Results 21 to 30 of about 1,757,770 (311)

A phase 1 trial of lipid-encapsulated mRNA encoding a monoclonal antibody with neutralizing activity against Chikungunya virus

open access: yesNature Medicine, 2021
Chikungunya virus (CHIKV) infection causes acute disease characterized by fever, rash and arthralgia, which progresses to severe and chronic arthritis in up to 50% of patients.
A. August   +12 more
semanticscholar   +1 more source

Chikungunya virus infection: molecular biology, clinical characteristics, and epidemiology in Asian countries

open access: yesJournal of Biomedical Sciences, 2021
Chikungunya virus (CHIKV) is a re-emerging mosquito-borne human pathogen that causes chikungunya fever, which is typically accompanied by severe joint pain. In Asia, serological evidence indicated that CHIKV first emerged in 1954. From the 1950’s to 2005,
Sarawut Khongwichit   +3 more
semanticscholar   +1 more source

Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1.

open access: yesCell Host and Microbe, 2021
Chikungunya virus (CHIKV) causes a debilitating arthralgic inflammatory disease in humans. The multifunctional CHIKV protein, nsP1, facilitates virus RNA replication and transcription by anchoring the viral replication complex (RC) to plasma membrane ...
Kuo Zhang   +5 more
semanticscholar   +1 more source

Antivirals against the Chikungunya Virus

open access: yesViruses, 2021
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that has re-emerged in recent decades, causing large-scale epidemics in many parts of the world.
Verena Battisti, E. Urban, T. Langer
semanticscholar   +1 more source

New Insights into Chikungunya Virus Infection and Pathogenesis.

open access: yesAnnual Review of Virology, 2021
Chikungunya virus (CHIKV) is a re-emerging mosquito-borne alphavirus responsible for major outbreaks of disease since 2004 in the Indian Ocean islands, South east Asia, and the Americas.
Vasiliya Kril   +3 more
semanticscholar   +1 more source

Large-scale outbreak of Chikungunya virus infection in Thailand, 2018–2019

open access: yesPLoS ONE, 2021
Between 2018 and 2019, the incidence of chikungunya was approximately 15,000 cases across 60 provinces in Thailand. Here, the clinical presentations in chikungunya, emergent pattern, and genomic diversity of the chikungunya virus (CHIKV) causing this ...
Sarawut Khongwichit   +6 more
semanticscholar   +1 more source

The Phosphatidylserine Receptor TIM-1 Enhances Authentic Chikungunya Virus Cell Entry

open access: yesCells, 2021
Chikungunya virus (CHIKV) is a re-emerging, mosquito-transmitted, enveloped positive stranded RNA virus. Chikungunya fever is characterized by acute and chronic debilitating arthritis.
Jared Kirui   +8 more
semanticscholar   +1 more source

Chikungunya Virus

open access: yesClinics in Laboratory Medicine, 2017
For chikungunya virus (CHIKV), the long-term sequelae from infection are yet ill-defined. The prolonged debilitating arthralgia associated with CHIKV infection has tremendous potential for impacting the global economy and should be considered when evaluating the human burden of disease and the allocation of resources.
Vu, David M.   +2 more
openaire   +2 more sources

Chikungunya virus infection in developing countries - What should we do?

open access: yesJournal of Advanced Veterinary and Animal Research, 2017
Chikungunya fever, a serious global public health problem, is a mosquito-borne disease caused by Chikungunya virus belonging to the family Togaviridae. The virus was first detected in Tanzania in1953.
Md. Tanvir Rahman
doaj   +1 more source

Susceptibility of various cell lines to the Chikungunya virus and method selection for commercial-scale production of viral material

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2023
An increase in cases of chikungunya fever is reported in the Caribbean, Central and South America, and Southeast Asia. As there is no specific treatment for this disease and the only available treatment is symptomatic, it is very relevant to develop ...
K. V. Kaa   +3 more
doaj   +1 more source

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