liquorice extract combination
Su‐Mi Shin +5 more
wiley +1 more source
Chikungunya and the eye: a review [PDF]
Chikungunya is a self-limited, systemic viral infection that has been a major health problem since the past few years. Ocular manifestations of the disease have become more prevalent in the recent years. Currently, there is neither a specific treatment nor vaccine available for chikungunya fever.
Rohit Shetty +2 more
openaire +3 more sources
Unmasking the chik sign: A case report on nasal hyperpigmentation as a diagnostic clue for chikungunya fever [PDF]
Macular hyperpigmentation of the nasal region, often referred to as the ‘chik sign’, constitutes a distinctive physical manifestation associated with chikungunya fever.
Nurul Bariah Razali +2 more
doaj +1 more source

